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Lp-PLA2 Activity Test


  • Draw Locations
  • Turnaround Time: 2-4 Business Days on Average. Time may vary.
  • Not Available in: NY, NJ, MA, and RI
  • HSA and FSA Approved

$99.00 USD $405.00

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Ordering the Lp-PLA2 Activity Test

Ordering the Lp-PLA2 Activity Test (PLAC) can help assess the risk of cardiovascular conditions by measuring the activity of the Lp-PLA2 enzyme. Interestingly, this enzyme is linked to inflammation in the arteries, which can be a precursor to heart disease.

When you order this test, you can expect the following benefits:

  • Helps evaluate the risk of heart disease by measuring enzyme activity.
  • Provides insights into arterial inflammation levels.
  • Assists in monitoring the effectiveness of lifestyle changes or treatments.
  • Offers a clearer picture of cardiovascular health.
  • Supports informed decision-making with your healthcare provider.

Who Should Consider the PLAC Test

People with a family history of heart disease might find this test beneficial. For example, someone with a parent who had a heart attack at a young age may want to understand their own risk factors better.

Consider ordering this test if you:

  • Have a family history of cardiovascular issues.
  • Are experiencing unexplained fatigue or shortness of breath.
  • Have been diagnosed with high cholesterol or hypertension.
  • Are undergoing treatment for heart disease and need to monitor progress.
  • Have a history of inflammatory conditions, which can affect heart health.

Ordering this test can provide specific insights into your cardiovascular risk by measuring enzyme activity linked to arterial inflammation. Delaying this test might mean missing early signs of potential heart issues, which could be addressed with timely interventions.

High Lp-PLA2 can present a serious situation, so bring your test results to your treating physician.

lp-pla2 activity blood test chart showing inflammation in the arteries

How to Prepare for the Test

Fasting for 10-12 hours is preferred but not required for the Lp-PLA2 Test. It’s important to follow any instructions from your doctor or healthcare professional to ensure the test results are as informative as possible.

Labs Included When Ordering Your Lp-PLA2 Activity Test

Test Name Reference Range Significance Low and High Levels of Lp-PLA2 Activity
Lp-PLA2 Activity <123 Lp-PLA2 is an enzyme linked to inflammation in the arteries. High levels can indicate increased cardiovascular risk. High levels mean increased risk of heart disease due to arterial inflammation.

Low levels mean lower risk of cardiovascular issues.

Reference ranges may differ. Visit the Quest Diagnostics lab test directory for the latest values.


Lp-PLA2 Activity FAQ

Is there Lp-PLA2 Activity testing near me?

To find nearby locations for Lp-PLA2 Activity testing, use the patient service center locator, which includes mobile phlebotomy options. This is especially useful for those monitoring cardiovascular health who need convenient access to testing.

What is the cost of the test?

The cost of the test includes all fees, such as sample collection at patient service center locations. It’s worth ordering to assess cardiovascular risk factors, which can guide preventive measures.

How often should I retest?

Retesting every 6-12 months is recommended to monitor changes in enzyme activity, which can help track the effectiveness of any interventions or lifestyle changes.

How accurate is the test?

The Lp-PLA2 Activity Test uses enzyme-linked immunosorbent assay (ELISA) for precise measurement. TrueHealthLabs.com partners with CLIA-certified laboratories to uphold rigorous testing standards for dependable results.


Medical Review Board

Reviewed by Jeff Donohue M.D. from Body Logic and Brady Hurst DC, CCCN. Written by True Health Lab’s team of editorial health contributors.

Disclaimer: This information is for educational purposes only and not intended as medical advice. Consult your healthcare provider for personalized guidance.


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