Ordering the Estrogen Metabolism Assessment, Serum
Ordering the Estrogen Metabolism Assessment, Serum helps measure how your body processes estrogen, which can affect symptoms like bloating, mood changes, and irregular periods. This test checks for two main estrogen breakdown products in your blood, giving clear information about hormone balance and possible risks for conditions like fibroids or endometriosis. Interestingly, research shows that certain patterns in estrogen metabolism may be linked to bone strength and the risk of osteoporosis, making this test useful for more than just hormone-related symptoms.
When ordering the Estrogen Metabolism Assessment, Serum, you can expect these specific benefits:
- Identifies if your body is breaking down estrogen in a way that may increase risk for fibroids or endometriosis.
- Helps pinpoint hormone imbalances that may be causing symptoms like breast tenderness, headaches, or weight gain.
- Supports fertility planning by revealing estrogen patterns that can affect ovulation and menstrual cycles.
- Assists in monitoring hormone changes during menopause or perimenopause.
- Provides data to help guide treatment for PMS, PCOS, or unexplained fatigue.
Who Should Consider Hormone Metabolite Testing
People who have been struggling with unexplained symptoms such as persistent bloating, mood swings, or irregular periods may find this test helpful. For example, someone who has tried different treatments for acne or hair loss without success might discover that hormone metabolism is playing a role.
Ordering this test may also be helpful in these situations:
- Experiencing ongoing breast tenderness or water retention that does not improve with dietary changes.
- Having a family history of hormone-related conditions like fibroids or endometriosis.
- Trying to conceive and facing unexplained infertility or irregular cycles.
- Managing symptoms of menopause, such as hot flashes or night sweats, and wanting to track hormone changes.
- Noticing changes in bone strength or density, as certain estrogen metabolites can influence bone health.
This test is recommended for those who want to measure how their body processes estrogen, which can help target the cause of symptoms like fatigue, mood changes, or menstrual problems. Delaying this test may mean missing the chance to address hormone imbalances early, which could make symptoms harder to manage over time.
How to Prepare for Hormone Metabolite Blood Testing
Fasting is not required for the Estrogen Metabolism Assessment, Serum, but always check the test kit instructions for any special steps. Make sure to follow whatever guidance your doctor or healthcare practitioner gives you, as this helps ensure your sample is collected correctly and your results are as useful as possible.
Labs Included When Ordering Your Estrogen Metabolism Assessment, Serum
| Test Name | Reference Range | What This Biomarker Means | Low and High Levels of Estrogen Metabolism Assessment, Serum |
|---|---|---|---|
| 2-Hydroxyestrone | 0.4 – 3.0 | 2-Hydroxyestrone is a breakdown product of estrogen that is considered less active and may be protective against certain hormone-related conditions. It helps show if your body is processing estrogen in a way that lowers risk for some symptoms and diseases. |
High levels mean your body is making more of the less active form of estrogen, which may lower risk for some hormone-driven conditions.
Low levels mean your body may be making more of the active forms of estrogen, which could increase risk for symptoms like breast tenderness or fibroids. |
| 16a-Hydroxyestrone | 0.2 – 1.2 | 16a-Hydroxyestrone is another estrogen breakdown product that is more active and can stimulate tissue growth. Tracking this marker helps identify if your estrogen metabolism may be linked to symptoms like heavy periods or increased risk for certain conditions. |
High levels mean your body is making more of the active form of estrogen, which may be linked to symptoms like heavy periods or fibroids.
Low levels mean your body is making less of this active form, which may lower risk for some hormone-related symptoms. |
Reference ranges may change slightly as labs update their methods and guidelines.
Estrogen Metabolism Assessment, Serum FAQ
Is there Estrogen Metabolism Assessment, Serum testing near me?
This test is available as a kit that you can use at a local draw site—check the draw location link at the top of the page. For people dealing with symptoms like irregular periods or hormone-related headaches, having a nearby collection site makes it easier to get tested quickly and start finding answers.
How do I interpret the test results?
While your treating physician should review your results, you can also use our one-on-one test results review service with our clinical team for a detailed explanation and next steps.
What is the cost of the test?
The price listed for the test includes standard shipping to you and return shipping to the lab, but draw fees may apply at your local collection site. Ordering this test can help you address hormone-related symptoms sooner, which may help you feel better faster.
How often should I retest?
Retesting is usually recommended every 6 to 12 months, especially if you are starting or changing hormone treatments or if your symptoms change. Regular testing helps track how your body processes estrogen over time and supports more targeted treatment.
How accurate is the test?
This test uses high-performance liquid chromatography with tandem mass spectrometry (LC-MS/MS), which is known for its high specificity (98%) and sensitivity (97%) in measuring estrogen metabolites. TrueHealthLabs.com partners with CLIA-certified and CAP-certified laboratories to uphold rigorous testing standards for dependable results.
Important Notes
None.
Medical Review Board
Reviewed by Jeff Donohue M.D. from Body Logic and Brady Hurst DC, CCCN. Written by True Health Lab’s team of editorial health contributors.
Disclaimer: This information is for educational purposes only and not intended as medical advice. Consult your healthcare provider for personalized guidance.
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