Ordering the Estrogen Metabolism Assessment, Urine | New York
Ordering the Estrogen Metabolism Assessment, Urine helps measure how your body breaks down estrogen, which can affect symptoms like breast tenderness, mood changes, and weight gain. This test checks for specific estrogen byproducts in urine, giving clear information about hormone balance and possible risks for conditions like fibroids or endometriosis. Interestingly, research shows that certain estrogen breakdown products may be linked to a higher risk of some cancers, making this test useful for those wanting to understand their hormone patterns more deeply.
When ordering this test, you gain access to several specific benefits:
- Measures both protective and potentially harmful estrogen byproducts for a more complete hormone profile.
- Helps identify imbalances that may contribute to symptoms like bloating, headaches, or irregular cycles.
- Supports targeted treatment plans for hormone-related conditions such as PMS, menopause, or polycystic ovary syndrome.
- Assists in monitoring the effectiveness of hormone therapy or lifestyle changes.
- Provides a non-invasive way to track changes in estrogen metabolism over time.
Who Should Consider Hormone Metabolite Testing
People who have ongoing symptoms like unexplained fatigue, mood swings, or changes in menstrual cycles may benefit from this test. For example, someone experiencing new hair loss, persistent bloating, and trouble sleeping might find that checking their estrogen breakdown products helps pinpoint the cause and guide next steps.
Ordering this test may also be helpful in these situations:
- Experiencing breast tenderness or fibroids that have not improved with other treatments
- Having a family history of hormone-sensitive cancers and wanting to check for risk factors
- Struggling with infertility or irregular periods despite other normal lab results
- Managing menopause symptoms like hot flashes or night sweats
- Noticing changes in cholesterol or cardiovascular markers that could be linked to hormone shifts
Testing for estrogen breakdown products can help identify patterns that may be missed with standard hormone tests, allowing for more targeted support and monitoring. Delaying this test could mean missing early signs of hormone imbalance, which may make it harder to address symptoms or prevent future complications.
Preparing for Urine Hormone Analysis
Fasting is not required for this urine-based test, but be sure to collect your sample according to the instructions in your test kit. Always follow any directions your doctor or healthcare provider gives you to make sure your sample is collected correctly and your results are as useful as possible.
Labs Included When Ordering Your Estrogen Metabolism Assessment, Urine
| Test Name | Reference Range | What This Marker Means | Low and High Levels of Estrogen Metabolism Assessment, Urine |
|---|---|---|---|
| Creatinine | 0.3 – 3.0 | Creatinine is used to check if your urine sample is concentrated enough for accurate hormone measurement. It helps adjust results for differences in urine dilution. |
High levels mean your urine is very concentrated, which can affect hormone readings.
Low levels mean your urine is too diluted, possibly making hormone results less clear. |
| 2-Hydroxyestrone | 0.8 – 3.3 | 2-Hydroxyestrone is a breakdown product of estrogen that is considered more protective. It shows how your body processes estrogen through a specific pathway. |
High levels mean your body is making more of the protective estrogen byproduct.
Low levels mean your body may not be using the protective pathway as much. |
| 16 a-hydroxyestrone | 0.5 – 2.5 | 16 a-hydroxyestrone is another estrogen byproduct, but higher amounts may be linked to increased risk for certain hormone-related conditions. |
High levels mean your body is making more of this byproduct, which may be linked to higher risk for some conditions.
Low levels mean your body is making less of this byproduct, which is often considered favorable. |
| 2:16 Ratio | 1.5 – 3.0 | The 2:16 ratio compares the amounts of protective and potentially harmful estrogen byproducts. A higher ratio is generally considered more favorable for hormone balance. |
High levels mean you have more protective estrogen byproducts compared to potentially harmful ones.
Low levels mean you have more of the potentially harmful byproduct compared to the protective one. |
Reference ranges may change slightly as labs update their methods and guidelines.
Estrogen Metabolism Assessment, Urine FAQ
Is there Estrogen Metabolism Assessment, Urine testing near me?
This is a test kit you can use at home, and you can find a local draw location using the link at the top of the page. For those dealing with symptoms like breast tenderness or hormone-related mood changes, having a nearby collection site makes it easier to get tested quickly and comfortably.
How do I interpret the test results?
While your treating physician should review your results, you can also schedule a one-on-one test results review with our clinical team for a detailed explanation and next steps.
What is the cost of the test?
The price listed for this test includes standard shipping to you and return shipping to the lab, but draw fees may apply. Ordering this test can help you address hormone-related symptoms sooner, which may lead to faster relief and more targeted treatment.
How often should I retest?
Retesting is usually recommended every 6 to 12 months, especially if you are making changes to your hormone therapy or lifestyle. Regular testing helps track progress and adjust your plan based on measurable changes in hormone breakdown.
How accurate is the test?
This test uses liquid chromatography-tandem mass spectrometry (LC-MS/MS) for precise measurement of estrogen metabolites, with a specificity of 98% and sensitivity of 97%. TrueHealthLabs.com partners with CLIA-certified and CAP-certified laboratories to uphold rigorous testing standards for dependable results.
Important Notes
None.
Medical Review Board
Reviewed by Jeff Donohue M.D. from Body Logic and Brady Hurst DC, CCCN. Written by True Health Lab’s team of editorial health contributors.
Disclaimer: This information is for educational purposes only and not intended as medical advice. Consult your healthcare provider for personalized guidance.
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