Ordering the IgG and IgM Antibody for Human Monocytic Erhlichia (HME) Test
Testing for Human Monocytic Ehrlichia IgG and IgM antibodies helps identify if your body has been exposed to the bacteria that cause ehrlichiosis, a tick-borne illness. This test can help your healthcare provider determine if you have a current or past infection, which is important for guiding treatment and monitoring your recovery. Interestingly, some people may not show obvious symptoms, but still have detectable antibodies, which can help explain unexplained symptoms like fatigue or joint pain.
Ordering this test can provide:
- Clear evidence of recent or past exposure to Human Monocytic Ehrlichia bacteria
- Support for your healthcare provider in making a diagnosis when symptoms are unclear
- Information to help guide treatment decisions and monitor response to therapy
- Documentation for tracking changes in antibody levels over time
- Peace of mind if you have had a tick bite or live in an area where ehrlichiosis is common
Who Should Consider Antibody Testing for Tick-Borne Illnesses
People who have experienced unexplained fever, body aches, or a rash after spending time outdoors in wooded or grassy areas may benefit from this test. For example, someone who recently went hiking and later developed fatigue and joint pain might want to check for antibodies to help explain their symptoms.
Ordering this test may also be helpful in these situations:
- After a known tick bite, especially if symptoms develop within a few weeks
- When symptoms like headache, chills, or muscle pain persist without a clear cause
- If you live in or have traveled to areas where tick-borne diseases are common
- When other tests for infections have not explained ongoing symptoms
- For people with a history of autoimmune conditions, as antibody levels can sometimes overlap with tick-borne infections
Testing for these antibodies can help pinpoint the cause of symptoms like fever, fatigue, or joint pain, and guide your provider in choosing the right treatment. Delaying this test could mean missing the best window for early treatment, which may make symptoms last longer or become harder to manage.
Preparing for Tick-Borne Disease Antibody Testing
Fasting is not required for this test, so you can eat and drink as usual before your blood draw. Make sure to carefully follow any instructions your doctor or healthcare provider gives you to ensure your sample is collected correctly and processed without delay.
Labs Included When Ordering Your IgG and IgM Antibody for Human Monocytic Erhlichia (HME)
| Test Name | Reference Range | What the Biomarker Means | Low and High Levels of IgG and IgM Antibody for Human Monocytic Erhlichia (HME) |
|---|---|---|---|
| Human Monocytic Ehrlichia IgG Antibody | Negative: <1:64 Equivocal: 1:64 Positive: >1:64 |
This marker shows if your immune system has produced IgG antibodies to Human Monocytic Ehrlichia, which usually appear weeks after infection. IgG levels can help determine if you have had a past infection or a longer-lasting response. |
High levels mean your body has likely been exposed to the bacteria in the past or has a long-standing infection.
Low levels mean there is no evidence of past exposure or infection, or it may be too early for IgG to appear. |
| Human Monocytic Ehrlichia IgM Antibody | Negative: <1:20 Equivocal: 1:20 Positive: >1:20 |
This marker detects IgM antibodies, which are usually the first to appear after infection with Human Monocytic Ehrlichia. IgM levels can help identify a recent or current infection. |
High levels mean you may have a recent or active infection with Human Monocytic Ehrlichia.
Low levels mean there is no sign of a recent infection, or it may be too early for IgM to be detected. |
Reference ranges may change slightly as labs update their methods and guidelines.
IgG and IgM Antibody for Human Monocytic Erhlichia (HME) FAQ
Is there IgG and IgM Antibody for Human Monocytic Erhlichia (HME) testing near me?
This test is provided as a kit that you can use at a local draw site, making it easier to get tested quickly if you’re dealing with symptoms like fever or joint pain after a tick bite and need fast, accessible sample collection.
How do I interpret the test results?
While your treating physician should review your results, you can also use our one-on-one test results review service with our clinical team for a detailed explanation and next steps.
What is the cost of the test?
The price you see includes standard shipping to you and return shipping to the lab, though a draw fee may be charged at the collection site. Ordering this test can help you get answers sooner, especially if you’re experiencing symptoms that could be linked to tick-borne illness.
How often should I retest?
Retesting is usually recommended 2–4 weeks after the first test if symptoms continue or if your provider wants to track changes in antibody levels, which can help confirm a new infection or monitor your recovery.
How accurate is the test?
This test uses an indirect immunofluorescence assay (IFA) method, with a specificity of 98% and a sensitivity of 94% for detecting Human Monocytic Ehrlichia antibodies. TrueHealthLabs.com partners with CLIA-certified and CAP-certified laboratories to uphold rigorous testing standards for dependable results.
Important Notes
None.
Medical Review Board
Reviewed by Jeff Donohue M.D. from Body Logic and Brady Hurst DC, CCCN. Written by True Health Lab’s team of editorial health contributors.
Disclaimer: This information is for educational purposes only and not intended as medical advice. Consult your healthcare provider for personalized guidance.
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