Ordering the IgG and IgM Antibody for Anaplasma Phagocytophila
Testing for IgG and IgM antibodies to Anaplasma phagocytophila helps identify if your immune system has responded to this tick-borne bacteria, which can cause symptoms like fever, chills, muscle pain, and low platelets. Interestingly, early detection of both IgG and IgM antibodies can help distinguish between a recent and a past infection, which is especially useful for people who may have been exposed to ticks during peak season.
Ordering this test provides several specific benefits:
- Detects both recent and past exposure to Anaplasma phagocytophila.
- Helps guide treatment decisions for tick-borne illnesses.
- Supports diagnosis when symptoms overlap with other infections like Lyme disease or ehrlichiosis.
- Assists in monitoring response to treatment over time.
- Can be used to evaluate possible co-infections in people with persistent symptoms.
Who Should Consider Antibody Testing for Tick-Borne Infections
People who have spent time outdoors in wooded or grassy areas and later develop unexplained fever, fatigue, or joint pain may benefit from this test. For example, someone who enjoys hiking and notices ongoing muscle aches and headaches after a tick bite may want to check for antibodies to Anaplasma phagocytophila.
Ordering this test may also be helpful in these situations:
- After a known tick bite, especially during tick season.
- When symptoms like chills, nausea, or rash appear without a clear cause.
- If you have low white blood cells or platelets on a recent blood test.
- When you have been diagnosed with another tick-borne illness, such as Lyme disease, and symptoms persist.
- Following unexplained confusion or dizziness after outdoor activities, as these can sometimes be linked to tick-borne infections.
Testing for these antibodies can help pinpoint the cause of symptoms and guide the next steps for care, especially when symptoms overlap with other conditions. Delaying this test may make it harder to identify the infection early, which could affect how quickly you start the right treatment.
Preparing for Tick-Borne Disease Antibody Testing
Fasting is not required before this test, so you can eat and drink as usual. Make sure to carefully follow any instructions your doctor or healthcare provider gives you to ensure your sample is collected correctly and processed without delay.
Labs Included When Ordering Your IgG and IgM Antibody for Anaplasma Phagocytophila
| Test Name | Reference Range | What This Biomarker Means | Low and High Levels of IgG and IgM Antibody for Anaplasma Phagocytophila |
|---|---|---|---|
| Anaplasma phagocytophila IgG Antibody | Negative: <1:40 Equivocal: 1:40 Positive: >1:40 |
This marker shows if your immune system has produced IgG antibodies to Anaplasma phagocytophila, which usually appear weeks after infection. IgG levels can help determine if you have had a past or ongoing infection. |
High levels mean your body has likely been exposed to Anaplasma phagocytophila in the past or has a current infection.
Low levels mean there is no evidence of past exposure or infection. |
| Anaplasma phagocytophila IgM Antibody | Negative: <1:20 Equivocal: 1:20 Positive: >1:20 |
This marker detects IgM antibodies, which are usually the first to appear after infection with Anaplasma phagocytophila. IgM levels help identify recent or active infection. |
High levels mean a recent or current infection with Anaplasma phagocytophila is likely.
Low levels mean there is no sign of a recent infection. |
Reference ranges may change slightly as labs update their methods and standards. Always check your report for the most current information.
IgG and IgM Antibody for Anaplasma Phagocytophila FAQ
Is there IgG and IgM Antibody for Anaplasma Phagocytophila testing near me?
This test is provided as a kit that you can use at a local draw site—see the draw location link at the top of the page. Because symptoms like fever and joint pain can make travel difficult, having a nearby collection option makes it easier to get tested quickly and comfortably.
How do I interpret the test results?
While your treating physician should review your results, you can also schedule a one-on-one test results review with our clinical team for clear, personalized guidance.
What is the cost of the test?
The price you see includes standard shipping to you and return shipping to the lab, though draw fees may apply at your chosen collection site. Ordering this test can help you identify a tick-borne infection sooner, which may help you start treatment and feel better faster.
How often should I retest?
Retesting is usually recommended 2–4 weeks after the first test if symptoms continue or if your doctor wants to monitor changes in antibody levels. Repeating the test can help track your immune response and guide treatment decisions.
How accurate is the test?
This test uses an indirect immunofluorescence assay (IFA) method, with a sensitivity of 94% and specificity of 98% for detecting Anaplasma phagocytophila antibodies. TrueHealthLabs.com partners with CLIA-certified and CAP-certified laboratories to uphold rigorous testing standards for dependable results.
Important Notes
None.
Medical Review Board
Reviewed by Jeff Donohue M.D. from Body Logic and Brady Hurst DC, CCCN. Written by True Health Lab’s team of editorial health contributors.
Disclaimer: This information is for educational purposes only and not intended as medical advice. Consult your healthcare provider for personalized guidance.
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