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Complement C1 Esterase Inhibitor Serum Test


  • Draw Locations
  • Turnaround Time: 2-4 Business Days on Average. Time may vary.
  • Not Available in: NY, NJ, MA, and RI
  • HSA and FSA Approved

$139.00 USD $327.84

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Ordering the Complement C1 Esterase Inhibitor Serum Test

Ordering the Complement C1 Esterase Inhibitor Serum Test is crucial for diagnosing hereditary angioedema, a condition that can cause sudden swelling in various parts of the body. Interestingly, this test can also help identify acquired forms of angioedema, which are less common but equally important to diagnose.

Here are some specific benefits of this lab test:

  • Helps in diagnosing hereditary angioedema.
  • Assists in identifying acquired angioedema.
  • Provides insights into unexplained swelling episodes.
  • Guides treatment plans for angioedema.
  • Monitors the effectiveness of ongoing treatments.

Who Should Consider the Test

Individuals experiencing unexplained swelling episodes, especially if they have a family history of similar symptoms, should consider this test. For example, a person who notices recurring swelling in their hands and face without any apparent cause might find this test beneficial.

Other scenarios where this test might be considered include:

  • Family history of hereditary angioedema.
  • Unexplained abdominal pain episodes.
  • Recurrent swelling after minor injuries.
  • Swelling episodes triggered by stress or trauma.
  • Unexpected connection: unexplained voice changes due to throat swelling.

Ordering this test can provide clarity and guide treatment, while not ordering might leave symptoms unexplained and untreated.

Preparing for the Test

Fasting is not required for this test. It’s important to follow your doctor’s instructions regarding any medications or supplements you are taking.

Labs Included When Ordering Your Complement C1 Esterase Inhibitor Serum Test

Test Name Reference Range Significance Low and High Levels of Complement C1 Esterase Inhibitor
Complement C1 Esterase Inhibitor 21-39 This biomarker helps in diagnosing hereditary and acquired angioedema. It measures the level of a protein that regulates the complement system, which is part of the immune response. High levels mean potential inflammation or infection.

Low levels mean possible hereditary angioedema.

Reference ranges can vary, so it’s wise to check the Quest Diagnostics lab test directory for the most current information.


Complement C1 Esterase Inhibitor Serum Test FAQ

Is there Complement C1 Esterase Inhibitor Serum Test testing near me?

You can find nearby draw locations with our patient service center locator, which also offers mobile phlebotomy options. During the collection, a skilled technician will guide you through the process, ensuring a smooth experience.

What is the cost of the test?

The cost of the Complement C1 Esterase Inhibitor Serum Test can be found at the top of the page. Pricing includes collection fees when visiting patient service centers, ensuring no hidden costs.

How often should I retest?

Retesting is generally recommended every 6 to 12 months, especially if you have ongoing symptoms or are monitoring treatment effectiveness. Regular testing helps in managing and adjusting treatment plans effectively.

How accurate is the test?

The test uses a specific method called nephelometry to measure protein levels, ensuring precise results. TrueHealthLabs.com only partners with CLIA certified labs, emphasizing the reliability of the testing process.


Medical Review Board

Reviewed by Jeff Donohue M.D. from Body Logic and Brady Hurst DC, CCCN. Written by True Health Lab’s team of editorial health contributors.

Disclaimer: This information is for educational purposes only and not intended as medical advice. Consult your healthcare provider for personalized guidance.


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