Ordering the Comprehensive Female Profile 2 | ZRT Labs
Ordering the Comprehensive Female Profile 2 from ZRT Labs helps you check hormone and thyroid levels, as well as vitamin D and adrenal function, all from home. This test uses both saliva and blood spot samples to measure key markers linked to symptoms like fatigue, mood changes, irregular periods, and weight gain. Interestingly, testing cortisol at four different times in one day can reveal hidden patterns of adrenal stress that single-sample tests might miss.
When ordering this test, you can expect these specific benefits:
- Measures cortisol at four points in the day to show daily stress patterns
- Checks thyroid markers, including TSH, Free T3, Free T4, and thyroid antibodies for a full thyroid picture
- Assesses estrogen, progesterone, and testosterone to help pinpoint hormone imbalances
- Includes vitamin D and DHEAS to support bone and immune function
- Uses a simple home collection kit for both saliva and blood spot samples
Who Should Consider Hormone and Thyroid Panel Testing
People who have been feeling tired, dealing with mood swings, or noticing changes in their menstrual cycle may benefit from this test. For example, someone who has been struggling with low energy, trouble sleeping, and hair loss for months might find answers by checking their hormone and thyroid levels.
Ordering this test may also be helpful in these situations:
- Experiencing hot flashes or night sweats during menopause
- Having trouble getting pregnant despite regular cycles
- Dealing with unexplained weight gain or difficulty losing weight
- Noticing new or worsening anxiety, depression, or irritability
- Finding that your skin bruises more easily, which can be linked to cortisol imbalance
Testing these markers can help you and your doctor find the cause of symptoms like fatigue, mood changes, or irregular periods, and guide treatment for hormone or thyroid imbalances. Delaying this test could mean missing early signs of hormone or thyroid changes, which may make symptoms harder to manage later.
Preparing for Your At-Home Hormone and Thyroid Test
Fasting is not required for this test, so you can eat and drink as usual before collecting your samples. Always follow any instructions your doctor or healthcare provider gives you to make sure your samples are collected at the right times and in the correct way.
Labs Included When Ordering Your Comprehensive Female Profile 2
| Test Name | Reference Range | What This Test Shows | Low and High Levels of This Marker |
|---|---|---|---|
| Saliva Markers | |||
| Cortisol (Morning) | 3.7–9.5 ng/mL | This shows how your body responds to stress when you wake up. Morning cortisol should be at its highest to help you start your day. |
High levels mean your body may be under stress or you may have adrenal overactivity.
Low levels mean your adrenal glands may not be making enough cortisol, which can cause tiredness. |
| Cortisol (Noon) | 1.2–3.0 ng/mL | This measures how your stress hormone drops as the day goes on. Noon levels should be lower than morning but still in range. |
High levels mean ongoing stress or possible adrenal imbalance.
Low levels mean your energy may dip too early in the day. |
| Cortisol (Evening) | 0.6–1.9 ng/mL | This shows if your body is winding down in the evening. Evening cortisol should be low to help you relax and prepare for sleep. |
High levels mean you may have trouble falling asleep or feel wired at night.
Low levels mean your body may be overly tired or sluggish in the evening. |
| Cortisol (Midnight) | 0.4–1.0 ng/mL | This checks if your stress hormone is lowest at night, which is needed for restful sleep. Midnight cortisol should be at its lowest point. |
High levels mean you may wake up at night or have poor sleep quality.
Low levels mean your adrenal glands are resting as expected. |
| Blood Spot Markers | |||
| TSH | 0.45–4.5 mIU/L | TSH, or thyroid stimulating hormone, shows how well your thyroid is working. It helps control your body’s energy and metabolism. |
High levels mean your thyroid may be underactive (hypothyroidism).
Low levels mean your thyroid may be overactive (hyperthyroidism). |
| Free T3 | 2.0–4.4 pg/mL | Free T3 is the active form of thyroid hormone. It helps control how your body uses energy and keeps your metabolism steady. |
High levels mean your thyroid is making too much hormone.
Low levels mean your body may not be getting enough thyroid hormone. |
| Free T4 | 0.8–1.8 ng/dL | Free T4 is another thyroid hormone that helps control energy and metabolism. It is converted into Free T3 in your body. |
High levels mean your thyroid is overactive.
Low levels mean your thyroid is underactive. |
| TPO and Anti-TG Antibodies | <9 IU/mL (TPO), <4 IU/mL (Anti-TG) | These antibodies show if your immune system is attacking your thyroid, which can cause thyroid problems like Hashimoto’s disease. |
High levels mean possible autoimmune thyroid disease.
Low levels mean your immune system is not attacking your thyroid. |
| Estradiol | 19–160 pg/mL (premenopausal), <40 pg/mL (postmenopausal) | Estradiol is the main estrogen in women. It helps control periods, bone strength, and mood. |
High levels mean possible estrogen dominance or hormone imbalance.
Low levels mean possible menopause or low estrogen symptoms. |
| Progesterone | 75–270 pg/mL (luteal phase), <40 pg/mL (follicular phase) | Progesterone helps balance estrogen and supports regular periods and pregnancy. It also helps with sleep and mood. |
High levels mean possible pregnancy or hormone therapy.
Low levels mean possible PMS, irregular periods, or trouble getting pregnant. |
| Testosterone | 16–55 ng/dL (female) | Testosterone supports muscle strength, mood, and sex drive in women. It is important for energy and bone health. |
High levels mean possible PCOS or excess hair growth.
Low levels mean low energy, low sex drive, or muscle weakness. |
| Sex Hormone Binding Globulin | 18–114 nmol/L | This protein carries hormones like estrogen and testosterone in your blood. It helps control how much hormone is available to your body. |
High levels mean less free hormone is available.
Low levels mean more free hormone is available, which can cause symptoms. |
| DHEAS | 35–430 µg/dL (female) | DHEAS is made by your adrenal glands and helps make other hormones. It supports energy, mood, and bone strength. |
High levels mean possible adrenal overactivity or PCOS.
Low levels mean possible adrenal fatigue or low hormone production. |
Reference ranges may change slightly as labs update their standards, so always check your report for the most current values.
Comprehensive Female Profile 2 FAQ
Is there Comprehensive Female Profile 2 testing near me?
This is a home test kit, so you can collect your saliva and blood spot samples locally and send them to the lab. For those experiencing symptoms like fatigue or irregular periods, having a convenient collection option means you don’t have to wait for a clinic appointment or travel far to get tested.
How do I interpret the test results?
While your doctor should review your results, we also offer a one-on-one test results review with our clinical team to help you understand what your numbers mean and what steps you can take next.
What is the cost of the test?
The price you see for this test includes standard shipping to your address and return shipping to the lab, but local draw fees may apply. Ordering this test can help you find the cause of symptoms like fatigue or mood changes, so you can start feeling better sooner.
How often should I retest?
It’s best to retest every 3 to 6 months, especially if you are starting a new treatment or making changes to your routine, so you can track how your hormone and thyroid levels respond over time.
How accurate is the test?
This test uses saliva and blood spot collection, analyzed by liquid chromatography-tandem mass spectrometry (LC-MS/MS) and immunoassay methods, with specificity and sensitivity both above 95%. TrueHealthLabs.com partners with CLIA-certified and CAP-certified laboratories to uphold rigorous testing standards for dependable results.
Medical Review Board
Reviewed by Jeff Donohue M.D. from Body Logic and Brady Hurst DC, CCCN. Written by True Health Lab’s team of editorial health contributors.
Disclaimer: This information is for educational purposes only and not intended as medical advice. Consult your healthcare provider for personalized guidance.
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