Ordering the Blood-Brain Barrier Permeability Test | Cyrex Array #20
Ordering the Blood-Brain Barrier Permeability Test | Cyrex Array #20 helps check if the barrier between your blood and brain is working as it should. This test looks for specific proteins that can show if the barrier is letting things through that should not pass, which can be linked to symptoms like brain fog, memory problems, or trouble focusing. Interestingly, research shows that changes in blood-brain barrier proteins can appear before symptoms of neurological issues are noticed, making early testing useful for tracking changes over time.
When ordering this test, you can expect these specific benefits:
- Detects early signs of blood-brain barrier changes before symptoms become severe
- Helps identify possible links between gut issues and brain symptoms
- Supports monitoring of brain inflammation in people with autoimmune conditions
- Assists in tracking the impact of food sensitivities on brain function
- Provides clear markers to guide next steps with your healthcare provider
Who Should Consider Brain Barrier Protein Testing
People who have ongoing brain fog, unexplained headaches, or memory lapses may benefit from this test. For example, someone who has been struggling with concentration and forgetfulness after a period of high stress or illness might find answers by checking for changes in their blood-brain barrier proteins.
Ordering this test may also be helpful in these situations:
- Experiencing new or worsening balance or coordination problems
- Having chronic fatigue that does not improve with rest
- Dealing with mood swings or depression that do not respond to usual treatments
- Managing autoimmune disorders with new neurological symptoms
- Noticing increased sensitivity to foods after a gut infection, which can sometimes affect the brain barrier
Testing for these markers can help pinpoint if brain symptoms are linked to changes in the blood-brain barrier, which can guide more targeted care. Delaying this test could mean missing early signs of barrier changes, making it harder to track and manage symptoms as they develop.
Preparing for Blood-Brain Barrier Protein Screening
Fasting is not required for this test, but always review the kit instructions for any special steps before your blood draw. Make sure to follow whatever guidance your doctor or healthcare practitioner gives you, as this can help ensure your sample is collected and processed correctly.
Labs Included When Ordering Your Blood-Brain Barrier Permeability Test | Cyrex Array #20
| Test Name | Reference Range | What This Marker Means | Low and High Levels of Blood-Brain Barrier Permeability Test | Cyrex Array #20 |
|---|---|---|---|
| Blood-Brain Barrier Protein IgA + IgG | IgA: < 30 IgG: < 30 |
These antibodies show if the immune system is reacting to blood-brain barrier proteins. High levels can mean the barrier is letting unwanted substances into the brain. |
High levels mean the immune system is reacting to the blood-brain barrier, which may signal increased permeability or inflammation.
Low levels mean there is little or no immune response to the barrier proteins, which is usually expected. |
| Blood-Brain Barrier Protein IgM | IgM: < 30 | This marker checks for a recent or ongoing immune response to blood-brain barrier proteins. It can help show if the barrier has been recently affected. |
High levels mean there may be a new or active immune response against the blood-brain barrier, possibly from a recent trigger.
Low levels mean there is no current immune response, which is generally a normal finding. |
Reference ranges may change slightly if the lab updates their standards or methods.
Blood-Brain Barrier Permeability Test | Cyrex Array #20 FAQ
Is there Blood-Brain Barrier Permeability Test | Cyrex Array #20 testing near me?
This test is a kit that you can use at a local blood draw site—check the draw location link at the top of the page for options close to you. For people dealing with symptoms like brain fog or memory issues, having a nearby collection site makes it easier to get tested without extra travel or delays.
How do I interpret the test results?
While your treating physician should review your results, we also offer a one-on-one test results review with our clinical team to help you understand what your results mean and what steps to take next.
What is the cost of the test?
The price listed for this test includes standard shipping to you and back to the lab, but draw fees may apply at the collection site. Ordering this test can help you find out if blood-brain barrier changes are linked to your symptoms, which may help you get answers and support more quickly.
How often should I retest?
Retesting is usually recommended every 6 to 12 months, especially if you are tracking changes in symptoms or monitoring treatment progress. Regular testing can help you and your provider see if your blood-brain barrier markers are improving or if new changes are happening.
How accurate is the test?
This test uses ELISA (enzyme-linked immunosorbent assay) to measure antibodies against blood-brain barrier proteins, with a specificity of 98% and sensitivity of 97%. TrueHealthLabs.com partners with CLIA-certified and CAP-certified laboratories to uphold rigorous testing standards for dependable results.
Important Notes
- It is recommended to be clear of immunosuppressants and/or corticosteroids for at least 60 days prior to taking this test. Please consult with your prescribing healthcare provider.
- NOT AVAILABLE IN NEW YORK. SPECIMEN DRAWS CAN BE COMPLETED IN NEIGHBORING STATES.
- We are now accepting international orders. Sample must be received within 7 days. Additional return shipping fees may apply.
- READ: IMPORTANT Cyrex FAQs
- Due to circumstances beyond our control, pediatric blood draws are not included under Cyrex’s contracted phlebotomy. All patients 15 years of age and younger are included in the pediatric group. Pediatric blood draws must be scheduled by the parents at a laboratory of their choosing, and must be paid for by the parent at the time of service.
Medical Review Board
Reviewed by Jeff Donohue M.D. from Body Logic and Brady Hurst DC, CCCN. Written by True Health Lab’s team of editorial health contributors.
Disclaimer: This information is for educational purposes only and not intended as medical advice. Consult your healthcare provider for personalized guidance.
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