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Lyme Urine Panel | Lyme Dot + PCR


  • Draw Locations
  • Processed by IGeneX
  • Turnaround Time: 5-8 Business Days on Average. Time may vary.
  • Not Available in: NY
  • HSA and FSA Approved

$629.00 USD $1149.00

100% interest free financing + no late fees
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Ordering the Lyme Urine Panel | Lyme Dot + PCR

Ordering the Lyme Urine Panel | Lyme Dot + PCR helps detect Lyme disease by identifying both antibodies and genetic material from Borrelia bacteria in urine samples. This test is especially useful for people who have ongoing symptoms that may not show up on standard blood tests. Interestingly, urine-based Lyme testing can sometimes detect infections that are missed by blood tests, especially in cases where the immune response is weak or delayed.

When ordering this test, you gain access to several specific benefits:

  • Detects both early and late-stage Lyme disease by measuring IgG and IgM antibodies and Borrelia DNA.
  • Non-invasive urine collection makes sample gathering easier and less stressful.
  • Can identify Lyme infection even when blood tests are inconclusive or negative.
  • Helps track the effectiveness of treatment by monitoring changes in antibody and DNA levels.
  • Provides results within 7 to 10 business days for timely follow-up with your healthcare provider.

Who Should Consider Lyme Disease Urine Testing

People who have unexplained joint pain, fatigue, or neurological symptoms after spending time in wooded or grassy areas may benefit from this test. For example, someone who enjoys hiking and later develops persistent headaches, muscle aches, and memory issues might want to check for Lyme disease, especially if they recall a tick bite or rash.

Ordering this test may also be helpful in these situations:

  • Unexplained facial palsy or sudden hearing loss after outdoor activities.
  • Chronic flu-like symptoms that do not improve with standard treatments.
  • Swollen lymph nodes and skin lesions following a camping trip.
  • Heart rhythm changes or chest discomfort with a history of tick exposure.
  • Unusual sleep disturbances or cognitive decline in children after summer camp, which can sometimes be linked to undiagnosed Lyme infection.

This test can help confirm or rule out Lyme disease, allowing for targeted treatment and monitoring. Delaying this test may allow symptoms to progress, making it harder to manage the infection and its effects.

Preparing for Urine-Based Lyme Disease Testing

Fasting is not required for this urine-based Lyme disease test, so you can eat and drink as usual before collecting your sample. Always follow any instructions your doctor or healthcare provider gives you to make sure your sample is collected and shipped correctly for the best results.

Labs Included When Ordering Your Lyme Urine Panel | Lyme Dot + PCR

Test Name Reference Range What the Test Measures Low and High Levels of Lyme Urine Panel | Lyme Dot + PCR
Lyme Dot Assay (3 sample) Negative This test checks for IgG and IgM antibodies against Borrelia bacteria in urine, which can indicate an active or past Lyme infection. It is useful for detecting both early and late stages of Lyme disease. High levels mean your body is producing antibodies to Borrelia, suggesting current or past Lyme infection.

Low levels mean there is little or no antibody response, which may indicate no infection or very early exposure.

PCR (pooled samples) Not detected PCR testing looks for Borrelia DNA in urine, confirming the presence of the bacteria itself. This method can detect Lyme even when antibodies are not yet present. High levels mean Borrelia DNA is present, confirming an active Lyme infection.

Low levels mean no Borrelia DNA was found, suggesting no current infection.

Reference ranges may be updated periodically as new research and guidelines become available. Always review your results with your healthcare provider for the most accurate interpretation.


Lyme Urine Panel | Lyme Dot + PCR FAQ

Is there Lyme Urine Panel | Lyme Dot + PCR testing near me?

This is a home test kit, so you can collect your urine sample locally and send it to the lab using the included shipping materials. For people experiencing symptoms like joint pain or brain fog, having a convenient collection option helps avoid travel and makes it easier to get tested quickly—check the draw location link at the top of the page for more details.

How do I interpret the test results?

While your treating physician should review your results, you can also use our one-on-one test results review service with our clinical team for a detailed explanation and next steps.

What is the cost of the test?

The price shown includes standard shipping to your address and return shipping to the lab, but draw fees may apply. Ordering this test can help you identify Lyme infection sooner, which may lead to faster symptom relief and more effective treatment.

How often should I retest?

Retesting is usually recommended every 3 to 6 months if you have ongoing symptoms or are monitoring treatment progress. Regular testing helps track changes in antibody and DNA levels, making it easier to adjust your care plan as needed.

How accurate is the test?

This test uses both Lyme Dot Assay for IgG and IgM antibodies and PCR for Borrelia DNA, providing high sensitivity (95%) and specificity (98%) for Lyme detection. TrueHealthLabs.com partners with CLIA-certified and CAP-certified laboratories to uphold rigorous testing standards for dependable results.


Medical Review Board

Reviewed by Jeff Donohue M.D. from Body Logic and Brady Hurst DC, CCCN. Written by True Health Lab’s team of editorial health contributors.

Disclaimer: This information is for educational purposes only and not intended as medical advice. Consult your healthcare provider for personalized guidance.


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