Ordering the Streptococcus Antibodies Profile by Great Plains
The Streptococcus Antibodies Profile by Great Plains helps detect antibodies that form after a group A strep infection, which can lead to joint pain, skin rashes, or even kidney problems. This test is often used to check for past infections that may be linked to conditions like rheumatic fever or post-streptococcal glomerulonephritis. Interestingly, high levels of these antibodies have also been found in people with certain neurological symptoms, such as tics or obsessive-compulsive behaviors.
Ordering this test can help you and your doctor pinpoint if a recent or past strep infection is connected to ongoing symptoms. When you order the Streptococcus Antibodies Profile, you get:
- Detection of both DNase B and antistreptolysin O (ASO) antibodies for a more complete picture
- Helps identify if strep bacteria may be causing joint, skin, or neurological symptoms
- Supports diagnosis of post-streptococcal complications, including rheumatic fever and glomerulonephritis
- Assists in monitoring antibody levels over time to track recovery or recurrence
- Provides information that can guide further treatment or specialist referral
Who Should Consider Streptococcal Antibody Testing
People who have had a sore throat, fever, or skin rash that did not go away quickly, and now experience joint pain or unusual tiredness, may benefit from this test. For example, a child who had strep throat a few weeks ago and now has new tics or behavior changes could have lingering antibodies that this test can detect.
Ordering this test may also be helpful in these situations:
- Someone with repeated ear or sinus infections that do not respond to usual treatments
- Anyone with unexplained joint swelling or pain after a recent illness
- Children with sudden changes in mood, behavior, or movement patterns
- People with a history of scarlet fever or rheumatic fever who develop new symptoms
- Those with a family member diagnosed with PANDAS or similar autoimmune conditions, as antibody levels can sometimes run high in related cases
This test should be ordered to help confirm if a previous strep infection is linked to ongoing symptoms, such as joint pain, skin changes, or neurological issues. Delaying this test could mean missing the best window to connect symptoms to a past infection, which may affect treatment decisions.
Preparing for Streptococcal Antibody Screening
Fasting is not required for this test, but always check the test kit instructions for any special requirements. Make sure to follow whatever guidance your doctor or healthcare practitioner gives you, as this can help ensure your sample is collected correctly and your results are as useful as possible.
Labs Included When Ordering Your Streptococcus Antibodies Profile by Great Plains
| Test Name | Reference Range | What the Biomarker Means | Low and High Levels of Streptococcus Antibodies Profile |
|---|---|---|---|
| DNase B Antibodies | 0–85 | DNase B antibodies are made by the body after a group A strep infection. High levels can show a recent or ongoing strep infection, even if symptoms are mild or gone. |
High levels mean your body is reacting to a recent or ongoing strep infection, which may be linked to joint, kidney, or neurological symptoms.
Low levels mean there is little or no immune response to strep bacteria, suggesting no recent infection. |
| Antistreptolysin O (ASO) Titer | 0–200 | ASO titer measures antibodies against a toxin made by strep bacteria. High ASO levels can show a recent strep infection, even if you did not have classic symptoms. |
High levels mean your immune system has recently fought a strep infection, which can be linked to joint pain, skin rash, or kidney issues.
Low levels mean there is no sign of a recent strep infection or your body did not make many antibodies. |
Reference ranges may change slightly as labs update their methods or as new research becomes available.
Streptococcus Antibodies Profile FAQ
Is there Streptococcus Antibodies Profile testing near me?
This is a test kit that can be collected at a local draw site—check the draw location link at the top of the page. For people dealing with ongoing joint pain or neurological symptoms after a strep infection, having a nearby collection site makes it easier to get tested quickly and start finding answers.
How do I interpret the test results?
While your treating physician should always help you interpret your results, we also offer a one-on-one test results review with our clinical team to help you understand what your numbers mean and what steps to take next.
What is the cost of the test?
The price you see for the test includes standard shipping to you and back to the lab, but draw fees may apply at your local collection site. Ordering this test can help you find out if a past strep infection is causing your current symptoms, which can help you get the right treatment sooner.
How often should I retest?
Retesting is usually recommended every 4–6 weeks if symptoms continue or if your doctor is monitoring your recovery from a strep-related illness. Tracking changes in antibody levels over time can help show if your immune response is going down or if a new infection has happened.
How accurate is the test?
This test uses enzyme immunoassay (EIA) and latex agglutination methods, which are highly specific for detecting DNase B and ASO antibodies. The specificity is about 95% and the sensitivity is around 90%. TrueHealthLabs.com partners with CLIA-certified and CAP-certified laboratories to uphold rigorous testing standards for dependable results.
Important Notes
- This test can not be collected or mailed from New York State. Contact us with questions.
Medical Review Board
Reviewed by Jeff Donohue M.D. from Body Logic and Brady Hurst DC, CCCN. Written by True Health Lab’s team of editorial health contributors.
Disclaimer: This information is for educational purposes only and not intended as medical advice. Consult your healthcare provider for personalized guidance.
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