What is the Natural Killer Cell and Activated T-Cell Profile?
The Natural Killer Cell and Activated T-Cell Profile is a blood test that measures the activity and presence of natural killer cells (NK cells) and activated T-cells, specifically focusing on CD25 markers. NK cells are a type of lymphocyte that plays a critical role in the body’s immune response by targeting virus-infected cells and tumors. Activated T-cells, including regulatory T-cells, help manage and direct the immune response, ensuring it targets the right pathogens while avoiding damage to healthy tissue.
Why is this Test Important?
Understanding its activity is vital for diagnosing and monitoring various immune-related conditions, including autoimmune diseases, chronic infections, and cancers. This profile may help in assessing immune function, guiding treatment decisions, and monitoring the effectiveness of therapies. In functional medicine, this test may provide insights into chronic fatigue syndrome, chronic infections, and other conditions linked to immune dysregulation. Talk to your primary healthcare provider if you are also experiencing the said symptoms.
Why Consider Ordering this Test?
If you have symptoms of immune dysfunction, such as chronic fatigue, frequent infections, or unexplained inflammation, this test may provide valuable information. Talk to your primary healthcare provider if you are also experiencing the said symptoms. It may also help you and your healthcare provider understand your immune system’s current state and guide appropriate interventions to restore balance and improve overall health. Early detection and monitoring are key to managing and treating immune-related conditions effectively.
Labs Included in Your Order
| Test Name | Reference Ranges | Low and High Levels of Biomarkers |
|---|---|---|
| Natural Killer Cells (CD16+/CD56+) |
|
High: High levels of NK cells may indicate an acute viral infection or a response to malignancy.
Low: Low levels of NK cells may suggest immune suppression or chronic viral infections. |
| Activated T-Cells (CD25+) |
|
High: High levels of activated T-cells may indicate an ongoing immune response, such as an infection or autoimmune condition.
Low: Low levels of activated T-cells may indicate immune deficiency or a regulatory imbalance. |
Natural Killer Cell and Activated T-Cell Profile FAQ
What is the Natural Killer Cell and Activated T-Cell Profile for?
This profile measures the activity and presence of NK cells and activated T-cells to assess immune function and diagnose or monitor immune-related conditions.
What do low and high levels mean?
High levels may indicate acute infections, malignancies, or autoimmune responses. Low levels may suggest immune suppression, chronic infections, or regulatory imbalances. Talk to your primary healthcare provider if you are also experiencing these symptoms.
What are the signs and symptoms of immune dysfunction?
Signs of immune dysfunction include chronic fatigue, frequent infections, unexplained inflammation, and poor wound healing. Talk to your primary healthcare provider if you are also experiencing the said symptoms.
How often should I retest?
Retesting frequency depends on your healthcare provider’s recommendations, typically based on your symptoms and treatment plan.
How accurate is the test?
This test is highly accurate and reliable, using standardized methods to measure NK cell and activated T-cell levels.
Are test results private and confidential?
Receive test results securely on TrueHealthLabs.com under ‘My Account.’ It’s critical that you share them with your physician. Results may be disclosed to health authorities only if legally mandated, e.g., for STDs or COVID-19. Review our privacy policy for more details.
To learn more, see our comprehensive guide to the Natural Killer Cell and Activated T-Cell Profile.
Medical Review Board
Reviewed by our medical review board consisting of Jeff Donohue M.D. from Body Logic and Brady Hurst DC, CCCN. Written by True Health Labs team of editorial health contributors.
Disclaimer: This information is for educational purposes only and not intended as medical advice. Consult your healthcare provider for personalized guidance.
