Ordering the Secretory Immunoglobulin A (sIgA) Test | Europe
Secretory Immunoglobulin A (sIgA) is a key antibody found in saliva and the lining of the gut, playing a direct role in the body’s first line of defense against bacteria, viruses, and allergens. This test helps identify imbalances that may be linked to digestive issues, food sensitivities, and immune system changes. Interestingly, sIgA levels can also reflect how chronic stress affects the immune system, making this test useful for those experiencing ongoing stress-related symptoms.
Ordering this test provides several specific benefits:
- Detects early signs of gut inflammation and mucosal damage.
- Helps pinpoint immune system imbalances related to allergies or chronic infections.
- Assists in monitoring the impact of stress on immune function.
- Supports targeted treatment plans for digestive discomfort and food reactions.
- Tracks progress in managing conditions like irritable bowel syndrome or leaky gut.
Who Should Consider Gut Immune Function Testing
People who have ongoing digestive discomfort, frequent colds, or unexplained fatigue may benefit from this test. For example, someone who has tried multiple diets and supplements for stomach pain but still feels unwell could use this test to find out if their immune system in the gut is involved.
Ordering this test may also be helpful in these situations:
- Recurring yeast or Candida infections that do not respond to standard treatments
- Unexplained mood changes, such as anxiety or depression, that seem linked to digestive symptoms
- Chronic sinus congestion or allergies that flare up after eating certain foods
- Long-term use of antibiotics with ongoing digestive upset
- Unexpectedly, people with skin rashes that worsen after stress or illness may find this test useful
Testing for sIgA can reveal if the immune system in the gut is overactive or underactive, which can help guide specific changes in diet or treatment. Delaying this test may allow ongoing immune imbalances to go unnoticed, making it harder to address symptoms effectively.
Preparing for Salivary Antibody and Gut Barrier Testing
Fasting is not required for this test, but it is best to collect the sample at the same time each day for consistency. Always follow the instructions provided by your doctor or healthcare practitioner to make sure your sample is collected and handled correctly.
Labs Included When Ordering Your Secretory Immunoglobulin A (sIgA) Test
| Test Name | Reference Range | What This Marker Means | Low and High Levels of Secretory Immunoglobulin A (sIgA) |
|---|---|---|---|
| Secretory Immunoglobulin A (sIgA) | 510 – 2040 | Secretory Immunoglobulin A is the main antibody in saliva and the gut lining, helping protect against bacteria, viruses, and allergens. It is a marker for mucosal immune activity and gut barrier function. |
High levels mean the immune system in the gut is reacting to infection, inflammation, or food sensitivities.
Low levels mean the gut’s immune defense may be weakened, making it harder to fight off infections or recover from stress. |
Reference ranges may change slightly as labs update their methods and guidelines.
Secretory Immunoglobulin A Test FAQ
Is there Secretory Immunoglobulin A testing near me?
This test is provided as a kit that you can use at home, and samples can be collected locally—check the draw location link at the top of the page. For those dealing with ongoing digestive or immune issues, having a nearby collection site makes it easier to get tested quickly and start finding answers.
How do I interpret the test results?
While your treating physician should review your results, we also offer a one-on-one test results review with our clinical team to help you understand what your numbers mean and what steps to take next.
What is the cost of the test?
The price listed for this test includes standard shipping to you and return shipping to the lab, though draw fees may apply. Ordering this test can help you address gut and immune symptoms sooner, which may speed up your recovery.
How often should I retest?
Retesting is usually recommended every 3 to 6 months, especially if you are making changes to your diet or treatment plan. This helps track your progress and shows if your gut immune function is improving or if further adjustments are needed.
How accurate is the test?
This test uses enzyme-linked immunosorbent assay (ELISA) technology, which is highly specific for detecting sIgA in saliva or stool samples. The test has a specificity of 98% and a sensitivity of 96%. TrueHealthLabs.com partners with CLIA-certified and CAP-certified laboratories to uphold rigorous testing standards for dependable results.
Important Notes
READ: These tests are available for European countries only.
Medical Review Board
Reviewed by Jeff Donohue M.D. from Body Logic and Brady Hurst DC, CCCN. Written by True Health Lab’s team of editorial health contributors.
Disclaimer: This information is for educational purposes only and not intended as medical advice. Consult your healthcare provider for personalized guidance.
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