Ordering the MTHFR Genetic Test | Spectracell
The MTHFR Genetic Test from Spectracell helps identify specific changes in the MTHFR gene that can affect how the body processes folate and vitamin B12. These gene changes may influence homocysteine levels, which are linked to blood clots, heart disease, and other health concerns. Interestingly, some people with MTHFR gene changes may not show any symptoms but could still have higher risks for certain conditions, such as migraines or pregnancy complications.
Ordering this test can provide clear answers about your genetic makeup and how it may impact your body’s ability to use folate and vitamin B12. When you order the MTHFR Genetic Test, you can expect:
- Detection of two common MTHFR gene changes: C677T and A1298C
- Personalized information about your risk for high homocysteine levels
- Guidance for targeted nutrition and supplement choices
- Support for understanding possible links to chronic pain, fatigue, or mood changes
- Information to help with family planning or prenatal care decisions
Who Should Consider Genetic Methylation Testing
People who have a family history of heart disease, unexplained fatigue, or frequent migraines may benefit from this test. For example, someone who has experienced several miscarriages and is searching for answers may find this test helpful in uncovering a possible genetic cause.
Ordering this test may also be useful in these situations:
- Struggling with low vitamin B12 or folate levels despite supplements
- Experiencing chronic pain or neuropathy without a clear reason
- Having a personal or family history of blood clots or stroke
- Dealing with mood changes, anxiety, or depression that do not improve with standard treatments
- Discovering unexplained high homocysteine levels during routine blood work, which can be linked to gene changes
This test can help pinpoint if your body has trouble processing folate or vitamin B12, which may affect your risk for blood clots, heart disease, or pregnancy complications. Delaying this test could mean missing the chance to make simple changes that may lower your risk for these conditions.
Preparing for DNA Mutation Analysis
No fasting is needed before taking this test, and you can eat and drink as usual. Always follow any instructions your doctor or healthcare provider gives you to make sure your sample is collected correctly and your results are as helpful as possible.
Labs Included When Ordering Your MTHFR Genetic Test | Spectracell
| Test Name | Reference Range | What This Marker Means | Low and High Levels of MTHFR Genetic Test | Spectracell |
|---|---|---|---|
| C677T | Normal: CC Heterozygous: CT Homozygous: TT |
C677T is a common change in the MTHFR gene that can reduce the enzyme’s activity. This may lead to higher homocysteine levels and affect folate metabolism. |
High levels mean having one or two T copies (CT or TT) may increase the risk for blood clots, heart disease, or pregnancy problems.
Low levels mean having two C copies (CC) is linked to typical enzyme activity and lower risk for related conditions. |
| A1298C | Normal: AA Heterozygous: AC Homozygous: CC |
A1298C is another common change in the MTHFR gene that can lower enzyme function, especially when combined with C677T. This may impact detoxification and neurotransmitter production. |
High levels mean having one or two C copies (AC or CC) may increase the chance of mood changes, chronic pain, or trouble with detoxification.
Low levels mean having two A copies (AA) is linked to typical enzyme function and lower risk for related issues. |
Reference ranges may change slightly as labs update their standards and testing methods.
MTHFR Genetic Test | Spectracell FAQ
Is there MTHFR Genetic Test | Spectracell testing near me?
This test kit can be collected at a local draw site, which you can find using the draw location link at the top of the page. For people managing unexplained fatigue or recurring migraines, having a nearby collection site makes it easier to get tested quickly and start finding answers.
How do I interpret the test results?
While your treating physician should review your results, we also offer a one-on-one test results review with our clinical team to help you understand what your results mean and what steps you can take next.
What is the cost of the test?
The price listed for this test includes standard shipping to you and return shipping to the lab, though draw fees may apply at the collection site. Ordering this test can help you address unexplained symptoms like chronic pain or fatigue sooner, so you can work toward feeling better faster.
How often should I retest?
Retesting is usually only needed if your symptoms change, you start new supplements, or your doctor recommends it based on new health concerns. Checking again after making changes can show if your homocysteine levels or related symptoms have improved.
How accurate is the test?
This test uses polymerase chain reaction (PCR) to detect MTHFR gene changes, with a specificity of 99.9% and a sensitivity of 99.8%. TrueHealthLabs.com partners with CLIA-certified and CAP-certified laboratories to uphold rigorous testing standards for dependable results.
Important Notes
None.
Medical Review Board
Reviewed by Jeff Donohue M.D. from Body Logic and Brady Hurst DC, CCCN. Written by True Health Lab’s team of editorial health contributors.
Disclaimer: This information is for educational purposes only and not intended as medical advice. Consult your healthcare provider for personalized guidance.
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