Ordering the Hormones Comprehensive Panel by Great Plains Labs
Ordering the Hormones Comprehensive Panel by Great Plains Labs helps identify hormone imbalances that may be linked to symptoms like fatigue, mood changes, hair loss, or irregular periods. This test measures estrogen, progesterone, testosterone, DHEA, and cortisol at four points during the day, providing a detailed look at hormone patterns. Interestingly, testing cortisol at multiple times throughout the day can reveal hidden stress patterns that a single morning sample might miss.
When ordering this panel, you gain specific benefits:
- Detects hormone imbalances that may contribute to symptoms such as weight gain, low libido, or sleep problems
- Monitors hormone levels for those using hormone therapy or supplements
- Assesses adrenal function by measuring cortisol at four different times
- Supports fertility planning by tracking estrogen and progesterone
- Helps guide treatment for conditions like PCOS, menopause, or thyroid issues
Who Should Consider Comprehensive Hormone Testing
People who have been feeling tired for weeks, struggling with mood swings, or noticing changes in their hair or skin may benefit from this test. For example, someone who has tried different diets and exercise routines but still experiences stubborn weight gain and low energy could use this test to check for hormone imbalances that might be affecting their progress.
Ordering this test may also be helpful in these situations:
- Experiencing irregular menstrual cycles or skipped periods
- Dealing with ongoing sleep problems or waking up feeling unrested
- Facing unexplained hair thinning or loss
- Managing symptoms of menopause, such as hot flashes or night sweats
- Noticing changes in skin texture or persistent adult acne, which can sometimes be linked to hormone shifts
Testing for hormone levels can help pinpoint the cause of symptoms like fatigue, mood changes, or changes in body composition, making it easier to choose the right treatment or lifestyle changes. Delaying this test could mean missing the chance to address hormone imbalances early, which may allow symptoms to continue or worsen over time.
Preparing for a Hormone and Adrenal Panel
Fasting is not required for this saliva-based test, but it’s important to collect samples at the specific times listed in the kit instructions. Always follow the directions provided by your doctor or healthcare professional to make sure your samples are collected correctly and your results are as useful as possible.
Labs Included When Ordering Your Hormones Comprehensive Panel by Great Plains Labs
| Test Name | Reference Range | What the Test Measures | Low and High Levels of the Marker |
|---|---|---|---|
| Estradiol (Estrogen) | Women (premenopausal): 1.3–3.3 pg/mL Women (postmenopausal): 0.5–1.0 pg/mL Men: 0.5–1.2 pg/mL |
Estradiol is the main form of estrogen in the body. It helps control menstrual cycles, bone strength, and mood. This test checks for hormone balance and can help explain symptoms like irregular periods or hot flashes. |
High levels mean there may be estrogen dominance, which can cause symptoms like heavy periods, weight gain, or breast tenderness.
Low levels mean there may be a risk for bone loss, mood changes, or symptoms like hot flashes and night sweats. |
| Progesterone | Luteal phase: 75–270 pg/mL Follicular phase: 12–100 pg/mL Postmenopausal: 5–50 pg/mL |
Progesterone helps prepare the body for pregnancy and balances the effects of estrogen. This test can help explain symptoms like irregular cycles, PMS, or fertility problems. |
High levels mean there may be ovarian cysts or hormone therapy effects.
Low levels mean there may be trouble with ovulation, increased PMS, or risk for miscarriage. |
| Testosterone | Men: 30–120 pg/mL Women: 10–45 pg/mL |
Testosterone supports muscle strength, energy, and sex drive in both men and women. This test can help explain low energy, reduced muscle mass, or changes in libido. |
High levels mean there may be PCOS in women or risk for acne and hair loss.
Low levels mean there may be fatigue, low sex drive, or decreased muscle strength. |
| DHEA | Men: 150–500 pg/mL Women: 100–350 pg/mL |
DHEA is a hormone made by the adrenal glands. It helps make other hormones and supports energy, mood, and immune function. This test can help explain fatigue or changes in stress response. |
High levels mean there may be adrenal overactivity or hormone supplementation.
Low levels mean there may be adrenal fatigue, low energy, or reduced stress tolerance. |
| Cortisol (4x a day) |
Morning: 3.7–9.5 ng/mL Noon: 1.2–3.0 ng/mL Evening: 0.6–1.9 ng/mL Night: 0.4–1.0 ng/mL |
Cortisol is the main stress hormone. Testing it at four times during the day shows how your body responds to stress and helps explain symptoms like fatigue, sleep problems, or anxiety. |
High levels mean there may be ongoing stress, sleep problems, or adrenal overactivity.
Low levels mean there may be adrenal fatigue, low energy, or trouble handling stress. |
Reference ranges may change slightly as labs update their standards, so always check your report for the most current values.
Hormones Comprehensive Panel by Great Plains Labs FAQ
Is there Hormones Comprehensive Panel by Great Plains Labs testing near me?
This is a home test kit that you can collect locally, and you can check the draw location link at the top of the page for more details. For people dealing with symptoms like fatigue or mood swings, having a convenient collection option means you can get tested quickly and easily without extra travel or waiting.
How do I interpret the test results?
While your treating physician should review your results, we also offer a one-on-one test results review with our clinical team to help you understand your hormone levels and what they mean for your symptoms.
What is the cost of the test?
The price listed for this test includes standard shipping to you and return shipping to the lab, but draw fees may apply. Ordering this test can help you find out if hormone imbalances are causing symptoms like fatigue or weight gain, so you can start working on solutions sooner.
How often should I retest?
It’s best to retest every 3 to 6 months, especially if you are starting or changing hormone therapy, or if your symptoms change. Regular testing helps track your progress and makes it easier to adjust your treatment plan as needed.
How accurate is the test?
This test uses saliva samples analyzed by enzyme immunoassay, which is known for its high sensitivity (95%) and specificity (92%) for hormone detection. TrueHealthLabs.com partners with CLIA-certified and CAP-certified laboratories to uphold rigorous testing standards for dependable results.
Important Notes
- This test can not be collected or mailed from New York State. Contact us with questions.
Medical Review Board
Reviewed by Jeff Donohue M.D. from Body Logic and Brady Hurst DC, CCCN. Written by True Health Lab’s team of editorial health contributors.
Disclaimer: This information is for educational purposes only and not intended as medical advice. Consult your healthcare provider for personalized guidance.
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