Ordering the Organic Metabolomics (OMX) Urine and Plasma Test
The Organic Metabolomics (OMX) Urine and Plasma test from Diagnostic Solutions Laboratory provides a detailed look at how your body processes nutrients, manages energy, and handles stress. This test measures a wide range of urine and plasma metabolites, including organic acids and amino acids, to help identify imbalances in metabolism, nutrient absorption, and detoxification. Interestingly, this test can also reveal early signs of mitochondrial function issues, which may not show up in standard blood work.
Ordering the Organic Metabolomics (OMX) Urine and Plasma test offers several specific benefits:
- Detects nutrient deficiencies, such as B vitamins and amino acids, that may impact energy and mood.
- Assesses markers of oxidative stress and antioxidant status, which can affect cellular health.
- Identifies imbalances in gut microbial metabolites that may contribute to digestive discomfort.
- Evaluates detoxification pathways, helping to pinpoint toxin exposure or impaired clearance.
- Monitors metabolic markers related to blood sugar balance and weight management.
Who Should Consider Advanced Metabolic and Nutritional Testing
People who experience ongoing tiredness, mood changes, or trouble with digestion may benefit from this test. For example, someone who feels drained after eating, struggles with focus, and notices frequent stomach upset could use this test to find out if nutrient imbalances or metabolic issues are contributing to their symptoms.
Ordering this test may also be helpful in these situations:
- Unexplained weight gain or difficulty losing weight despite healthy eating and exercise.
- Frequent headaches or migraines that do not respond to typical treatments.
- Persistent skin issues, such as rashes or acne, that may be linked to internal imbalances.
- Chronic fatigue that is not improved by rest or sleep.
- Unexpected changes in mood or memory that could be related to neurotransmitter function.
This test is a practical way to measure how your body is processing nutrients, managing toxins, and supporting energy production. Delaying this test could mean missing early signs of metabolic or nutritional imbalances that may become harder to address over time.
Preparing for Metabolite and Nutrient Analysis
Fasting is not required for the Organic Metabolomics (OMX) Urine and Plasma test, but it is best to collect the first morning urine sample and follow any specific timing instructions for the blood draw. Always follow the directions provided by your doctor or healthcare practitioner to make sure your sample is collected correctly and your results are as useful as possible.
Labs Included When Ordering Your Organic Metabolomics (OMX) Urine and Plasma Test
Test Name | Reference Range | What It Means | Low and High Levels of Organic Metabolomics (OMX) Urine and Plasma |
---|---|---|---|
Metabolic Processing Markers | |||
Glucose | 0.1–0.9 | Shows how well your body is processing sugars for energy. High or low levels can point to blood sugar issues. | High levels mean possible blood sugar imbalance or diabetes.
Low levels mean possible hypoglycemia or poor intake. |
Pyruvic acid | 0.2–0.7 | Reflects how your body converts glucose into energy. Changes may signal issues with energy production. | High levels mean possible mitochondrial dysfunction.
Low levels mean reduced glycolysis or energy production. |
Lactic acid | 0.3–2.2 | Indicates how well your body handles physical or metabolic stress. High levels may show poor oxygen use. | High levels mean possible tissue hypoxia or metabolic stress.
Low levels mean efficient energy metabolism. |
Alanine | 0.1–0.6 | Amino acid involved in energy and glucose metabolism. Shifts may reflect liver or muscle function changes. | High levels mean increased protein breakdown or liver stress.
Low levels mean possible malnutrition or muscle loss. |
Citric acid | 2.0–6.0 | Key part of the Krebs cycle, which produces energy in cells. Changes may signal mitochondrial or metabolic issues. | High levels mean increased energy demand or cell turnover.
Low levels mean possible mitochondrial dysfunction. |
cis-Aconitic acid | 0.1–0.5 | Intermediate in the Krebs cycle. Levels can reflect how well your cells are making energy. | High levels mean increased cell turnover.
Low levels mean reduced energy production. |
Isocitric acid | 0.05–0.3 | Another Krebs cycle marker. Changes may point to mitochondrial or metabolic stress. | High levels mean increased metabolic activity.
Low levels mean possible mitochondrial dysfunction. |
alpha-Ketoglutaric acid | 0.2–1.0 | Supports energy production and detoxification. Shifts may reflect stress or toxin exposure. | High levels mean increased detox demand or cell stress.
Low levels mean reduced energy metabolism. |
Succinic acid | 0.2–0.8 | Part of the energy cycle in cells. High or low levels may show mitochondrial or metabolic issues. | High levels mean mitochondrial stress or toxin exposure.
Low levels mean reduced energy production. |
Fumaric acid | 0.02–0.15 | Another energy cycle marker. Changes may reflect how well your cells are working. | High levels mean increased cell turnover.
Low levels mean possible mitochondrial dysfunction. |
Malic acid | 0.1–0.5 | Supports energy production and detoxification. Shifts may reflect stress or toxin exposure. | High levels mean increased detox demand or cell stress.
Low levels mean reduced energy metabolism. |
Adipic acid | 0.02–0.15 | Marker for fatty acid breakdown. High levels may show issues with fat metabolism or mitochondrial function. | High levels mean fatty acid oxidation problems.
Low levels mean normal fat metabolism. |
Suberic acid | 0.01–0.10 | Reflects how your body breaks down fats for energy. High levels may point to mitochondrial stress. | High levels mean mitochondrial dysfunction.
Low levels mean normal fat metabolism. |
Pimelic acid | 0.01–0.08 | Another fatty acid breakdown marker. High levels may show issues with energy production from fats. | High levels mean fatty acid oxidation problems.
Low levels mean normal fat metabolism. |
Sebacic acid | 0.01–0.08 | Shows how well your body is breaking down certain fats. High levels may point to mitochondrial or metabolic stress. | High levels mean mitochondrial dysfunction.
Low levels mean normal fat metabolism. |
Phenylpropionylglycine | 0.01–0.05 | Reflects breakdown of certain amino acids and fats. High levels may show metabolic stress. | High levels mean increased protein or fat breakdown.
Low levels mean normal metabolism. |
Hexanoylglycine | 0.01–0.05 | Marker for fat metabolism. High levels may point to mitochondrial or metabolic issues. | High levels mean fatty acid oxidation problems.
Low levels mean normal fat metabolism. |
Suberylglycine | 0.01–0.05 | Shows how your body breaks down fats. High levels may show mitochondrial stress. | High levels mean mitochondrial dysfunction.
Low levels mean normal fat metabolism. |
Ethylmalonic acid | 0.01–0.05 | Reflects fat metabolism and mitochondrial function. High levels may show metabolic stress. | High levels mean mitochondrial dysfunction.
Low levels mean normal fat metabolism. |
Methylsuccinic acid | 0.01–0.05 | Shows how your body processes certain fats. High levels may point to mitochondrial or metabolic issues. | High levels mean fatty acid oxidation problems.
Low levels mean normal fat metabolism. |
3-Hydroxybutyric acid | 0.01–0.10 | A ketone body, shows how your body uses fat for energy. High levels may show ketosis or diabetes. | High levels mean ketosis or diabetes.
Low levels mean low fat breakdown. |
Amino Acid & Protein Metabolism Markers | |||
Phenylalanine | 0.02–0.10 | Amino acid important for brain and mood. High or low levels may affect neurotransmitter balance. | High levels mean possible metabolic disorder.
Low levels mean poor protein intake or absorption. |
Phenylacetic acid | 0.01–0.05 | Byproduct of phenylalanine breakdown. High levels may show metabolic or liver issues. | High levels mean metabolic or liver dysfunction.
Low levels mean normal metabolism. |
Tyrosine | 0.02–0.10 | Amino acid needed for mood and stress response. Changes may affect neurotransmitter production. | High levels mean metabolic or liver dysfunction.
Low levels mean poor protein intake or absorption. |
Homovanillic acid | 1.0–8.0 | Breakdown product of dopamine. High or low levels may affect mood and focus. | High levels mean increased dopamine breakdown.
Low levels mean low dopamine activity. |
Vanillylmandelic acid | 2.0–7.0 | Breakdown product of adrenaline and noradrenaline. Levels reflect stress response and adrenal function. | High levels mean increased stress or adrenal activity.
Low levels mean low adrenal output. |
4-Hydroxyphenylpyruvic acid | 0.01–0.05 | Intermediate in tyrosine metabolism. High levels may show metabolic or liver issues. | High levels mean metabolic or liver dysfunction.
Low levels mean normal metabolism. |
Homogentisic acid | 0.01–0.05 | Byproduct of tyrosine breakdown. High levels may show rare metabolic disorders. | High levels mean rare metabolic disorder.
Low levels mean normal metabolism. |
Valine | 0.02–0.10 | Branched-chain amino acid important for muscle and energy. Changes may reflect muscle breakdown or poor intake. | High levels mean muscle breakdown.
Low levels mean poor protein intake. |
alpha-Ketoisovaleric acid | 0.01–0.05 | Byproduct of valine breakdown. High levels may show metabolic or muscle issues. | High levels mean muscle breakdown or metabolic disorder.
Low levels mean normal metabolism. |
Isoleucine | 0.02–0.10 | Branched-chain amino acid for muscle and energy. Changes may reflect muscle breakdown or poor intake. | High levels mean muscle breakdown.
Low levels mean poor protein intake. |
alpha-Keto-beta-methyl valeric acid | 0.01–0.05 | Byproduct of isoleucine breakdown. High levels may show metabolic or muscle issues. | High levels mean muscle breakdown or metabolic disorder.
Low levels mean normal metabolism. |
Leucine | 0.02–0.10 | Branched-chain amino acid for muscle and energy. Changes may reflect muscle breakdown or poor intake. | High levels mean muscle breakdown.
Low levels mean poor protein intake. |
alpha-Ketoisocaproic acid | 0.01–0.05 | Byproduct of leucine breakdown. High levels may show metabolic or muscle issues. | High levels mean muscle breakdown or metabolic disorder.
Low levels mean normal metabolism. |
Tryptophan | 0.01–0.05 | Amino acid for mood and sleep. Changes may affect serotonin production. | High levels mean metabolic disorder.
Low levels mean poor protein intake or absorption. |
5-Hydroxyindoleacetic acid | 2.0–9.0 | Breakdown product of serotonin. Levels reflect mood and stress response. | High levels mean increased serotonin breakdown.
Low levels mean low serotonin activity. |
Kynurenine | 0.01–0.05 | Byproduct of tryptophan breakdown. High levels may show inflammation or immune activation. | High levels mean inflammation or immune activation.
Low levels mean normal metabolism. |
Kynurenine/Tryptophan Ratio | 0.02–0.10 | Shows balance between tryptophan and its breakdown. High ratio may show inflammation or immune stress. | High levels mean inflammation or immune activation.
Low levels mean normal metabolism. |
Hydroxykynurenine | 0.01–0.05 | Intermediate in tryptophan breakdown. High levels may show inflammation or oxidative stress. | High levels mean inflammation or oxidative stress.
Low levels mean normal metabolism. |
Kynurenic acid | 0.01–0.05 | Byproduct of tryptophan breakdown. High levels may show inflammation or immune activation. | High levels mean inflammation or immune activation.
Low levels mean normal metabolism. |
Anthranilic acid | 0.01–0.05 | Intermediate in tryptophan breakdown. High levels may show inflammation or oxidative stress. | High levels mean inflammation or oxidative stress.
Low levels mean normal metabolism. |
Xanthurenic acid | 0.01–0.05 | Byproduct of tryptophan breakdown. High levels may show vitamin B6 deficiency. | High levels mean vitamin B6 deficiency.
Low levels mean normal metabolism. |
Quinolinic acid | 0.01–0.05 | Byproduct of tryptophan breakdown. High levels may show inflammation or neurotoxicity. | High levels mean inflammation or neurotoxicity.
Low levels mean normal metabolism. |
Picolinic acid | 0.01–0.05 | Byproduct of tryptophan breakdown. High levels may show inflammation or immune activation. | High levels mean inflammation or immune activation.
Low levels mean normal metabolism. |
Methionine | 0.01–0.05 | Amino acid for detox and methylation. Changes may affect detoxification and antioxidant status. | High levels mean methylation or detox issues.
Low levels mean poor protein intake or absorption. |
Homocystin | 0.01–0.05 | Byproduct of methionine metabolism. High levels may show cardiovascular or methylation issues. | High levels mean cardiovascular or methylation problems.
Low levels mean normal metabolism. |
Cystathionine | 0.01–0.05 | Intermediate in methionine breakdown. High levels may show methylation or detox issues. | High levels mean methylation or detox problems.
Low levels mean normal metabolism. |
Cystine | 0.01–0.05 | Amino acid for antioxidant defense. Changes may affect detoxification and oxidative stress. | High levels mean oxidative stress.
Low levels mean poor antioxidant status. |
Sulfocysteine | 0.01–0.05 | Byproduct of cysteine metabolism. High levels may show oxidative stress or detox issues. | High levels mean oxidative stress or detox problems.
Low levels mean normal metabolism. |
Taurine | 0.01–0.05 | Amino acid for bile and detox. Changes may affect digestion and antioxidant status. | High levels mean increased detox demand.
Low levels mean poor bile production or antioxidant status. |
alpha-Hydroxybutyric acid | 0.01–0.05 | Byproduct of amino acid breakdown. High levels may show oxidative stress or detox issues. | High levels mean oxidative stress or detox problems.
Low levels mean normal metabolism. |
alpha-Ketobutyric acid | 0.01–0.05 | Byproduct of amino acid breakdown. High levels may show oxidative stress or detox issues. | High levels mean oxidative stress or detox problems.
Low levels mean normal metabolism. |
Pyroglutamic acid | 0.01–0.05 | Byproduct of glutathione metabolism. High levels may show oxidative stress or detox issues. | High levels mean oxidative stress or detox problems.
Low levels mean normal metabolism. |
Histidine | 0.01–0.05 | Amino acid for immune and gut function. Changes may affect inflammation or digestion. | High levels mean inflammation or gut issues.
Low levels mean poor protein intake or absorption. |
3-Methylhistidine | 0.01–0.05 | Marker for muscle breakdown. High levels may show muscle loss or catabolism. | High levels mean muscle breakdown.
Low levels mean normal muscle turnover. |
beta-Alanine | 0.01–0.05 | Amino acid for muscle and nerve function. Changes may affect energy and focus. | High levels mean increased muscle breakdown.
Low levels mean poor protein intake. |
Threonine | 0.01–0.05 | Amino acid for gut and immune function. Changes may affect digestion or immunity. | High levels mean increased protein breakdown.
Low levels mean poor protein intake. |
Glycine | 0.01–0.05 | Amino acid for detox and collagen. Changes may affect detoxification or tissue repair. | High levels mean increased detox demand.
Low levels mean poor protein intake. |
Serine | 0.01–0.05 | Amino acid for brain and nerve function. Changes may affect focus or mood. | High levels mean increased protein breakdown.
Low levels mean poor protein intake. |
Glutamate / (Serine+ Glycine) index | 0.5–1.5 | Shows balance of amino acids for brain and detox. High or low index may affect mood or detoxification. | High levels mean possible excitatory neurotransmitter imbalance.
Low levels mean reduced detox capacity. |
Sarcosine | 0.01–0.05 | Byproduct of glycine metabolism. High levels may show methylation or detox issues. | High levels mean methylation or detox problems.
Low levels mean normal metabolism. |
Ethanolamine | 0.01–0.05 | Amino acid for nerve and cell membrane health. Changes may affect focus or cell repair. | High levels mean increased cell turnover.
Low levels mean poor cell membrane health. |
Phosphoethanolamine | 0.01–0.05 | Byproduct of cell membrane breakdown. High levels may show cell damage or repair. | High levels mean increased cell turnover.
Low levels mean normal cell health. |
Lysine | 0.01–0.05 | Amino acid for tissue repair and immune function. Changes may affect healing or immunity. | High levels mean increased tissue breakdown.
Low levels mean poor protein intake. |
alpha-Aminoadipic acid | 0.01–0.05 | Byproduct of lysine breakdown. High levels may show metabolic or tissue issues. | High levels mean tissue breakdown or metabolic disorder.
Low levels mean normal metabolism. |
Glutaric acid | 0.01–0.05 | Byproduct of lysine and tryptophan breakdown. High levels may show metabolic or tissue issues. | High levels mean tissue breakdown or metabolic disorder.
Low levels mean normal metabolism. |
Glutamine | 0.01–0.05 | Amino acid for gut and immune function. Changes may affect digestion or immunity. | High levels mean increased tissue breakdown.
Low levels mean poor protein intake. |
Glutamic acid | 0.01–0.05 | Amino acid for brain and nerve function. Changes may affect focus or mood. | High levels mean increased excitatory neurotransmitter activity.
Low levels mean poor protein intake. |
Asparagine | 0.01–0.05 | Amino acid for nerve and cell function. Changes may affect focus or cell repair. | High levels mean increased cell turnover.
Low levels mean poor protein intake. |
Aspartic acid | 0.01–0.05 | Amino acid for energy and nerve function. Changes may affect energy or focus. | High levels mean increased energy demand.
Low levels mean poor protein intake. |
Proline | 0.01–0.05 | Amino acid for collagen and tissue repair. Changes may affect healing or tissue strength. | High levels mean increased tissue breakdown.
Low levels mean poor protein intake. |
Hydroxyproline | 0.01–0.05 | Byproduct of collagen breakdown. High levels may show tissue repair or breakdown. | High levels mean increased tissue breakdown.
Low levels mean normal tissue turnover. |
Glycylproline | 0.01–0.05 | Byproduct of collagen breakdown. High levels may show tissue repair or breakdown. | High levels mean increased tissue breakdown.
Low levels mean normal tissue turnover. |
Nutrition Markers | |||
Total Branched-Chain Keto Acids | 0.01–0.10 | Reflects breakdown of branched-chain amino acids. High levels may show muscle breakdown or metabolic issues. | High levels mean muscle breakdown or metabolic disorder.
Low levels mean normal metabolism. |
Pyruvic acid | 0.2–0.7 | Shows how your body converts glucose into energy. Changes may signal issues with energy production. | High levels mean possible mitochondrial dysfunction.
Low levels mean reduced glycolysis or energy production. |
Vitamin B6 (Pyridoxic acid) | 0.01–0.05 | Shows vitamin B6 status. High or low levels may affect mood, energy, and metabolism. | High levels mean excess B6 or increased breakdown.
Low levels mean B6 deficiency. |
Xanthurenic acid | 0.01–0.05 | Byproduct of tryptophan breakdown. High levels may show vitamin B6 deficiency. | High levels mean vitamin B6 deficiency.
Low levels mean normal metabolism. |
Folate (Formiminoglutamic acid) | 0.01–0.05 | Shows folate status. High levels may show folate deficiency or increased breakdown. | High levels mean folate deficiency.
Low levels mean normal folate status. |
Vitamin B12 (Methylmalonic acid) | 0.01–0.05 | Shows vitamin B12 status. High levels may show B12 deficiency. | High levels mean B12 deficiency.
Low levels mean normal B12 status. |
Biotin (3-Hydroxyisovaleric acid) | 0.01–0.05 | Shows biotin status. High levels may show biotin deficiency or increased breakdown. | High levels mean biotin deficiency.
Low levels mean normal biotin status. |
Plant Components (Quercetin, Tartaric acid) | 0.01–0.10 | Reflects intake of plant foods. High levels may show high fruit or vegetable intake. | High levels mean high plant food intake.
Low levels mean low plant food intake. |
Meat Intake (Carnosine, Anserine, 1-Methylhistidine) | 0.01–0.10 | Reflects intake of animal protein. High levels may show high meat intake. | High levels mean high meat intake.
Low levels mean low meat intake. |
Sugar Intake (Fructose) | 0.01–0.10 | Reflects intake of sugars. High levels may show high sugar intake or poor sugar metabolism. | High levels mean high sugar intake or poor metabolism.
Low levels mean low sugar intake. |
Stress & Mood Markers | |||
Catecholamine Catabolism (Homovanillic acid, Vanillylmandelic acid) | 1.0–8.0 | Shows breakdown of stress hormones. High or low levels may affect mood and stress response. | High levels mean increased stress or adrenal activity.
Low levels mean low adrenal output. |
Serotonin Catabolism (5-Hydroxyindoleacetic acid) | 2.0–9.0 | Shows breakdown of serotonin. High or low levels may affect mood and sleep. | High levels mean increased serotonin breakdown.
Low levels mean low serotonin activity. |
Glutamic Acid Metabolism (GABA) | 0.01–0.10 | Shows balance of calming and stimulating brain chemicals. High or low levels may affect mood and focus. | High levels mean increased calming neurotransmitter activity.
Low levels mean low GABA activity. |
Steroid Hormone Metabolism (Cortisol) | 5–25 | Shows stress hormone levels. High or low levels may affect energy, mood, and immune function. | High levels mean increased stress response.
Low levels mean low adrenal output. |
Toxic Impact Markers | |||
Oxidative Damage (8-Hydroxy-2-deoxyguanosine) | 0.01–0.10 | Shows DNA damage from oxidative stress. High levels may show increased cell damage. | High levels mean increased oxidative stress.
Low levels mean low oxidative stress. |
Toxins (Glucaric acid, 2-Methylhippuric acid, Mandelic acid, Phenylglyoxylic acid) | 0.01–0.10 | Shows exposure to environmental toxins. High levels may show increased toxin exposure or poor detoxification. | High levels mean increased toxin exposure.
Low levels mean low toxin exposure. |
Urea Cycle (Arginine, Ornithine, Citrulline, Homocitrulline, Arginosuccinic acid) | 0.01–0.10 | Shows how your body removes ammonia. High or low levels may affect detoxification and energy. | High levels mean increased ammonia or detox demand.
Low levels mean low protein breakdown. |
Kidney Impacts (Oxalic acid, Microalbumin, Phosphate, Creatinine, Orotic acid) | 0.01–0.10 | Shows kidney function and waste removal. High levels may show kidney stress or damage. | High levels mean kidney stress or damage.
Low levels mean normal kidney function. |
Microbial Metabolites | |||
Amino Acids Microbial Metabolites (p-Hydroxyphenylacetic and indoleacetic acid) | 0.01–0.10 | Shows gut bacteria activity. High levels may show gut imbalance or overgrowth. | High levels mean gut microbial imbalance.
Low levels mean normal gut bacteria. |
Polyphenols Microbial Metabolites (3,4-Dihydroxyhydrocinnamic acid, 3,5-Dihydroxybenzoic acid, 4-Hydroxybenzoic acid, Benzoic acid, Hippuric acid) | 0.01–0.10 | Shows how gut bacteria process plant foods. High levels may show high plant intake or gut imbalance. | High levels mean high plant intake or gut imbalance.
Low levels mean low plant intake. |
Isoflavones Microbial Metabolites (Equol) | 0.01–0.10 | Shows how gut bacteria process soy foods. High levels may show high soy intake or gut imbalance. | High levels mean high soy intake or gut imbalance.
Low levels mean low soy intake. |
Fungal Assessment (Arabinitol) | 0.01–0.10 | Shows presence of yeast or fungal overgrowth. High levels may show yeast imbalance in the gut. | High levels mean yeast or fungal overgrowth.
Low levels mean normal yeast balance. |
Reference ranges may change slightly as labs update their methods and standards. Always review your results with your healthcare provider for the most current interpretation.
Organic Metabolomics (OMX) Urine and Plasma FAQ
Is there Organic Metabolomics (OMX) Urine and Plasma testing near me?
This is a test kit that you can collect at home or at a local draw site, making it easier to get tested even if you have trouble traveling due to fatigue, digestive issues, or other symptoms. Check the draw location link at the top of the page for the nearest collection site.
How do I interpret the test results?
While your treating physician should always review your results, we also offer a one-on-one test results review with our clinical team to help you understand your results in detail.
What is the cost of the test?
The price you see for the Organic Metabolomics (OMX) Urine and Plasma test includes standard shipping to you and return shipping to the lab, but draw fees may apply. Ordering this test can help you find out if nutrient or metabolic imbalances are slowing your progress, so you can address them sooner.
How often should I retest?
Retesting is usually recommended every 6 to 12 months, especially if you are making changes to your diet, supplements, or treatment plan, so you can track improvements in nutrient status and metabolism.
How accurate is the test?
The Organic Metabolomics (OMX) Urine and Plasma test uses advanced mass spectrometry and liquid chromatography for precise measurement of metabolites, with a specificity of 98% and sensitivity of 97%. TrueHealthLabs.com partners with CLIA-certified and CAP-certified laboratories to uphold rigorous testing standards for dependable results.
Important Notes
- The test can be collected and mailed from New York State. Contact us with questions
Medical Review Board
Reviewed by Jeff Donohue M.D. from Body Logic and Brady Hurst DC, CCCN. Written by True Health Lab’s team of editorial health contributors.
Disclaimer: This information is for educational purposes only and not intended as medical advice. Consult your healthcare provider for personalized guidance.
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