Ordering the Comprehensive Melatonin Profile
The Comprehensive Melatonin Profile helps you measure your melatonin levels at different times, giving a clear picture of your sleep-wake cycle. This test is often used to check for sleep issues, trouble falling asleep, or waking up too early. Interestingly, melatonin levels can also be affected by working night shifts or traveling across time zones, which can disrupt your natural sleep rhythm.
Ordering this test can help you:
- Identify if your melatonin production is too low or too high at certain times of day or night
- Pinpoint possible causes of sleep disruption, such as delayed or advanced sleep phase
- Track how your body responds to light exposure, shift work, or travel
- Monitor the effects of sleep aids or supplements on your natural melatonin cycle
- Support your doctor in making decisions about sleep therapy or lifestyle changes
Who Should Consider Melatonin Rhythm Testing
People who struggle to fall asleep at night, wake up too early, or feel tired during the day may benefit from this test. For example, someone who works rotating shifts and finds it hard to adjust their sleep schedule may want to know if their melatonin levels are out of sync.
Ordering this test may also be helpful in these situations:
- Difficulty adjusting to a new time zone after long-distance travel
- Restlessness or frequent waking during the night
- Persistent fatigue despite getting enough sleep
- Children or teens with delayed sleep patterns
- People with chronic headaches, as melatonin imbalance can sometimes play a role
Testing your melatonin rhythm can reveal if your body’s natural sleep signals are off, which can help you and your doctor make targeted changes to improve your sleep. Delaying this test may mean missing the chance to address sleep problems before they become more difficult to manage.
How to Prepare for the Test
Fasting is not required for this test, but you should follow the specific timing instructions provided in your test kit for accurate results. Make sure to carefully read and follow any directions your doctor or healthcare provider gives you, as these can affect your sample collection and the usefulness of your results.
Labs Included When Ordering Your Comprehensive Melatonin Profile
| Test Name | Reference Range | What This Measures | Low and High Levels of Comprehensive Melatonin Profile |
|---|---|---|---|
| Melatonin (Saliva) |
Night (2-4am): 10-60 Morning (6-8am): 1-10 Afternoon (2-4pm): <3 Evening (10pm-midnight): 3-25 |
Melatonin is a hormone that helps control your sleep and wake cycles. This test measures how much melatonin your body makes at different times of the day and night. |
High levels mean your body may be producing too much melatonin, which can cause excessive sleepiness or trouble waking up.
Low levels mean your body may not be making enough melatonin, which can lead to trouble falling asleep or staying asleep. |
Reference ranges may change slightly as labs update their methods and guidelines.
Comprehensive Melatonin Profile FAQ
Is there Comprehensive Melatonin Profile testing near me?
This is a home test kit that you can collect yourself, and you can check the draw location link at the top of the page for more details. For those struggling with sleep issues or irregular schedules, having a convenient way to collect your sample at home makes it easier to get answers without extra travel or waiting.
How do I interpret the test results?
While your treating physician should review your results, we also offer a one-on-one test results review with our clinical team to help you understand what your numbers mean and what steps you can take next.
What is the cost of the test?
The price you see for the test includes standard shipping to you and return shipping to the lab, but draw fees may apply. Ordering this test can help you address sleep problems sooner, so you can start working on solutions that fit your needs.
How often should I retest?
It’s best to retest every 3 to 6 months, especially if you are making changes to your sleep routine or using supplements, so you can track your progress and adjust your plan as needed.
How accurate is the test?
This test uses a saliva sample analyzed by enzyme-linked immunosorbent assay (ELISA), with a specificity of 98% and sensitivity of 97%. TrueHealthLabs.com works with CLIA-certified and CAP-certified labs to maintain high-quality testing standards you can trust.
Medical Review Board
Reviewed by Jeff Donohue M.D. from Body Logic and Brady Hurst DC, CCCN. Written by True Health Lab’s team of editorial health contributors.
Disclaimer: This information is for educational purposes only and not intended as medical advice. Consult your healthcare provider for personalized guidance.
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