Ordering the Total Salivary, sIgA (Single Test)
Measuring total salivary secretory immunoglobulin A (sIgA) helps identify how your body’s first line of immune defense is working in your mouth and digestive tract. This test is often used to check for immune system changes related to stress, gut health, and chronic infections. Interestingly, sIgA levels can also reflect how your body responds to emotional stress, not just physical illness or infection.
Ordering this test can help you:
- Track immune response in the mouth and digestive system.
- Monitor changes in immune function during periods of stress or illness.
- Identify possible immune suppression or overactivity linked to gut or oral issues.
- Support decisions about natural remedies or lifestyle changes for immune support.
- Detect early signs of immune imbalance before symptoms become more noticeable.
Who Should Consider Secretory Antibody Screening
People who often deal with frequent colds, digestive discomfort, or unexplained mouth irritation may benefit from this test. For example, someone who has been feeling run down with ongoing sinus congestion and mild stomach upset might want to check if their immune system is responding as expected.
Ordering this test may also be helpful in these situations:
- Recurring yeast or Candida infections in the mouth or gut.
- Chronic skin rashes that do not respond to typical treatments.
- Long-term food sensitivities or unexplained digestive changes.
- Persistent mild respiratory issues, such as post-nasal drip or sinus pressure.
- People who have recently started a new stress management routine and want to see if it affects their immune markers.
This test can show if your immune system is working as expected in your saliva, which can help you and your doctor decide on next steps for managing symptoms or making changes. Delaying this test could mean missing early signs of immune changes that are easier to address when caught sooner.
Order this test to get a clear picture of your immune response in your saliva.
Preparing for Salivary Immune Marker Testing
Fasting is not required for this test, but it’s best to avoid eating, drinking, or brushing your teeth for at least 30 minutes before collecting your saliva sample. Always follow any specific instructions your doctor or healthcare provider gives you to make sure your sample is collected correctly and your results are as useful as possible.
Labs Included When Ordering Your Total Salivary, sIgA (Single Test)
| Test Name | Reference Range | What This Biomarker Means | Low and High Levels of Total Salivary, sIgA |
|---|---|---|---|
| Total Salivary, sIgA | 25 – 200 mg/dL | Total salivary sIgA is an antibody found in saliva that helps protect the mouth and digestive tract from bacteria, viruses, and other invaders. It is a key marker for mucosal immune function and can change with stress, infection, or inflammation. |
High levels mean your immune system may be responding to infection, inflammation, or allergies in the mouth or gut.
Low levels mean your immune defense in saliva may be reduced, which can happen with chronic stress, immune suppression, or long-term illness. |
Reference ranges may change slightly over time as labs update their standards and testing methods.
Total Salivary, sIgA FAQ
Is there Total Salivary, sIgA testing near me?
This is a home test kit, so you can collect your saliva sample wherever is most comfortable for you; check the draw location link at the top of the page for more details. For those dealing with ongoing immune or digestive issues, having a convenient collection option means you can get tested without extra travel or waiting, making it easier to track changes when symptoms arise.
How do I interpret the test results?
While your treating physician should review your results, we also offer a one-on-one test results review with our clinical team to help you understand what your numbers mean and what steps you might consider next.
What is the cost of the test?
The price you see for this test includes standard shipping to you and return shipping to the lab; draw fees may apply. Ordering this test can help you find out if your immune system is responding to stress or infection, which can help you get answers and support more quickly.
How often should I retest?
It is usually recommended to retest every 3 to 6 months, especially if you are monitoring changes in immune function or tracking how your body responds to new treatments or lifestyle changes. Regular testing can help you and your doctor see if your immune markers are improving or if further steps are needed.
How accurate is the test?
This test uses enzyme-linked immunosorbent assay (ELISA) to measure sIgA in saliva, with a specificity of 98% and sensitivity of 97%. TrueHealthLabs.com partners with CLIA-certified and CAP-certified laboratories to uphold rigorous testing standards for dependable results.
Important Notes
- This test can not be collected or mailed from New York State
Medical Review Board
Reviewed by Jeff Donohue M.D. from Body Logic and Brady Hurst DC, CCCN. Written by True Health Lab’s team of editorial health contributors.
Disclaimer: This information is for educational purposes only and not intended as medical advice. Consult your healthcare provider for personalized guidance.
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