Ordering the Complete Lyme Panel | IB3
The Complete Lyme Panel | IB3 helps detect Lyme disease and related infections by measuring specific immune responses and identifying the presence of Lyme bacteria in the blood. This test is often used when symptoms such as joint pain, fatigue, or neurological changes persist without a clear cause. Interestingly, some people may not develop the classic bullseye rash after a tick bite, making lab testing a key step in finding answers.
Ordering this test can provide:
- Detection of both early and late Lyme disease markers
- Identification of immune system response through IgG, IgM, and IgA antibodies
- Direct detection of Lyme bacteria DNA using PCR technology
- Support for diagnosis when symptoms are unclear or overlap with other conditions
- Guidance for targeted treatment and follow-up care
Who Should Consider Comprehensive Tick-Borne Infection Testing
People who have experienced unexplained joint pain, memory problems, or fatigue after spending time outdoors in areas where ticks are common may benefit from this test. For example, someone who enjoys hiking and later develops headaches, muscle aches, and trouble concentrating might use this test to check for Lyme and related infections.
Ordering this test may also be helpful in these situations:
- Persistent flu-like symptoms after a known tick bite
- Unexplained facial palsy or sudden hearing changes
- Recurring skin rashes that do not respond to standard treatments
- Swollen lymph nodes with no clear infection source
- Eye inflammation that appears weeks after outdoor activities
Testing can help pinpoint the cause of symptoms by measuring specific antibodies and bacterial DNA, which can lead to more precise treatment. Delaying this test may allow symptoms to progress, making it harder to identify the infection and start the right treatment.
How to Prepare for Tick-Borne Disease Blood Testing
Fasting is not required before this test, so you can eat and drink as usual. Always follow any instructions your doctor or healthcare provider gives you to make sure your sample is collected correctly and your results are as useful as possible.
Labs Included When Ordering Your Complete Lyme Panel | IB3
| Test Name | Reference Range | What This Test Measures | Low and High Levels of Complete Lyme Panel | IB3 |
|---|---|---|---|
| ImmunoBlot IgG | Negative: <1.0 Positive: ≥1.0 |
This test checks for IgG antibodies, which show if your immune system has responded to Lyme bacteria over time. It helps identify past or ongoing infection. |
High levels mean your body has likely been exposed to Lyme bacteria for a longer period.
Low levels mean there is little or no evidence of a long-term immune response to Lyme. |
| ImmunoBlot IgM | Negative: <1.0 Positive: ≥1.0 |
This test looks for IgM antibodies, which are usually produced early after infection. It helps detect recent or active Lyme disease. |
High levels mean a recent or current infection with Lyme bacteria is likely.
Low levels mean there is little or no evidence of a recent immune response to Lyme. |
| Lyme IgG/IgM/IgA Screen | Negative: <1.0 Equivocal: 0.91–1.09 Positive: ≥1.10 |
This screening test checks for three types of antibodies (IgG, IgM, IgA) to give a broad view of your immune response to Lyme bacteria. |
High levels mean your immune system is actively responding to Lyme bacteria.
Low levels mean there is little or no immune response detected for Lyme. |
| Lyme PCR, Serum | Negative: Not detected Positive: Detected |
This test looks for the genetic material (DNA) of Lyme bacteria in your blood, which can confirm an active infection. |
High levels mean Lyme bacteria DNA is present, showing an active infection.
Low levels mean no Lyme bacteria DNA was found in your blood. |
Reference ranges may change slightly as labs update their methods and standards.
Complete Lyme Panel | IB3 FAQ
Is there Complete Lyme Panel | IB3 testing near me?
This is a test kit that can be collected at a local draw site; check the draw location link at the top of the page. For people dealing with symptoms like joint pain or memory issues, having a nearby collection site makes it easier to get tested quickly and start finding answers.
How do I interpret the test results?
While your treating physician should review your results, you can also use our one-on-one test results review service with our clinical team for a detailed explanation and next steps.
What is the cost of the test?
The price for this test includes standard shipping to you and return shipping to the lab, but draw fees may apply. Ordering this test can help you identify the cause of symptoms like fatigue or joint pain, so you can start the right treatment sooner.
How often should I retest?
Retesting is usually recommended every 3 to 6 months if symptoms continue or if you are being treated for Lyme disease. Regular testing helps track changes in your immune response and can show if treatment is working.
How accurate is the test?
This panel uses ImmunoBlot and PCR methods, which are known for high sensitivity (up to 98%) and specificity (up to 99%) in detecting Lyme antibodies and DNA. TrueHealthLabs.com partners with CLIA-certified and CAP-certified laboratories to uphold rigorous testing standards for dependable results.
Important Notes
None.
Medical Review Board
Reviewed by Jeff Donohue M.D. from Body Logic and Brady Hurst DC, CCCN. Written by True Health Lab’s team of editorial health contributors.
Disclaimer: This information is for educational purposes only and not intended as medical advice. Consult your healthcare provider for personalized guidance.
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