Ordering the Anaplasma Phagocytophila PCR
Anaplasma Phagocytophila PCR is a molecular test that detects the DNA of Anaplasma phagocytophilum, a bacteria spread by ticks and known to cause anaplasmosis. This test is often ordered to help confirm infection in people with symptoms like fever, chills, muscle aches, and low white blood cell counts, especially after a tick bite. Interestingly, this PCR test can identify the bacteria even before antibodies are present, making it useful in the early stages of infection.
Ordering this test can help you:
- Detect Anaplasma phagocytophilum DNA in the blood during the first days of symptoms
- Distinguish anaplasmosis from other tick-borne diseases like Lyme or babesiosis
- Guide your doctor in choosing the right treatment quickly
- Monitor response to therapy if symptoms persist
- Reduce the risk of complications by confirming infection early
Who Should Consider Tick-Borne Disease PCR Testing
People who have recently spent time in wooded or grassy areas and develop sudden fever, headache, or muscle pain may benefit from this test, especially if they notice a tick bite or develop symptoms soon after outdoor activities. For example, someone who enjoys hiking and starts feeling unusually tired and feverish a week later may want to order this test to check for tick-borne infections.
Ordering may also be helpful in these situations:
- Unexplained drop in white blood cells or platelets after outdoor exposure
- Persistent flu-like symptoms that do not improve with standard care
- History of tick bites in areas where anaplasmosis is common
- Joint pain and night sweats following a camping trip
- Unusual confusion or dizziness in someone with recent tick exposure, as neurological symptoms can sometimes be linked to this infection
Testing for this infection can help confirm the cause of symptoms, guide treatment, and prevent further complications like severe anemia or organ involvement. Delaying this test may make it harder to detect the bacteria, especially if antibiotics are started before testing.
How to Prepare for the Test
Fasting is not needed for this test, so you can eat and drink as usual before your blood sample is collected. Always follow any instructions your doctor or healthcare provider gives you to make sure your sample is collected and processed correctly.
Labs Included When Ordering Your Anaplasma Phagocytophila PCR
| Test Name | Reference Range | Significance | Low and High Levels of Anaplasma Phagocytophila PCR |
|---|---|---|---|
| Anaplasma phagocytophilum DNA (PCR) | Not detected | This test looks for the genetic material of Anaplasma phagocytophilum in your blood. A positive result means the bacteria is present and active in your body. |
High levels mean the bacteria is present and you likely have an active infection.
Low levels mean the bacteria was not found in your blood at the time of testing. |
Reference ranges may change slightly as labs update their methods and standards.
Anaplasma Phagocytophila PCR FAQ
Is there Anaplasma Phagocytophila PCR testing near me?
This is a test kit that can be collected at a local draw site—see the draw location link at the top of the page. Since symptoms like fever and fatigue can appear quickly after a tick bite, having a nearby collection site makes it easier to get tested without delay.
How do I interpret the test results?
While your treating physician should review your results, we also offer a one-on-one test results review with our clinical team to help you understand what your results mean and what steps to take next.
What is the cost of the test?
The price you see includes standard shipping to you and back to the lab, but local draw fees may apply. Ordering this test can help you find out if a tick-borne infection is causing your symptoms, so you can start the right treatment sooner.
How often should I retest?
Retesting is usually recommended if symptoms return or if your doctor wants to check if the infection has cleared, often within 2-4 weeks after treatment. Repeating the test can help confirm that the bacteria is no longer present in your blood.
How accurate is the test?
This test uses polymerase chain reaction (PCR) to detect Anaplasma phagocytophilum DNA, with a sensitivity of 95% and specificity of 98%. TrueHealthLabs.com partners with CLIA-certified and CAP-certified laboratories to uphold rigorous testing standards for dependable results.
Medical Review Board
Reviewed by Jeff Donohue M.D. from Body Logic and Brady Hurst DC, CCCN. Written by True Health Lab’s team of editorial health contributors.
Disclaimer: This information is for educational purposes only and not intended as medical advice. Consult your healthcare provider for personalized guidance.
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