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TBRF ImmunoBlot IgG


  • Draw Locations
  • Processed by IgeneX
  • Turnaround Time: 5-8 Business Days on Average. Time may vary.
  • Not Available in: NY
  • HSA and FSA Approved

$379.00 USD $790.00

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Ordering the TBRF ImmunoBlot IgG

The TBRF ImmunoBlot IgG test helps detect antibodies to tick-borne relapsing fever (TBRF) Borrelia species, which can cause recurring fever, fatigue, and neurological symptoms. This test is especially useful for people who have unexplained symptoms after possible tick exposure, as TBRF can be missed by standard Lyme disease tests. Interestingly, TBRF Borrelia species are different from those that cause Lyme disease, so a separate test is needed for accurate detection.

Ordering this test can help you:

  • Identify if your symptoms are linked to TBRF Borrelia infection, even if Lyme disease tests are negative.
  • Support your healthcare provider in making a more targeted treatment plan.
  • Track your immune response to TBRF Borrelia over time.
  • Rule out other causes of recurring fever and neurological symptoms.
  • Access specialized testing not available in standard labs.

Who Should Consider Tick-Borne Relapsing Fever Antibody Testing

People who have experienced recurring fever, fatigue, and neurological symptoms after spending time in areas where ticks are common may benefit from this test. For example, someone who has ongoing headaches, memory problems, and joint pain after a camping trip in a region known for tick activity may want to check for TBRF Borrelia infection.

Ordering this test may also be helpful in these situations:

  • Unexplained night sweats and chills that come and go.
  • Persistent dizziness, mood swings, or concentration issues after a tick bite.
  • Eye pain, neck stiffness, or sensitivity to light with no clear cause.
  • Swollen lymph nodes and muscle aches that do not improve with standard care.
  • Someone who has a rash that appears and disappears, especially if it is not the classic Lyme disease rash.

Testing for TBRF Borrelia can help pinpoint the cause of recurring symptoms, allowing for more specific treatment and monitoring. Delaying this test may result in ongoing symptoms that could be addressed sooner with the right diagnosis.

Preparing for Your TBRF Antibody Blood Test

Fasting is not required for the TBRF ImmunoBlot IgG test, so you can eat and drink as usual before your blood draw. Always follow any instructions or special guidance provided by your doctor or healthcare provider to ensure your sample is collected correctly and your results are as useful as possible.

Labs Included When Ordering Your TBRF ImmunoBlot IgG

Test Name Reference Range What This Biomarker Means Low and High Levels of TBRF ImmunoBlot IgG
TBRF ImmunoBlot IgG Negative: < 1.0
Equivocal: 1.0–1.19
Positive: ≥ 1.2
This test measures IgG antibodies to tick-borne relapsing fever Borrelia species. A positive result shows your immune system has responded to these bacteria, which can cause recurring fever and neurological symptoms. High levels mean your body has produced IgG antibodies to TBRF Borrelia, suggesting current or past infection.

Low levels mean there is little or no IgG antibody response, making active or past infection less likely.

Reference ranges may change slightly as labs update their methods and standards.


TBRF ImmunoBlot FAQ

Is there TBRF ImmunoBlot testing near me?

This is a test kit that you can use for a local blood draw—check the draw location link at the top of the page for options. Because symptoms like recurring fever and fatigue can make travel difficult, having a nearby collection site makes it easier to get tested quickly and comfortably.

How do I interpret the test results?

While your treating physician should always review your results, we also offer a one-on-one test results review with our clinical team to help you understand what your results mean and what steps to consider next.

What is the cost of the test?

The price you see includes standard shipping to you and return shipping to the lab, but local draw fees may apply. Ordering this test can help you find answers for recurring symptoms, so you can start the right treatment sooner.

How often should I retest?

Retesting is usually recommended 4–6 weeks after treatment or if symptoms return, to check for changes in antibody levels. Repeating the test can help track your immune response and guide your next steps if symptoms persist.

How accurate is the test?

The TBRF ImmunoBlot IgG uses an immunoblot method to detect specific IgG antibodies to TBRF Borrelia, with a sensitivity of 98% and specificity of 98%. TrueHealthLabs.com partners with CLIA-certified and CAP-certified laboratories to uphold rigorous testing standards for dependable results.

Important Notes

Not available for residents of New York.


Medical Review Board

Reviewed by Jeff Donohue M.D. from Body Logic and Brady Hurst DC, CCCN. Written by True Health Lab’s team of editorial health contributors.

Disclaimer: This information is for educational purposes only and not intended as medical advice. Consult your healthcare provider for personalized guidance.


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