Ordering the Male Serum Profile | ZRT Labs
Ordering the Male Serum Profile from ZRT Labs helps check key hormone and thyroid markers that can affect energy, mood, muscle mass, and more. Interestingly, this test can also help spot early changes in hormone levels that may not yet cause obvious symptoms, giving a chance to address issues before they progress.
When ordering this test, you can expect these specific benefits:
- Measures testosterone, estrogen, and DHEA to help identify hormone imbalances that may affect muscle strength, mood, and sexual function.
- Checks thyroid markers, including TSH, Free T3, and Free T4, to help explain changes in weight, energy, or temperature sensitivity.
- Assesses prostate-specific antigen (PSA) to monitor prostate health.
- Evaluates cortisol at two points in the day to help understand stress response and fatigue patterns.
- Includes Hashimoto’s screening to detect early thyroid autoimmunity, which can impact metabolism and energy.
Who Should Consider Comprehensive Male Hormone and Thyroid Testing
Someone who has been feeling more tired than usual, noticing changes in mood, or struggling with low motivation might benefit from this test, especially if these changes have lasted for several weeks. For example, a person who has recently experienced unexplained weight gain, hair thinning, and trouble sleeping may find answers through this type of testing.
Ordering this test may also be helpful in these situations:
- Experiencing a drop in muscle mass or strength despite regular exercise.
- Dealing with low libido or changes in sexual function.
- Facing ongoing anxiety, mood swings, or irritability that do not improve with lifestyle changes.
- Having a family history of thyroid or hormone-related conditions.
- Noticing slow recovery from workouts, which can sometimes be linked to hormone or thyroid changes.
Testing these markers can help pinpoint the cause of symptoms like fatigue, low mood, or changes in body composition, making it easier to target the right treatment or lifestyle changes. Delaying this test could mean missing early signs of hormone or thyroid shifts, which may make symptoms harder to manage later.
How to Prepare for Hormone and Thyroid Marker Testing
Fasting is not required for this test, so you can eat and drink as usual before collecting your sample. Always follow any instructions your healthcare provider gives you to make sure your sample is collected correctly and your results are as useful as possible.
Labs Included When Ordering Your Male Serum Profile | ZRT Labs
| Test Name | Reference Range | What This Marker Means | Low and High Levels of This Marker |
|---|---|---|---|
| Estradiol (E2) | 10–40 | Estradiol is a form of estrogen important for bone strength, mood, and sexual function in men. It is produced from testosterone and helps balance other hormones. |
High levels mean there may be increased body fat, breast tissue growth, or mood changes.
Low levels mean there may be a risk for bone loss, joint pain, or low sex drive. |
| Testosterone | 300–1000 | Testosterone is the main male hormone that supports muscle mass, energy, mood, and sexual function. It also helps with bone strength and red blood cell production. |
High levels mean there may be acne, aggression, or risk for heart issues.
Low levels mean there may be fatigue, low muscle mass, or reduced sexual function. |
| Prostate-specific Antigen | 0–4 | Prostate-specific antigen (PSA) is a protein made by the prostate gland. It is used to monitor prostate health and screen for changes that may need further review. |
High levels mean there may be prostate inflammation, enlargement, or other prostate changes.
Low levels mean the prostate is likely healthy and not enlarged. |
| Cortisol x 2 | Morning: 6–18 Evening: 2–8 |
Cortisol is a hormone made by the adrenal glands that helps control stress, energy, and blood sugar. Testing at two times shows how your body handles stress throughout the day. |
High levels mean there may be ongoing stress, sleep problems, or high blood sugar.
Low levels mean there may be fatigue, low blood pressure, or trouble handling stress. |
| DHEAS | 80–560 | DHEAS is a hormone made by the adrenal glands that helps make testosterone and estrogen. It supports energy, mood, and immune function. |
High levels mean there may be excess hair growth, acne, or hormone imbalance.
Low levels mean there may be fatigue, low mood, or reduced muscle strength. |
| Sex Hormone Binding Globulin | 10–57 | Sex hormone binding globulin (SHBG) is a protein that carries testosterone and estrogen in the blood. It helps control how much of these hormones are available for the body to use. |
High levels mean less free testosterone is available, which can lower energy and sex drive.
Low levels mean more free testosterone is available, which can affect mood and body composition. |
| TSH | 0.4–4.5 | TSH (thyroid-stimulating hormone) tells the thyroid gland to make hormones that control metabolism, energy, and body temperature. It is a key marker for thyroid function. |
High levels mean the thyroid may be underactive, leading to tiredness or weight gain.
Low levels mean the thyroid may be overactive, causing restlessness or weight loss. |
| Free T3 | 2.3–4.2 | Free T3 is the active form of thyroid hormone that helps control how the body uses energy. It is important for mood, heart rate, and digestion. |
High levels mean there may be anxiety, fast heartbeat, or trouble sleeping.
Low levels mean there may be tiredness, slow thinking, or constipation. |
| Free T4 | 0.8–1.8 | Free T4 is a thyroid hormone that helps control metabolism and energy. It is converted into Free T3, the active form used by the body. |
High levels mean there may be restlessness, sweating, or weight loss.
Low levels mean there may be tiredness, dry skin, or weight gain. |
| TPO and Anti-TG Antibodies (Hashimoto’s Screen) | Negative | These antibodies show if the immune system is attacking the thyroid, which can lead to Hashimoto’s disease. Early detection helps prevent thyroid problems from getting worse. |
High levels mean there may be thyroid inflammation or risk for hypothyroidism.
Low levels mean the immune system is not attacking the thyroid. |
Reference ranges may change slightly as labs update their standards, so always check your report for the most current values.
Male Serum Profile FAQ
Is there Male Serum Profile testing near me?
This is a home test kit that you can collect locally, and you can check the draw location link at the top of the page for details. For those experiencing ongoing fatigue or hormone-related symptoms, having a nearby collection option makes it easier to get tested without extra travel or delays.
How do I interpret the test results?
While your treating physician should review your results, we also offer a one-on-one test results review with our clinical team to help you understand your results and next steps.
What is the cost of the test?
The price listed for this test includes standard shipping to you and return shipping to the lab, though draw fees may apply. Ordering this test can help you address hormone or thyroid symptoms sooner, which may help you feel better faster.
How often should I retest?
Retesting is usually recommended every 6 to 12 months, or as your symptoms or treatment plan changes, to track hormone and thyroid levels over time and adjust your care as needed.
How accurate is the test?
This test uses high-sensitivity immunoassay and chemiluminescence methods, with specificity and sensitivity both above 98%. TrueHealthLabs.com works with CLIA-certified and CAP-certified labs to maintain high-quality testing standards you can trust.
Important Notes
- This test CAN be shipped to and collected in the state of New York.
Medical Review Board
Reviewed by Jeff Donohue M.D. from Body Logic and Brady Hurst DC, CCCN. Written by True Health Lab’s team of editorial health contributors.
Disclaimer: This information is for educational purposes only and not intended as medical advice. Consult your healthcare provider for personalized guidance.
Why Customers Trust True Health Labs - What People are saying
Also rated 4.6 out of 5 based on 3452 ShopperApproved reviews- See all TrueHealthLabs.com reviews.
