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AQP4, NMO-IgG Antibody with Reflex to Titer Test


  • Draw Locations
  • Turnaround Time: 10-14 Business Days
  • Not Available in: NY, NJ, MA, and RI
  • HSA and FSA Approved

$859.00 USD $1345.00

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Understanding the Aquaporin-4 IgG Antibody Test

The Aquaporin-4 IgG Antibody Test is a specialized blood test that helps detect antibodies associated with neuromyelitis optica, a rare autoimmune disorder. This test is important because it aids in distinguishing NMO from other similar neurological conditions, ensuring accurate diagnosis and treatment.

Interestingly, this test can sometimes reveal the presence of antibodies even before symptoms appear, offering a proactive approach to managing health.

  • Helps differentiate between NMO and multiple sclerosis.
  • Can guide treatment decisions and monitor disease progression.
  • Provides peace of mind by confirming or ruling out NMO.

Who Might Benefit from This Test?

Individuals experiencing unexplained neurological issues or those with a family history of autoimmune disorders may find this test beneficial. Consider this test if you’re seeking clarity on your health status and want to take control of your condition.

Think about the relief of finally understanding what’s happening in your body, allowing you to make informed decisions about your health.

Here are some scenarios where this test might be considered:

  • Persistent vision problems without a clear cause.
  • Recurrent episodes of muscle weakness.
  • Unexplained numbness or tingling in limbs.
  • Family history of neuromyelitis optica.
  • Unusual fatigue that doesn’t improve with rest.

Consider ordering the test if any of these situations apply to you.

Preparing for the Antibody Test

Preparing for the Aquaporin-4 IgG Antibody Test is simple. No fasting is required, so you can eat and drink as usual. If you are taking supplements or medications, follow the instructions provided by your doctor tailored to your specific health situation.

Labs Included When Ordering Your Aquaporin-4 IgG Antibody Test

Test Name Reference Range Significance Low and High Levels
Aquaporin 4 Ab, CBA Negative This biomarker helps identify the presence of antibodies linked to neuromyelitis optica. Detecting these antibodies is crucial for distinguishing NMO from other neurological disorders. High: High levels of Aquaporin 4 Ab, CBA may indicate the presence of neuromyelitis optica spectrum disorder.

Low: Low levels of Aquaporin 4 Ab, CBA are typically considered normal and suggest the absence of NMO-related antibodies.

Reference ranges can vary. For the most accurate and up-to-date reference ranges for this lab test, visit Quest Diagnostics.


Aquaporin-4 IgG Antibody Test FAQ

Is there Aquaporin-4 IgG Antibody Test testing near me?

You can find nearby draw locations for the Aquaporin-4 IgG Antibody Test with our patient service center locator + mobile phlebotomy.

What is the cost of the test?

The cost of the Aquaporin-4 IgG Antibody Test can be found at the top of the page. Pricing includes draw fees when visiting patient service centers.

How often should I retest?

Retesting is generally recommended every 6 to 12 months, depending on your health status and in consultation with your healthcare provider.

How accurate is the test?

TrueHealthLabs.com only partners with CLIA certified labs, ensuring the highest standards of accuracy and reliability for your test results.


Medical Review Board

Reviewed by Jeff Donohue M.D. from Body Logic and Brady Hurst DC, CCCN. Written by True Health Lab’s team of editorial health contributors.

Disclaimer: This information is for educational purposes only and not intended as medical advice. Consult your healthcare provider for personalized guidance.


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