Ordering the Estrogen Metabolism Assessment, Serum | New York
Ordering the Estrogen Metabolism Assessment, Serum helps measure how your body processes estrogen, which can affect symptoms like irregular periods, mood changes, and weight gain. This test checks for two main estrogen breakdown products, giving a clear picture of hormone balance and possible risks for conditions like fibroids or endometriosis. Interestingly, research shows that certain estrogen metabolites may be linked to bone strength and not just hormone symptoms.
When ordering this test, you can expect these specific benefits:
- Identifies if your body is making more of the “good” or “bad” estrogen byproducts
- Helps pinpoint hormone imbalances that may be causing symptoms like bloating or breast tenderness
- Supports decisions about hormone therapy or supplements
- Assists in tracking changes after starting a new diet or lifestyle plan
- Provides data that can help lower risk for hormone-related conditions
Who Should Consider Hormone Metabolite Testing
People who have ongoing symptoms like heavy periods, unexplained fatigue, or mood swings may benefit from this test. For example, someone who has tried different treatments for PMS but still struggles with headaches and breast tenderness could use this test to find out if estrogen breakdown is part of the problem.
Ordering this test may also be helpful in these situations:
- Experiencing hot flashes or night sweats during menopause
- Dealing with infertility or trouble getting pregnant
- Managing endometriosis or fibroids
- Having a family history of hormone-related cancers
- Noticing changes in bone strength or density, which can be connected to certain estrogen metabolites
Testing for estrogen breakdown products can show if your body is making more of the types linked to symptoms or risks, helping you and your doctor make targeted changes. Delaying this test could mean missing early signs of hormone imbalance, which may make it harder to manage symptoms or prevent future problems.
Preparing for Hormone Metabolite Lab Work
Fasting is not required for this test, but always check your test kit instructions for any special steps. Make sure to follow whatever guidance your doctor or healthcare practitioner gives you, as this helps ensure your sample is collected the right way.
Labs Included When Ordering Your Estrogen Metabolism Assessment, Serum
| Test Name | Reference Range | What This Biomarker Means | Low and High Levels of Estrogen Metabolism Assessment, Serum |
|---|---|---|---|
| 2-Hydroxyestrone | 0.4 – 3.0 | 2-Hydroxyestrone is a breakdown product of estrogen that is often called the “protective” metabolite. It is linked to lower risk for hormone-related conditions and helps show if your body is processing estrogen in a way that is considered safer. |
High levels mean your body is making more of the protective estrogen byproduct, which is usually a good sign.
Low levels mean your body may not be making enough of the protective type, which could be linked to higher risk for certain hormone-related symptoms. |
| 16a-Hydroxyestrone | 0.2 – 1.2 | 16a-Hydroxyestrone is another estrogen breakdown product, sometimes called the “aggressive” metabolite. Higher levels are linked to symptoms like breast tenderness and may be connected to higher risk for hormone-driven conditions. |
High levels mean your body is making more of the aggressive estrogen byproduct, which can be linked to symptoms or higher risk for hormone-related issues.
Low levels mean your body is making less of this type, which is usually considered better for hormone balance. |
Reference ranges may change slightly as labs update their methods and research advances.
Estrogen Metabolism Assessment FAQ
Is there Estrogen Metabolism Assessment, Serum testing near me?
This test is available as a kit that you can use at a local draw site—check the draw location link at the top of the page. For people dealing with symptoms like irregular periods or hormone imbalance, having a nearby collection site makes it easier to get tested quickly and start finding answers.
How do I interpret the test results?
While your treating physician should always review your results, you can also use our one-on-one test results review service with our clinical team for a detailed explanation and next steps.
What is the cost of the test?
The price you see includes standard shipping to you and back to the lab, but local draw fees may apply. Ordering this test can help you find out if hormone metabolism is behind symptoms like fatigue or mood changes, so you can start targeted treatment sooner.
How often should I retest?
Retesting is usually recommended every 6 to 12 months, especially if you are starting or changing hormone therapy, supplements, or lifestyle plans. Regular testing helps track changes in estrogen breakdown and supports better symptom management.
How accurate is the test?
This test uses high-performance liquid chromatography with tandem mass spectrometry (LC-MS/MS), which is known for its high precision. The specificity is 98% and sensitivity is 97%. TrueHealthLabs.com partners with CLIA-certified and CAP-certified laboratories to uphold rigorous testing standards for dependable results.
Medical Review Board
Reviewed by Jeff Donohue M.D. from Body Logic and Brady Hurst DC, CCCN. Written by True Health Lab’s team of editorial health contributors.
Disclaimer: This information is for educational purposes only and not intended as medical advice. Consult your healthcare provider for personalized guidance.
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