Ordering the HLA-DQ2 and HLA-DQ8 Gene Test
Ordering the HLA-DQ2 and HLA-DQ8 Gene Test is important for those who suspect they might have celiac disease. This test helps identify genetic markers associated with the condition, providing valuable information for diagnosis and management. Interestingly, more than 95% of individuals with celiac disease test positive for either HLA-DQ2 or HLA-DQ8, making this test a key component in understanding your genetic predisposition.
Here are some specific benefits of the test:
- Identifies genetic markers linked to celiac disease.
- Helps in confirming a celiac disease diagnosis.
- Assists in determining if gluten can be reintroduced into the diet.
- Provides insight into family risk factors.
- Supports personalized dietary planning.
Who Should Consider Genetic Testing for Celiac Disease
Individuals experiencing persistent digestive discomfort or those with a family history of celiac disease may find this test beneficial. For example, a person who has been experiencing unexplained fatigue and digestive issues might consider this test to explore potential genetic links to their symptoms.
Other scenarios where this test might be considered include:
- Having a first-degree relative diagnosed with celiac disease.
- Experiencing symptoms that suggest gluten sensitivity.
- Being diagnosed with an autoimmune disorder.
- Having unexplained iron deficiency anemia.
- Being part of a population with a higher prevalence of celiac disease.
Consider ordering the test if any of these situations apply to you.
Preparing for Your Genetic Test
No fasting is required for the HLA-DQ2 and HLA-DQ8 Gene Test. If you are taking medications or supplements, it is important to follow any specific instructions provided by your healthcare provider.
Labs Included When Ordering Your HLA-DQ2 and HLA-DQ8 Gene Test
| Test Name | Reference Ranges | Significance | Low and High Levels of HLA-DQ2 and HLA-DQ8 |
|---|---|---|---|
| HLA-DQ2 Gene (alpha and beta subunits) | Positive or Negative | This gene is a marker for celiac disease susceptibility. Testing for HLA-DQ2 helps in assessing genetic risk. | High levels mean increased genetic risk for celiac disease.
Low levels mean reduced genetic risk for celiac disease. |
| HLA-DQ8 Gene (alpha and beta subunits) | Positive or Negative | Presence of this gene indicates a genetic predisposition to celiac disease. It is crucial for understanding potential gluten intolerance. | High levels mean increased genetic risk for celiac disease.
Low levels mean reduced genetic risk for celiac disease. |
Reference ranges can vary, so please check the Quest Diagnostics lab test directory for updated ranges.
HLA-DQ2 and HLA-DQ8 Gene Test FAQ
Is there HLA-DQ2 and HLA-DQ8 Gene Test testing near me?
You can find nearby draw locations with our patient service center locator, which also offers mobile phlebotomy options.
What is the cost of the test?
The cost of the HLA-DQ2 and HLA-DQ8 Gene Test can be found at the top of the page. Pricing includes draw fees when visiting patient service centers.
How often should I retest?
Retesting is generally not necessary unless there are significant changes in symptoms or family history. It is important to discuss any concerns with your healthcare provider.
How accurate is the test?
The HLA-DQ2 and HLA-DQ8 Gene Test uses advanced genetic analysis to identify specific markers associated with celiac disease. This method ensures high accuracy in detecting genetic predispositions. TrueHealthLabs.com only partners with CLIA-certified labs to ensure quality and reliability.
Medical Review Board
Reviewed by Jeff Donohue M.D. from Body Logic and Brady Hurst DC, CCCN. Written by True Health Lab’s team of editorial health contributors.
Disclaimer: This information is for educational purposes only and not intended as medical advice. Consult your healthcare provider for personalized guidance.
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