Ordering the Th1 Th2 Th17 Cytokine Test | Advanced | Canada
The Th1 Th2 Th17 Cytokine Test helps identify immune system imbalances by measuring specific cytokines, which are proteins that guide immune responses. This test is often used to help people with autoimmune conditions, allergies, or chronic inflammation find out if their immune system is leaning more toward Th1, Th2, or Th17 dominance. Interestingly, some botanicals and supplements can shift these immune responses, so knowing your cytokine levels can help your doctor make more targeted recommendations.
Ordering this test can provide:
- Clear measurement of Th1, Th2, and Th17 cytokines to pinpoint immune system patterns
- Support for doctors to create more focused treatment plans for autoimmune or inflammatory issues
- Insight into possible triggers for symptoms like joint pain, skin rashes, or digestive problems
- Guidance for adjusting supplements or therapies that may affect immune balance
- Tracking of immune changes over time to see if treatments are working
Who Should Consider Immune Cytokine Balance Testing
People who have ongoing symptoms like joint pain, skin rashes, or digestive discomfort that do not improve with standard care may benefit from this test. For example, someone who has tried several diets and medications for eczema but still has flare-ups could use this test to see if an immune imbalance is playing a role.
Ordering this test may also be helpful in these situations:
- People with a family history of autoimmune conditions who want to check for early immune changes
- Those with frequent infections or slow recovery from common illnesses
- Anyone experiencing unexplained fatigue, brain fog, or mood swings
- People with chronic inflammatory conditions like Crohn’s disease or psoriasis
- Someone who has noticed that their symptoms get worse after certain foods or environmental exposures, which may be linked to immune system shifts
Testing for cytokine patterns can help identify if immune system activity is contributing to symptoms like inflammation, skin problems, or digestive issues. Delaying this test could mean missing the chance to adjust treatments early, which may allow symptoms to continue or worsen.
Preparing for Cytokine and Immune Marker Testing
Fasting is not required for this test, so you can eat and drink as usual before your blood draw. Always follow any instructions your doctor or healthcare provider gives you to make sure your sample is collected and shipped correctly.
Labs Included When Ordering Your Th1 Th2 Th17 Cytokine Test | Advanced
| Test Name | Reference Range | What This Marker Means | Low and High Levels of Th1 Th2 Th17 Cytokine Test |
|---|---|---|---|
| Th1 Cytokines | |||
| INF Gamma | 5-50 | INF Gamma is a Th1 cytokine that helps activate immune cells to fight infections and control inflammation. It is important for defending against viruses and some bacteria. |
High levels mean the immune system may be overactive, possibly linked to autoimmune activity or chronic inflammation.
Low levels mean the body may have trouble fighting infections or may be more prone to certain illnesses. |
| IL-1 beta | 0.5-5 | IL-1 beta is a Th1 cytokine that triggers inflammation and helps the body respond to injury or infection. It is often linked to joint pain and swelling. |
High levels mean there may be ongoing inflammation, which can worsen joint or tissue problems.
Low levels mean the body may not respond strongly to infections or injuries. |
| IL-2 | 2-10 | IL-2 is a Th1 cytokine that helps immune cells grow and multiply. It is important for keeping the immune system balanced and active. |
High levels mean the immune system may be overactive, which can lead to tissue damage.
Low levels mean immune cells may not multiply well, making it harder to fight infections. |
| IL-6 | 0.5-5 | IL-6 is produced by both Th1 and Th2 cells and is involved in inflammation and infection responses. It can also affect mood and energy levels. |
High levels mean there may be chronic inflammation or infection.
Low levels mean the immune response may be weak or slow. |
| IL-7 | 1-10 | IL-7 is a weak Th1 cytokine that helps immune cells survive and develop. It is important for keeping the immune system ready to respond. |
High levels mean the immune system may be trying to recover from stress or infection.
Low levels mean immune cell numbers may be low, making it harder to respond to new threats. |
| IL-8 | 5-50 | IL-8 is a weak Th1 cytokine that attracts immune cells to sites of infection or injury. It is often linked to inflammation in the gut and skin. |
High levels mean there may be active inflammation or infection.
Low levels mean fewer immune cells are being sent to areas that need repair. |
| IL-12 p70 | 1-7 | IL-12 p70 is a Th1 cytokine that helps direct the immune system to fight viruses and bacteria. It also helps balance Th1 and Th2 responses. |
High levels mean the immune system may be overreacting to infections.
Low levels mean the body may not fight infections as well. |
| IL-17A | 0.5-5 | IL-17A is a Th17 cytokine that helps protect against bacteria and fungi. It is often linked to autoimmune and inflammatory conditions. |
High levels mean there may be increased risk for autoimmune or chronic inflammatory problems.
Low levels mean the body may be less able to fight certain infections. |
| IL-18 | 1-10 | IL-18 is a weak Th1 cytokine that helps boost immune responses and inflammation. It works with other cytokines to fight infections. |
High levels mean there may be ongoing inflammation or immune activation.
Low levels mean the immune system may not respond strongly to threats. |
| TNF alpha | 1-8 | TNF alpha is a Th1 cytokine that helps control inflammation and immune cell activity. It is often linked to joint pain and autoimmune symptoms. |
High levels mean there may be active inflammation or tissue damage.
Low levels mean the immune response may be weak or slow. |
| Th2 Cytokines | |||
| IL-4 | 0.5-5 | IL-4 is a Th2 cytokine that helps the body make antibodies and control allergic responses. It is important for fighting parasites and calming inflammation. |
High levels mean there may be more allergies or asthma symptoms.
Low levels mean the body may not make enough antibodies to fight some infections. |
| IL-5 | 0.5-5 | IL-5 is a Th2 cytokine that helps control certain white blood cells called eosinophils. It is often linked to allergies and asthma. |
High levels mean there may be more allergic or asthma symptoms.
Low levels mean the body may not respond well to parasites or allergens. |
| IL-10 | 1-10 | IL-10 is made by T-regulatory cells and helps calm inflammation. It keeps the immune system from attacking the body’s own tissues. |
High levels mean the immune system may be too calm, which can allow infections to linger.
Low levels mean there may be more risk for autoimmune or inflammatory problems. |
| IL-13 | 0.5-5 | IL-13 is a Th2 cytokine that helps control allergic reactions and supports tissue repair. It is often linked to asthma and skin problems. |
High levels mean there may be more allergies, asthma, or skin rashes.
Low levels mean the body may not repair tissues as well after injury. |
| IL-15 | 1-10 | IL-15 is a weak Th2 cytokine that helps immune cells grow and survive. It is important for keeping the immune system balanced. |
High levels mean the immune system may be overactive.
Low levels mean immune cell numbers may be low, making it harder to respond to threats. |
Reference ranges may change slightly as labs update their standards, so always check your report for the most current values.
Th1 Th2 Th17 Cytokine Test FAQ
Is there Th1 Th2 Th17 Cytokine testing near me?
This is a test kit that can be collected at a local draw site—see the draw location link at the top of the page. For people with ongoing inflammation or autoimmune symptoms, having a nearby collection site makes it easier to get tested quickly and start finding answers.
How do I interpret the test results?
While your treating physician should review your results, we also offer a one-on-one test results review with our clinical team to help you understand your cytokine patterns and what they may mean for your symptoms.
What is the cost of the test?
The price listed for this test includes standard shipping to you and return shipping to the lab, but local draw fees may apply. Ordering this test can help you and your doctor find out if immune imbalances are slowing your progress, so you can adjust your plan sooner.
How often should I retest?
Retesting is usually recommended every 3-6 months, especially if you are starting a new treatment or making changes to your care plan. This helps track how your immune system is responding and if your cytokine levels are moving in the right direction.
How accurate is the test?
This test uses multiplex immunoassay technology, which measures multiple cytokines in a single blood sample for precise results. The specificity is 98% and sensitivity is 97%. TrueHealthLabs.com partners with CLIA-certified and CAP-certified laboratories to uphold rigorous testing standards for dependable results.
Important Notes
- This test is only available in the USA except for the state of New York. Contact us for questions.
- Specimen must be returned overnight. Ship samples on Mondays or Tuesdays.
Medical Review Board
Reviewed by Jeff Donohue M.D. from Body Logic and Brady Hurst DC, CCCN. Written by True Health Lab’s team of editorial health contributors.
Disclaimer: This information is for educational purposes only and not intended as medical advice. Consult your healthcare provider for personalized guidance.
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