Ordering the Lupus SLE Panel
Ordering the Lupus SLE Panel helps check for specific antibodies in the blood that are linked to autoimmune conditions like lupus. This test looks for antinuclear antibodies (ANA) and anti-double stranded DNA (dsDNA), which can help doctors find out if the immune system is attacking healthy cells. Interestingly, some people with lupus may have positive ANA results years before any symptoms appear, making early testing useful for those with a family history or mild symptoms.
When ordering the Lupus SLE Panel, you can expect several benefits:
- Detects antinuclear antibodies (ANA) that are often present in autoimmune conditions.
- Measures anti-double stranded DNA (dsDNA) antibodies, which are highly specific for lupus.
- Helps distinguish lupus from other autoimmune disorders with similar symptoms.
- Supports doctors in tracking changes in antibody levels over time for better treatment planning.
- Provides a clear starting point for further testing if results are positive or borderline.
Who Might Benefit from Lupus Antibody Screening
A person who has been feeling tired, experiencing joint pain, and noticing a butterfly-shaped rash on their face may wonder if these symptoms are connected. They might have a family member with lupus and want to know if their own symptoms could be related to an autoimmune condition.
Ordering this test may also be helpful in these situations:
- Someone with unexplained joint swelling and pain that does not improve with usual care.
- A person who has frequent low-grade fevers and hair loss without a clear cause.
- Someone who has had repeated episodes of skin rashes that get worse in sunlight.
- A person with a history of autoimmune conditions in their family who is starting to notice new symptoms.
- Someone who has been diagnosed with another autoimmune disorder and is now experiencing new symptoms that could overlap with lupus.
This test should be ordered to help identify the presence of specific antibodies that are linked to lupus, which can guide doctors in making a diagnosis and planning treatment. Delaying this test could mean missing early signs of lupus, which may lead to more severe symptoms before a diagnosis is made.
Preparing for Lupus Autoantibody Testing
Fasting is not required before this blood test, so you can eat and drink as usual. Always follow any instructions your doctor or healthcare provider gives you to make sure your sample is collected correctly and your results are as helpful as possible.
Labs Included When Ordering Your Lupus SLE Panel
| Test Name | Reference Range | What This Test Measures | Low and High Levels of Lupus SLE Panel |
|---|---|---|---|
| Antinuclear Antibodies (ANA) | Negative: <1:40 | ANA testing checks for antibodies that target the cell nucleus, which are often found in people with autoimmune conditions. A positive result can suggest lupus or other autoimmune diseases. |
High levels mean the immune system may be attacking healthy cells, which is common in lupus and other autoimmune disorders.
Low levels mean it is less likely that an autoimmune process like lupus is present. |
| Anti-Double Stranded DNA (dsDNA) | Negative: <10 IU/mL | This test looks for antibodies against double-stranded DNA, which are highly specific for lupus. High levels are rarely seen in other conditions, making this test important for confirming lupus. |
High levels mean there is a strong chance of lupus, especially if symptoms match.
Low levels mean lupus is less likely, but other autoimmune conditions may still be possible. |
Reference ranges can change over time. For the most current values, visit the Quest Diagnostics lab test directory.
Lupus SLE Panel FAQ
Is there Lupus SLE Panel testing near me?
You can find a nearby location for Lupus SLE Panel testing using the patient service center locator, which also lists mobile phlebotomy options for added convenience. For those experiencing ongoing joint pain or fatigue, having a close and accessible testing site makes it easier to get blood drawn without extra travel or stress.
What is the cost of the test?
The price for the Lupus SLE Panel includes all fees, such as sample collection at patient service center locations. Ordering this test can help clarify the cause of symptoms like unexplained rashes or joint pain, making it a practical step for those seeking answers.
How often should I retest?
Retesting is usually recommended if symptoms change, new symptoms appear, or as advised by your doctor, especially if you have a known autoimmune condition. Regular retesting helps track changes in antibody levels, which can guide treatment adjustments and monitor disease activity.
How accurate is the test?
The Lupus SLE Panel uses immunofluorescence for ANA and ELISA for dsDNA, both of which are well-established laboratory methods. The ANA test has a sensitivity of about 95% and a specificity of 57%, while the dsDNA test has a specificity of 97% and a sensitivity of 70%. All tests at TrueHealthLabs.com are performed by CLIA-certified labs, meeting strict quality and precision standards.
Medical Review Board
Reviewed by Jeff Donohue M.D. from Body Logic and Brady Hurst DC, CCCN. Written by True Health Lab’s team of editorial health contributors.
Disclaimer: This information is for educational purposes only and not intended as medical advice. Consult your healthcare provider for personalized guidance.
Why Customers Trust True Health Labs – What People are saying
Also rated 4.6 out of 5 based on 3452 ShopperApproved reviews- See all TrueHealthLabs.com reviews.
