Ordering the Organic Acids Test | Vibrant Wellness
The Organic Acids Test by Vibrant Wellness helps identify imbalances in metabolism, gut bacteria, yeast, and nutrient absorption. This test can reveal patterns linked to fatigue, mood changes, digestive discomfort, and skin issues. Interestingly, certain organic acids in urine can show early signs of vitamin deficiencies before symptoms appear, making this test a practical tool for those seeking answers to unexplained symptoms.
Ordering this test provides:
- Detailed analysis of over 40 organic acid markers for gut bacteria, yeast, and mitochondrial function
- Detection of nutrient deficiencies, including B vitamins and antioxidants
- Assessment of detoxification pathways and oxidative stress
- Insight into energy production and metabolism
- Identification of imbalances that may contribute to mood, focus, and sleep issues
Who Should Consider Metabolic and Gut Health Testing
People who experience ongoing tiredness, brain fog, or digestive discomfort may benefit from this test. For example, someone who feels drained after eating, struggles with focus at work, and notices frequent bloating could use this test to pinpoint possible metabolic or gut-related causes.
Ordering may also be helpful in these situations:
- Frequent mood swings or unexplained irritability
- Difficulty maintaining a healthy weight despite diet changes
- Recurring skin rashes or acne that do not respond to typical treatments
- Persistent joint stiffness or muscle aches without clear injury
- Unusual sensitivity to certain foods, such as headaches after eating grapes or apples
This test can help identify specific metabolic or gut imbalances that may be affecting energy, digestion, and nutrient absorption. Delaying this test could mean missing early signs of nutrient deficiencies or gut imbalances, which may become harder to address over time.
Preparing for Urine Organic Acids Analysis
Fasting is not required for this test, but you should avoid apples, grapes, raisins, pears, cranberries, and related juices for 48 hours before collecting your sample. Make sure to carefully follow any instructions your doctor or healthcare provider gives you to ensure your sample is collected correctly and your results are as useful as possible.
Labs Included When Ordering Your Organic Acids Test | Vibrant Wellness
| Test Name | Reference Range | What This Marker Means | Low and High Levels of Organic Acids Test | Vibrant Wellness |
|---|---|---|---|
| INTESTINAL MICROBIAL OVERGROWTH | |||
| Citramalic Acid | 0–7 | Citramalic acid is a marker for yeast and some bacterial overgrowth in the gut. High levels may indicate fungal or yeast imbalance. |
High levels mean possible yeast or fungal overgrowth in the digestive tract.
Low levels mean normal yeast and bacterial activity. |
| 5-Hydroxymethyl-furoic Acid | 0–2 | This marker is linked to yeast metabolism. It can help detect hidden fungal imbalances in the gut. |
High levels mean increased yeast or fungal activity.
Low levels mean yeast overgrowth is unlikely. |
| 3-Oxoglutaric Acid | 0–3 | 3-Oxoglutaric acid is produced by yeast and some bacteria. It can signal gut microbial imbalance. |
High levels mean possible yeast or bacterial overgrowth.
Low levels mean balanced gut flora. |
| Furan-2,5-dicarboxylic Acid | 0–2 | This acid is a byproduct of yeast metabolism and can indicate fungal activity in the gut. |
High levels mean increased yeast or fungal presence.
Low levels mean normal yeast activity. |
| Furancarbonylglycine | 0–2 | Furancarbonylglycine is another marker for yeast overgrowth, especially in the digestive tract. |
High levels mean possible yeast imbalance.
Low levels mean yeast is not elevated. |
| Tartaric Acid | 0–3 | Tartaric acid is produced by yeast, especially Candida species, and can signal overgrowth. |
High levels mean possible Candida or yeast overgrowth.
Low levels mean yeast is not overproducing. |
| Arabinose | 0–47 | Arabinose is a sugar alcohol produced by yeast. It is a sensitive marker for fungal overgrowth. |
High levels mean likely yeast or fungal overgrowth.
Low levels mean yeast is not elevated. |
| Carboxycitric Acid | 0–2 | This acid is linked to yeast and mold exposure. It can help detect hidden fungal issues. |
High levels mean possible mold or yeast exposure.
Low levels mean no significant exposure. |
| Tricarballylic Acid | 0–2 | Tricarballylic acid is a marker for mold exposure and can indicate environmental or food-related sources. |
High levels mean possible mold exposure.
Low levels mean no significant mold exposure. |
| Hippuric Acid | 0–250 | Hippuric acid is a bacterial marker and can reflect gut bacteria activity or exposure to certain foods and chemicals. |
High levels mean increased bacterial activity or chemical exposure.
Low levels mean normal bacterial metabolism. |
| 2-Hydroxyphenylacetic Acid | 0–5 | This marker is produced by gut bacteria and can indicate imbalances in the digestive tract. |
High levels mean possible bacterial overgrowth.
Low levels mean balanced gut bacteria. |
| 4-Hydroxybenzoic Acid | 0–5 | 4-Hydroxybenzoic acid is a byproduct of bacterial metabolism and can signal changes in gut flora. |
High levels mean increased bacterial activity.
Low levels mean normal bacterial metabolism. |
| 4-Hydroxyhippuric Acid | 0–5 | This acid is linked to gut bacteria and can reflect changes in the digestive environment. |
High levels mean possible bacterial imbalance.
Low levels mean balanced gut flora. |
| DHPPA | 0–2 | Dihydroxyphenylpropionic acid is a marker for beneficial bacteria in the gut. |
High levels mean increased beneficial bacteria.
Low levels mean possible lack of healthy gut bacteria. |
| 4-Hydroxyphenylacetic Acid | 0–5 | This marker is produced by Clostridia bacteria and can indicate overgrowth in the gut. |
High levels mean possible Clostridia overgrowth.
Low levels mean normal Clostridia levels. |
| HPHPA | 0–3 | HPHPA is a specific marker for Clostridia bacteria, which can affect mood and behavior. |
High levels mean possible Clostridia overgrowth.
Low levels mean Clostridia is not elevated. |
| 4-Cresol | 0–2 | 4-Cresol is a byproduct of certain gut bacteria and can signal imbalance or overgrowth. |
High levels mean possible bacterial imbalance.
Low levels mean normal bacterial activity. |
| 3-Indoleacetic Acid | 0–10 | This acid is produced by gut bacteria and can reflect protein breakdown in the digestive tract. |
High levels mean increased protein breakdown or bacterial activity.
Low levels mean normal protein metabolism. |
| INDICATORS OF DETOXIFICATION | |||
| Pyroglutamic Acid | 0–40 | Pyroglutamic acid is a marker for glutathione status, which is important for detoxification and antioxidant defense. |
High levels mean possible glutathione depletion or oxidative stress.
Low levels mean normal glutathione metabolism. |
| 2-Hydroxybutyric Acid | 0–7 | This acid is linked to glutathione production and can signal oxidative stress or detoxification issues. |
High levels mean increased oxidative stress or detoxification demand.
Low levels mean normal detoxification. |
| Orotic Acid | 0–2 | Orotic acid is a marker for ammonia excess and can indicate problems with protein metabolism or detoxification. |
High levels mean possible ammonia buildup or detoxification issues.
Low levels mean normal ammonia metabolism. |
| 2-Hydroxyhippuric Acid | 0–2 | This acid can reflect exposure to aspartame, salicylates, or certain gut bacteria. |
High levels mean possible exposure to aspartame, salicylates, or gut bacteria imbalance.
Low levels mean no significant exposure. |
| MITOCHONDRIAL MARKERS | |||
| Succinic Acid | 0–17 | Succinic acid is a key part of the Krebs cycle, which produces energy in cells. It can show how well mitochondria are working. |
High levels mean possible mitochondrial dysfunction or energy production issues.
Low levels mean normal mitochondrial function. |
| Fumaric Acid | 0–5 | Fumaric acid is another Krebs cycle marker and can reflect energy metabolism in the body. |
High levels mean possible mitochondrial or metabolic stress.
Low levels mean normal energy metabolism. |
| Malic Acid | 0–7 | Malic acid is involved in energy production and can indicate how well cells are making energy. |
High levels mean possible mitochondrial dysfunction.
Low levels mean normal energy production. |
| 2-Oxoglutaric Acid | 0–7 | This acid is part of the Krebs cycle and can show how well mitochondria are working. |
High levels mean possible mitochondrial or metabolic issues.
Low levels mean normal mitochondrial function. |
| Aconitic Acid | 0–7 | Aconitic acid is a Krebs cycle intermediate and can reflect energy metabolism in cells. |
High levels mean possible mitochondrial stress.
Low levels mean normal energy metabolism. |
| Citric Acid | 0–300 | Citric acid is a main part of the Krebs cycle and helps measure how well the body produces energy. |
High levels mean possible mitochondrial or metabolic imbalance.
Low levels mean normal energy production. |
| 3-Methylglutaric Acid | 0–2 | This acid is an amino acid metabolite and can indicate mitochondrial function or certain metabolic disorders. |
High levels mean possible mitochondrial dysfunction.
Low levels mean normal mitochondrial activity. |
| 3-Methylglutaconic Acid | 0–2 | 3-Methylglutaconic acid is linked to mitochondrial function and can signal metabolic stress. |
High levels mean possible mitochondrial or metabolic disorder.
Low levels mean normal metabolism. |
| 3-Hydroxyglutaric Acid | 0–2 | This acid is a marker for mitochondrial and amino acid metabolism. |
High levels mean possible mitochondrial dysfunction.
Low levels mean normal mitochondrial activity. |
| AMINO ACID METABOLITES | |||
| 2-Hydroxyisovaleric Acid | 0–2 | This acid is a byproduct of amino acid breakdown and can indicate issues with protein metabolism. |
High levels mean possible amino acid metabolism disorder.
Low levels mean normal protein breakdown. |
| 3-Methyl-2-oxovaleric Acid | 0–2 | This marker is linked to branched-chain amino acid metabolism and can signal metabolic stress. |
High levels mean possible amino acid metabolism issue.
Low levels mean normal metabolism. |
| 2-Hydroxyisocaproic Acid | 0–2 | This acid is a byproduct of leucine metabolism and can indicate protein breakdown issues. |
High levels mean possible protein metabolism disorder.
Low levels mean normal protein metabolism. |
| 2-Oxoisocaproic Acid | 0–2 | This marker is linked to amino acid metabolism and can signal metabolic stress or imbalance. |
High levels mean possible amino acid metabolism issue.
Low levels mean normal metabolism. |
| 2-Oxo-4-methiolbutyric Acid | 0–2 | This acid is a byproduct of methionine metabolism and can indicate protein breakdown issues. |
High levels mean possible methionine metabolism disorder.
Low levels mean normal methionine metabolism. |
| Mandelic Acid | 0–2 | Mandelic acid is a byproduct of amino acid metabolism and can reflect detoxification or metabolic stress. |
High levels mean possible detoxification or metabolic issue.
Low levels mean normal metabolism. |
| Phenyllactic Acid | 0–2 | This acid is a byproduct of phenylalanine metabolism and can indicate metabolic or detoxification issues. |
High levels mean possible phenylalanine metabolism disorder.
Low levels mean normal metabolism. |
| Phenylpyruvic Acid | 0–2 | Phenylpyruvic acid is a marker for phenylalanine metabolism and can signal metabolic stress. |
High levels mean possible phenylalanine metabolism disorder.
Low levels mean normal metabolism. |
| Homogentisic Acid | 0–2 | This acid is a byproduct of tyrosine metabolism and can indicate metabolic or detoxification issues. |
High levels mean possible tyrosine metabolism disorder.
Low levels mean normal metabolism. |
| 4-Hydroxyphenyllactic Acid | 0–2 | This acid is a byproduct of tyrosine metabolism and can signal metabolic or detoxification issues. |
High levels mean possible tyrosine metabolism disorder.
Low levels mean normal metabolism. |
| N-Acetylaspartic Acid | 0–2 | N-Acetylaspartic acid is a marker for amino acid metabolism and can reflect brain or metabolic health. |
High levels mean possible metabolic or neurological issue.
Low levels mean normal metabolism. |
| Malonic Acid | 0–2 | Malonic acid is a byproduct of amino acid metabolism and can indicate metabolic stress. |
High levels mean possible metabolic disorder.
Low levels mean normal metabolism. |
| TRYPTOPHAN METABOLITES | |||
| Glyceric Acid | 0–2 | Glyceric acid is a byproduct of tryptophan metabolism and can indicate metabolic or detoxification issues. |
High levels mean possible tryptophan metabolism disorder.
Low levels mean normal metabolism. |
| Glycolic Acid | 0–2 | Glycolic acid is a byproduct of tryptophan metabolism and can signal metabolic or detoxification issues. |
High levels mean possible tryptophan metabolism disorder.
Low levels mean normal metabolism. |
| Oxalic Acid | 0–40 | Oxalic acid is a byproduct of tryptophan metabolism and can indicate metabolic or detoxification issues. |
High levels mean possible tryptophan metabolism disorder.
Low levels mean normal metabolism. |
| KETONE AND FATTY ACID OXIDATION | |||
| 3-Hydroxybutyric Acid | 0–2 | This acid is a marker for fat breakdown and can indicate how well the body uses fat for energy. |
High levels mean increased fat breakdown or possible metabolic stress.
Low levels mean normal fat metabolism. |
| Acetoacetic Acid | 0–2 | Acetoacetic acid is a ketone body and can reflect fat metabolism or fasting state. |
High levels mean increased fat breakdown or fasting.
Low levels mean normal fat metabolism. |
| 4-Hydroxybutyric Acid | 0–2 | This acid is a byproduct of fat metabolism and can indicate how well the body uses fat for energy. |
High levels mean increased fat breakdown.
Low levels mean normal fat metabolism. |
| Adipic Acid | 0–2 | Adipic acid is a marker for fat metabolism and can signal metabolic stress or fasting. |
High levels mean increased fat breakdown or metabolic stress.
Low levels mean normal fat metabolism. |
| Suberic Acid | 0–2 | Suberic acid is a byproduct of fat metabolism and can indicate how well the body uses fat for energy. |
High levels mean increased fat breakdown.
Low levels mean normal fat metabolism. |
| Sebacic Acid | 0–2 | Sebacic acid is a marker for fat metabolism and can signal metabolic stress or fasting. |
High levels mean increased fat breakdown or metabolic stress.
Low levels mean normal fat metabolism. |
| Ethylmalonic Acid | 0–2 | Ethylmalonic acid is a byproduct of fat metabolism and can indicate metabolic or mitochondrial issues. |
High levels mean possible mitochondrial or metabolic disorder.
Low levels mean normal metabolism. |
| Methylsuccinic Acid | 0–2 | Methylsuccinic acid is a byproduct of fat metabolism and can signal metabolic or mitochondrial issues. |
High levels mean possible mitochondrial or metabolic disorder.
Low levels mean normal metabolism. |
| GLYCOLYTIC CYCLE METABOLITES | |||
| Lactic Acid | 0–20 | Lactic acid is a byproduct of glucose metabolism and can indicate how well the body uses sugar for energy. |
High levels mean increased glycolysis or metabolic stress.
Low levels mean normal glucose metabolism. |
| Pyruvic Acid | 0–2 | Pyruvic acid is a key part of glucose metabolism and can reflect energy production in cells. |
High levels mean increased glycolysis or metabolic stress.
Low levels mean normal glucose metabolism. |
| PYRIMIDINE METABOLITES | |||
| Uracil | 0–2 | Uracil is a marker for DNA and RNA metabolism and can indicate metabolic or detoxification issues. |
High levels mean possible DNA or RNA metabolism disorder.
Low levels mean normal metabolism. |
| Thymine | 0–2 | Thymine is a marker for DNA metabolism and can signal metabolic or detoxification issues. |
High levels mean possible DNA metabolism disorder.
Low levels mean normal metabolism. |
| NUTRITIONAL MARKERS | |||
| N-Acetylcysteine Acid | 0–2 | This acid is a marker for antioxidant status and can reflect glutathione metabolism. |
High levels mean possible antioxidant or glutathione metabolism issue.
Low levels mean normal antioxidant status. |
| Methylcitric Acid | 0–2 | Methylcitric acid is a marker for vitamin B12 status and can indicate metabolic or nutritional issues. |
High levels mean possible vitamin B12 deficiency.
Low levels mean normal vitamin B12 status. |
| Methylmalonic Acid (Vit B12) | 0–2 | Methylmalonic acid is a sensitive marker for vitamin B12 deficiency and can help detect early changes. |
High levels mean possible vitamin B12 deficiency.
Low levels mean normal vitamin B12 status. |
| Pyridoxic Acid (Vit B6) | 0–2 | Pyridoxic acid is a marker for vitamin B6 status and can indicate nutritional or metabolic issues. |
High levels mean possible vitamin B6 deficiency.
Low levels mean normal vitamin B6 status. |
| Pantothenic Acid (Vit B5) | 0–2 | Pantothenic acid is a marker for vitamin B5 status and can reflect nutritional or metabolic issues. |
High levels mean possible vitamin B5 deficiency.
Low levels mean normal vitamin B5 status. |
| Glutaric Acid (Vit B2) | 0–2 | Glutaric acid is a marker for vitamin B2 status and can indicate nutritional or metabolic issues. |
High levels mean possible vitamin B2 deficiency.
Low levels mean normal vitamin B2 status. |
| Ascorbic Acid (Vit C) | 0–2 | Ascorbic acid is a marker for vitamin C status and can reflect nutritional or metabolic issues. |
High levels mean possible vitamin C deficiency.
Low levels mean normal vitamin C status. |
Reference ranges may change slightly as labs update their methods and improve testing over time.
Organic Acids Test | Vibrant Wellness FAQ
Is there Organic Acids Test | Vibrant Wellness testing near me?
This is a home test kit, so you can collect your urine sample locally and send it to the lab using the prepaid shipping label. If you have trouble with energy, mood, or digestion, being able to collect your sample at home makes it easier to get answers without traveling to a clinic.
How do I interpret the test results?
While your treating physician should review your results, we also offer a one-on-one test results review with our clinical team to help you understand your results and next steps.
What is the cost of the test?
The price you see includes standard shipping to your address and return shipping to the lab; draw fees may apply if you need a blood draw for other tests. Ordering this test can help you find out if nutrient imbalances or gut issues are slowing your progress, so you can address them sooner.
How often should I retest?
Retesting is usually recommended every 3–6 months, especially if you are making changes to your diet or supplements, or if your symptoms change. Regular retesting helps track improvements and catch new imbalances early.
How accurate is the test?
This test uses advanced mass spectrometry and gas chromatography to measure organic acids in urine, with a specificity of 98% and sensitivity of 97%. TrueHealthLabs.com partners with CLIA-certified and CAP-certified laboratories to uphold rigorous testing standards for dependable results.
Important Notes
- This test is available in the USA (excluding NY State).
- We do not advise discontinuing any necessary medications or supplements. We recommend you consult with your primary doctor before making any changes to your medication or supplement intake.
- Some foods can affect the test results. We recommend avoiding apples, grapes, raisins, pears, cranberries, dried cranberries, and any juices from these fruits for 48 hours before collecting your samples. You should also avoid the following supplements which may affect test results if taken within 48 hrs prior to the collection: ribose, arabinogalactan, echinacea, and reishi mushrooms.
Medical Review Board
Reviewed by Jeff Donohue M.D. from Body Logic and Brady Hurst DC, CCCN. Written by True Health Lab’s team of editorial health contributors.
Disclaimer: This information is for educational purposes only and not intended as medical advice. Consult your healthcare provider for personalized guidance.
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