Ordering the Comprehensive Female Hormone Saliva Test (Rhythm Plus) | Europe
Ordering the Comprehensive Female Hormone Saliva Test (Rhythm Plus) helps map hormone changes throughout the menstrual cycle, providing a detailed look at estrogen, progesterone, testosterone, cortisol, DHEA, and melatonin. This test uses multiple saliva samples over the month, which can reveal hormone patterns that single-sample tests may miss. Interestingly, research shows that hormone levels can shift significantly even within a single day, making multi-sample testing more informative for those with ongoing symptoms.
Ordering this test offers several specific benefits:
- Tracks hormone changes across the entire menstrual cycle, not just one day
- Helps identify hormone imbalances linked to symptoms like irregular periods, fatigue, and mood changes
- Supports targeted treatment for conditions such as PMS, endometriosis, and polycystic ovary syndrome
- Reduces the risk of unnecessary medication by pinpointing the root cause of symptoms
- Provides a clear hormone map to guide fertility planning or address unexplained infertility
Who Should Consider Female Hormone Imbalance Testing
People who experience ongoing symptoms like bloating, breast tenderness, mood swings, or irregular cycles may benefit from this test. For example, someone who has tried different treatments for acne or hair loss without success might find that hormone mapping uncovers a pattern missed by standard tests.
Ordering this test may also be helpful in these situations:
- Experiencing night sweats or hot flashes before menopause
- Struggling with unexplained weight gain or low libido
- Dealing with persistent fatigue or trouble sleeping
- Managing symptoms of endometriosis or fibroids
- Noticing that anxiety or depression worsens at certain times of the month, which can be linked to hormone shifts
Testing for hormone patterns can help clarify the cause of symptoms like irregular cycles, mood changes, or unexplained fatigue, allowing for more targeted treatment. Delaying this test may mean missing the window to catch hormone fluctuations that only show up at certain times, which could slow down finding the right solution.
Preparing for Saliva Hormone Panel Collection
Fasting is not required for this saliva-based test, but you should follow the timing and collection instructions included in your kit. Always go by any directions your doctor or healthcare provider gives you to make sure your samples are collected correctly and your results are as useful as possible.
Labs Included When Ordering Your Comprehensive Female Hormone Saliva Test (Rhythm Plus)
| Test Name | Reference Range | Significance | Low and High Levels of Comprehensive Female Hormone Saliva Test (Rhythm Plus) |
|---|---|---|---|
| Female Hormones | |||
| Progesterone (free) 12x | Luteal phase: 75-270 | Progesterone is a key hormone for regulating the menstrual cycle and supporting pregnancy. Tracking it throughout the cycle helps identify luteal phase defects or imbalances. |
High levels mean possible ovarian cysts or hormone therapy effects.
Low levels mean possible ovulation problems or luteal phase deficiency. |
| Estrogen (free estradiol) 12x | Follicular: 1.3-3.3, Luteal: 2.0-5.5 | Estradiol is the main estrogen in women and is important for ovulation, bone strength, and mood. Measuring it at different times shows if levels are too high or low during the cycle. |
High levels mean possible estrogen dominance, risk for fibroids, or endometriosis.
Low levels mean possible ovarian insufficiency or missed ovulation. |
| Testosterone (free) 12x | 16-55 | Testosterone supports muscle strength, mood, and libido. Testing it throughout the cycle can help explain symptoms like hair loss or acne. |
High levels mean possible polycystic ovary syndrome or adrenal issues.
Low levels mean possible low energy, reduced libido, or muscle weakness. |
| Progesterone / Estrogen Ratio | Luteal phase: 100-500 | This ratio helps show if estrogen and progesterone are balanced. An imbalance can cause symptoms like PMS, mood swings, or irregular cycles. |
High levels mean possible progesterone dominance or low estrogen.
Low levels mean possible estrogen dominance or low progesterone. |
| Adrenal and Sleep Hormones | |||
| Cortisol 4x (free) | Morning: 3.7-9.5, Noon: 1.2-3.0, Evening: 0.6-1.9, Night: 0.4-1.0 | Cortisol is the main stress hormone and should follow a daily pattern. Testing it four times a day shows if stress or adrenal fatigue is affecting hormone balance. |
High levels mean possible chronic stress, adrenal overactivity, or sleep problems.
Low levels mean possible adrenal fatigue or low stress response. |
| Melatonin (free) | Night: 10-80 | Melatonin controls sleep and wake cycles. Testing it at night can help explain trouble falling or staying asleep. |
High levels mean possible excessive sleepiness or disrupted sleep-wake rhythm.
Low levels mean possible insomnia or poor sleep quality. |
| DHEA | 2.0-10.0 | DHEA is made by the adrenal glands and helps make other hormones. It supports energy, mood, and immune function. |
High levels mean possible adrenal overactivity or polycystic ovary syndrome.
Low levels mean possible adrenal fatigue or low hormone production. |
| Cycle Mapping | |||
| Month-long chart of hormone pattern | N/A | This chart shows how hormone levels change each day of the cycle. It helps spot patterns that may be linked to symptoms or fertility issues. |
High levels mean possible hormone surges or imbalances at certain times.
Low levels mean possible missed ovulation or hormone drops. |
Reference ranges may change slightly as labs update their standards, so always check your report for the most current values.
Comprehensive Female Hormone Saliva Test (Rhythm Plus) FAQ
Is there Comprehensive Female Hormone Saliva Test (Rhythm Plus) testing near me?
This is a home test kit, so you can collect your saliva samples locally and send them to the lab using the included prepaid shipping; check the draw location link at the top of the page for more details. For those with symptoms like irregular cycles or hormone-related fatigue, being able to collect samples at home makes it easier to capture hormone changes at the right times without extra travel.
How do I interpret the test results?
While your treating physician should review your results, we also offer a one-on-one test results review with our clinical team to help you understand your hormone patterns and what they mean for your symptoms.
What is the cost of the test?
The price you see includes standard shipping to you and return shipping to the lab, though local draw fees may apply. Ordering this test can help you find the cause of symptoms like PMS or unexplained fatigue, so you can start targeted treatment sooner.
How often should I retest?
Retesting is usually recommended every 6-12 months, or after any major change in symptoms or treatment, to track how your hormone patterns respond over time and adjust your care as needed.
How accurate is the test?
This test uses saliva samples analyzed by enzyme immunoassay (EIA), with a specificity of 98% and sensitivity of 96% for hormone detection. TrueHealthLabs.com partners with CLIA-certified and CAP-certified laboratories to uphold rigorous testing standards for dependable results.
Important Notes
- This test is for women who are still cycling and is not intended for those who are post-menopausal.
- These tests are available for European countries only.
Medical Review Board
Reviewed by Jeff Donohue M.D. from Body Logic and Brady Hurst DC, CCCN. Written by True Health Lab’s team of editorial health contributors.
Disclaimer: This information is for educational purposes only and not intended as medical advice. Consult your healthcare provider for personalized guidance.
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