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Bartonella IgXSpot Test


  • Draw Locations
  • Processed by IgeneX
  • Turnaround Time: 5-8 Business Days on Average. Time may vary.
  • Not Available in: NY
  • HSA and FSA Approved

$459.00 USD $969.00

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Ordering the Bartonella IgXSpot Test

The Bartonella IgXSpot Test helps detect immune responses to Bartonella bacteria, which are linked to symptoms like fatigue, joint pain, and neurological changes. This test is especially useful for people who have unexplained symptoms that may be related to Bartonella infection, such as those seen in cat scratch fever or chronic neurological issues. Interestingly, the Bartonella IgXSpot Test can identify T-cell responses even when antibody levels are low, which means it may detect infections that other tests miss.

Ordering this test provides several specific benefits:

  • Detects both recent and ongoing Bartonella infections by measuring T-cell activity.
  • Helps clarify the cause of persistent symptoms when other tests are inconclusive.
  • Supports targeted treatment decisions by confirming Bartonella involvement.
  • Reduces the risk of misdiagnosis by providing a more complete immune response profile.
  • Offers a non-invasive blood collection process with a convenient at-home kit.

Who Should Consider Bartonella Immune Response Testing

People who have been feeling unusually tired, have unexplained joint or muscle pain, or experience neurological symptoms like confusion or memory loss may benefit from this test. For example, someone who has had ongoing headaches, dizziness, and mood changes after a cat scratch or tick bite might find answers through this testing.

Ordering this test may also be helpful in these situations:

  • Persistent fever and swollen lymph nodes after animal exposure.
  • Unexplained skin rashes or lesions that do not improve with standard care.
  • Chronic sleep problems paired with irritability and concentration issues.
  • Heart rhythm changes or chest discomfort with no clear cause.
  • People with liver or spleen issues that have not been explained by other tests, as Bartonella can sometimes affect these organs.

Testing for Bartonella infection can help pinpoint the reason for ongoing symptoms, allowing for more focused treatment and monitoring. Delaying this test could mean missing the chance to address an infection before it leads to more complex or long-lasting problems.

Preparing for Bartonella T-Cell Response Testing

Fasting is not required before taking the Bartonella IgXSpot Test, so you can eat and drink as usual. Always follow any instructions your doctor or healthcare provider gives you to make sure your sample is collected and processed correctly.

Labs Included When Ordering Your Bartonella IgXSpot Test

Test Name Reference Range What This Biomarker Means Low and High Levels of Bartonella IgXSpot
Bartonella IgXSpot (Enzyme-Linked ImmunoSpot Assay) 0–4 spots (Negative)
5–7 spots (Indeterminate)
8+ spots (Positive)
This test measures the number of T-cells that react to Bartonella antigens, showing if your immune system is actively responding to the bacteria. It helps identify both current and past Bartonella infections, even when antibody tests are negative. High levels mean your immune system is actively fighting Bartonella, suggesting a current or recent infection.

Low levels mean there is little or no immune response to Bartonella, making an active infection less likely.

Reference ranges may change slightly as labs update their methods or as new research becomes available. Always check your report for the most current information.


Bartonella IgXSpot Test FAQ

Is there Bartonella IgXSpot testing near me?

This is an at-home test kit, and your blood sample can be collected at a local draw site—check the draw location link at the top of the page. For people dealing with symptoms like fatigue or neurological changes, having a nearby collection option makes it easier to get tested quickly and start finding answers.

How do I interpret the test results?

While your treating physician should always review your results, you can also use our one-on-one test results review service with our clinical team for a detailed explanation and next steps.

What is the cost of the test?

The price listed for the Bartonella IgXSpot Test includes standard shipping to you and return shipping to the lab; draw fees may apply. Ordering this test can help you identify if Bartonella is causing your symptoms, which may help you get the right treatment sooner.

How often should I retest?

Retesting is usually recommended every 3–6 months if you are being treated for Bartonella or if symptoms persist, so you can track changes in your immune response and adjust your care as needed.

How accurate is the test?

The Bartonella IgXSpot Test uses the Enzyme-Linked ImmunoSpot (ELISPOT) method, which detects T-cell responses with a sensitivity of 90% and specificity of 95%. TrueHealthLabs.com partners with CLIA-certified and CAP-certified laboratories to uphold rigorous testing standards for dependable results.


Medical Review Board

Reviewed by Jeff Donohue M.D. from Body Logic and Brady Hurst DC, CCCN. Written by True Health Lab’s team of editorial health contributors.

Disclaimer: This information is for educational purposes only and not intended as medical advice. Consult your healthcare provider for personalized guidance.


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