Ordering the HDL Map Test by Boston Heart
The HDL Map Test by Boston Heart helps measure different types of cholesterol in your blood, giving a detailed look at your risk for heart and artery problems. This test breaks down high-density lipoproteins (HDL) into subgroups, which can help your doctor see how well your body is managing cholesterol and if you might be at risk for plaque buildup in your arteries. Interestingly, research shows that not all HDL is equally protective—some subtypes are more helpful than others in lowering the risk of heart attack and stroke.
Ordering the HDL Map Test can provide you with:
- A breakdown of your HDL cholesterol into five subtypes for a more complete heart risk profile
- Information to help your doctor create a more targeted plan for lowering your risk of heart disease
- Early detection of changes in your cholesterol that standard tests may miss
- Guidance for adjusting your diet, exercise, or other habits based on your specific cholesterol patterns
- Support for tracking how well your current treatment or lifestyle changes are working
Who Should Consider Advanced Cholesterol Subtype Testing
Someone who has a family history of heart disease but normal cholesterol numbers might wonder if they are still at risk. This test can help uncover hidden risks by looking at the different types of HDL cholesterol, which standard tests do not show.
Ordering this test may also be helpful if you:
- Have a personal or family history of early heart attack or stroke
- Have diabetes, metabolic syndrome, or high triglycerides
- Are overweight or have high blood pressure despite normal cholesterol levels
- Are following a special diet or exercise plan and want to see if it is improving your cholesterol subtypes
- Have chronic inflammation or autoimmune conditions, as these can affect cholesterol patterns in unexpected ways
This test is a good choice for people who want to know if their cholesterol is truly protective or if there are hidden risks that need attention. Delaying this test could mean missing early signs of artery plaque buildup, which can be managed more easily when found sooner.
Preparing for Your HDL Subclass Analysis
Fasting for 12 hours before your blood draw is required for the most accurate results from this test. Always follow any instructions your doctor or healthcare provider gives you to make sure your sample is collected correctly and your results are as useful as possible.
Labs Included When Ordering Your HDL Map Test
| Test Name | Reference Range | What This Measures | Low and High Levels of HDL Map Test |
|---|---|---|---|
| α-1 HDL | >30% | α-1 HDL is the largest and most protective HDL particle. It helps remove cholesterol from artery walls and lowers the risk of plaque buildup. |
High levels mean your body is efficiently clearing cholesterol from your arteries.
Low levels mean you may have a higher risk for heart disease and less protection against artery plaque. |
| α-2 HDL | 15-25% | α-2 HDL is a medium-sized HDL particle that helps transport cholesterol to the liver for removal. It supports healthy cholesterol balance. |
High levels mean your cholesterol transport system is working well.
Low levels mean your body may not be moving cholesterol out of your blood as effectively. |
| α-3 HDL | 10-20% | α-3 HDL is a smaller HDL particle that plays a role in cholesterol removal but is less protective than α-1 and α-2. |
High levels mean your body is producing more small HDL particles, which may not be as protective.
Low levels mean you have fewer small HDL particles, which is usually not a concern if α-1 and α-2 are normal. |
| α-4 HDL | <5% | α-4 HDL is a very small HDL particle. High levels may be linked to less effective cholesterol removal and higher risk for artery problems. |
High levels mean your HDL may not be working as well to protect your arteries.
Low levels mean your HDL profile is more likely to be protective. |
| Preβ-1 HDL | <7% | Preβ-1 HDL is the smallest HDL particle and is the first step in cholesterol removal. High levels may mean your body is struggling to process cholesterol efficiently. |
High levels mean your body may not be moving cholesterol through the normal pathway, which can increase risk for artery plaque.
Low levels mean your cholesterol removal process is likely working well. |
Reference ranges may change slightly as labs update their methods and guidelines.
HDL Map Test FAQ
Is there HDL Map Test testing near me?
This test is available as a kit that you can take to a local blood draw site—check the draw location link above for options. If you need to monitor your cholesterol subtypes regularly or have trouble traveling far, having a nearby collection site makes it easier to stay on top of your heart risk.
How do I interpret the test results?
While your doctor should review your results with you, we also offer a one-on-one test results review with our clinical team to help you understand your numbers and what they mean for your heart and arteries.
What is the cost of the test?
The price you see for the test includes standard shipping to your address and return shipping to the lab, but local draw fees may apply. Ordering this test can help you find hidden cholesterol risks, so you and your doctor can make changes that may help you avoid future heart problems.
How often should I retest?
Most people should repeat this test every 6 to 12 months, especially if they are making changes to their diet, exercise, or treatment plan. Regular retesting helps track how your cholesterol subtypes respond, so you can see if your risk for artery plaque is going up or down.
How accurate is the test?
The HDL Map Test uses high-resolution gel electrophoresis to separate and measure HDL subtypes, with a specificity of 98% and sensitivity of 97%. TrueHealthLabs.com partners with CLIA-certified and CAP-certified laboratories to uphold rigorous testing standards for dependable results.
Important Notes
- This test is not available in New York.
Medical Review Board
Reviewed by Jeff Donohue M.D. from Body Logic and Brady Hurst DC, CCCN. Written by True Health Lab’s team of editorial health contributors.
Disclaimer: This information is for educational purposes only and not intended as medical advice. Consult your healthcare provider for personalized guidance.
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