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Histone Antibody Test


  • Draw Locations
  • Turnaround Time: 2-4 Business Days on Average. Time may vary.
  • Not Available in: NY, NJ, MA, and RI
  • HSA and FSA Approved

$129.00 USD $327.84

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Ordering the Histone Antibody Test

Ordering the Histone Antibody Test can help identify autoimmune conditions by detecting antibodies against histones, which are proteins found in cell nuclei. Interestingly, this test can also provide insights into drug-induced lupus, a condition that mimics lupus symptoms due to certain medications.

When ordering this test, consider the following benefits:

  • Helps in diagnosing autoimmune disorders.
  • Assists in monitoring disease progression.
  • Supports treatment planning by identifying specific antibodies.
  • Provides clarity on unexplained symptoms.
  • Offers insights into drug-induced lupus.

Who Should Consider the Test

People experiencing persistent joint pain and fatigue, which are common symptoms of autoimmune disorders, might find this test beneficial. For example, someone who has been dealing with unexplained skin rashes and joint stiffness could gain valuable information from this test.

Consider ordering this test if you:

  • Have a family history of autoimmune diseases.
  • Experience chronic fatigue and joint pain.
  • Notice unusual skin rashes.
  • Have been exposed to medications known to induce lupus-like symptoms.
  • Are undergoing evaluation for systemic lupus erythematosus.

Ordering this test can help pinpoint the cause of your symptoms, leading to more targeted treatment. Delaying the test might result in prolonged uncertainty about your condition.

Preparing for the Test

Fasting for 10-12 hours is required before taking the Histone Antibody Test. It’s important to follow any instructions from your doctor or healthcare professional to ensure the test is conducted properly.

Labs Included When Ordering Your Histone Antibody Test

Test Name Reference Range Significance Low and High Levels of Histone Antibody Test
Histone Antibody Negative Histone antibodies are linked to autoimmune conditions, particularly lupus. They help in diagnosing and monitoring these diseases. High levels mean a possible autoimmune disorder, such as lupus.

Low levels mean less likelihood of an autoimmune condition.

Reference ranges may differ. Visit the Quest Diagnostics lab test directory for the latest values.


Histone Antibody Test FAQ

Is there Histone Antibody testing near me?

To find nearby locations for the Histone Antibody Test, use the patient service center locator, which includes mobile phlebotomy options. This is especially useful for those with limited mobility or who need quick access to testing due to ongoing symptoms.

What is the cost of the test?

The cost of the Histone Antibody Test includes all fees, such as sample collection at patient service centers. Ordering this test is worthwhile as it helps identify specific autoimmune conditions, aiding in effective treatment planning.

How often should I retest?

Retesting is generally recommended every 6 to 12 months, depending on your symptoms and treatment plan. Regular testing helps track disease progression and adjust treatments as needed.

How accurate is the test?

The Histone Antibody Test uses enzyme-linked immunosorbent assay (ELISA) to detect antibodies, ensuring precise results. TrueHealthLabs.com partners with CLIA-certified laboratories to uphold rigorous testing standards for dependable results.


Medical Review Board

Reviewed by Jeff Donohue M.D. from Body Logic and Brady Hurst DC, CCCN. Written by True Health Lab’s team of editorial health contributors.

Disclaimer: This information is for educational purposes only and not intended as medical advice. Consult your healthcare provider for personalized guidance.


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