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Lyme Multiplex PCR Urine Test | Igenex


  • Fasting: No
  • Specimen: Urine (Draw Location)
  • Processed by Igenex
  • Turnaround Time: 7-10 Business Days
  • Available in all states
  • HSA and FSA Approved!

$429.00 USD $615.00

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Ordering the Lyme Multiplex PCR Urine Test | Igenex

Ordering the Lyme Multiplex PCR Urine Test from Igenex helps detect Borrelia burgdorferi, the bacteria linked to Lyme disease, by identifying its DNA in urine samples. This test is especially useful for people who have symptoms that may not show up on standard blood tests. Interestingly, urine-based PCR testing can sometimes detect Lyme bacteria even when blood antibody levels are too low to be picked up by other tests.

When ordering this test, you can expect:

  • Direct detection of Borrelia burgdorferi DNA, not just antibodies
  • Non-invasive urine sample collection
  • Useful for early and late-stage Lyme disease detection
  • Helpful for people with ongoing symptoms after a tick bite
  • Can be mailed and collected in New York, offering more flexibility

Who Should Consider Lyme Disease DNA Testing

People who have had a tick bite and now experience joint pain, fatigue, or memory problems may benefit from this test. For example, someone who enjoys hiking and later develops unexplained muscle aches and brain fog might want to check for Lyme disease using this method.

Ordering this test may also be helpful in these situations:

  • After a tick bite with a rash that does not look like a bullseye
  • When symptoms like facial paralysis or heart palpitations appear weeks after outdoor activities
  • If previous Lyme tests were negative but symptoms continue
  • For people with neurological symptoms such as tingling or numbness
  • When unexplained hearing issues develop after time spent in wooded areas

This test is recommended for those who want to confirm the presence of Lyme bacteria, especially if symptoms are ongoing or unclear. Delaying this test could mean missing the best window for early detection, which may make treatment more complicated later.

Preparing for Your Lyme Bacteria DNA Urine Analysis

Fasting is not required before providing a urine sample for this test, so you can eat and drink as usual. Always follow any specific instructions your doctor or healthcare provider gives you to make sure your sample is collected correctly and the results are as useful as possible.

Labs Included When Ordering Your Lyme Multiplex PCR Urine Test | Igenex

Test Name Reference Range Significance Low and High Levels of Lyme Multiplex PCR Urine Test
Lyme Multiplex PCR (urine samples) Negative This test looks for Borrelia burgdorferi DNA in urine, which helps confirm if the Lyme bacteria is present in the body. It is especially useful for people with symptoms but negative antibody tests. High levels mean Borrelia burgdorferi DNA was detected, suggesting an active or recent infection.

Low levels mean no Lyme bacteria DNA was found, making an active infection less likely.

Reference ranges may change slightly as labs update their testing methods and guidelines.


Lyme Multiplex PCR Urine Test FAQ

Is there Lyme Multiplex PCR Urine Test testing near me?

This is a test kit you can order and collect your urine sample locally, making it easier for people with symptoms like joint pain or fatigue to get tested without traveling far. Check the draw location link at the top of the page for more details.

How do I interpret the test results?

While your treating physician should review your results, you can also use our one-on-one test results review service with our clinical team for extra support.

What is the cost of the test?

The price you see includes standard shipping to you and back to the lab, but draw fees may apply. Ordering this test can help you find out if Lyme bacteria is present, which can help you and your doctor start treatment sooner.

How often should I retest?

Retesting is usually recommended if symptoms return or if you are monitoring treatment progress, often every few months. Reordering helps track changes in Lyme bacteria levels and supports better treatment decisions.

How accurate is the test?

This test uses polymerase chain reaction (PCR) to detect Borrelia burgdorferi DNA, with a specificity of 99% and a sensitivity of 85%. TrueHealthLabs.com partners with CLIA-certified and CAP-certified laboratories to uphold rigorous testing standards for dependable results.

Important Notes

  • This test can be mailed and collected in New York.

Medical Review Board

Reviewed by Jeff Donohue M.D. from Body Logic and Brady Hurst DC, CCCN. Written by True Health Lab’s team of editorial health contributors.

Disclaimer: This information is for educational purposes only and not intended as medical advice. Consult your healthcare provider for personalized guidance.


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