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Comprehensive Melatonin Profile | Canada


  • Home Test Kit
  • Processed by Genova Diagnostics Diagnostics
  • Turnaround Time: 5-8 Business Days on Average. Time may vary.
  • HSA and FSA Approved

$279.00 USD $558.00

100% interest free financing + no late fees
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Ordering the Comprehensive Melatonin Profile | Canada

The Comprehensive Melatonin Profile helps measure melatonin levels at different times to show how your body’s sleep-wake cycle is working. This test is useful for people who have trouble falling asleep, staying asleep, or waking up too early. Interestingly, melatonin is not only important for sleep but also plays a role in regulating body temperature and supporting immune function.

Ordering this test can help you:

  • Identify if your melatonin production is too low or too high at certain times of day or night
  • Pinpoint possible causes of sleep disruption, such as shift work or irregular sleep schedules
  • Track how well your body is adjusting to changes in daylight or travel across time zones
  • Monitor the effects of sleep aids or supplements on your natural melatonin rhythm
  • Support your healthcare provider in making decisions about sleep therapy or lifestyle changes

Who Should Consider Melatonin Rhythm Testing

A person who wakes up feeling tired even after a full night’s rest, or who struggles to fall asleep at a regular time, may benefit from this test. For example, someone who works late shifts and finds it hard to adjust their sleep schedule could use this test to see if their melatonin levels are out of sync.

Ordering this test may also be helpful in these situations:

  • Difficulty falling asleep or staying asleep for several weeks
  • Frequent travel across time zones causing sleep disruption
  • Children or teens with delayed sleep phase patterns
  • Adults using sleep supplements who want to check their natural melatonin production
  • People with chronic headaches, as melatonin imbalances can sometimes be linked to migraine patterns

Testing can show if your body is making melatonin at the right times, which can help you and your healthcare provider make changes that improve your sleep cycle. Delaying this test may mean missing the chance to find and fix a sleep pattern problem before it becomes harder to manage.

Preparing for Sleep Cycle Hormone Testing

Fasting is not required for this test, but you should follow the specific instructions included in your test kit for the best results. Always go by any directions your doctor or healthcare professional gives you to make sure your sample is collected correctly and your results are useful.

Labs Included When Ordering Your Comprehensive Melatonin Profile

Test Name Reference Range What This Measures Low and High Levels of Melatonin
Melatonin (Saliva, Multiple Time Points) Night (2-4 a.m.): 10-80
Morning (6-8 a.m.): 1-5
Afternoon (12-2 p.m.): 1-3
Evening (10 p.m.-midnight): 5-15
Melatonin is a hormone that helps control your sleep and wake cycle. This test checks how much melatonin your body makes at different times of the day and night. High levels mean your body may be making too much melatonin, which can cause daytime sleepiness or trouble waking up.

Low levels mean your body may not be making enough melatonin, which can lead to trouble falling asleep or staying asleep.

Reference ranges may change slightly as labs update their methods or as new research becomes available.


Comprehensive Melatonin Profile FAQ

Is there Comprehensive Melatonin Profile testing near me?

This is a home test kit that you can collect yourself, and you can check the draw location link at the top of the page for more details. For those struggling with sleep issues, being able to collect your sample at home makes it easier to test at the right time without extra travel or stress.

How do I interpret the test results?

While your treating physician should help you understand your results, we also offer a one-on-one test results review with our clinical team to help you make sense of your numbers and what they mean for your sleep cycle.

What is the cost of the test?

The price you see for this test includes standard shipping to you and return shipping back to the lab, but draw fees may apply. Ordering this test can help you find out if your melatonin levels are affecting your sleep, so you can start making changes sooner.

How often should I retest?

It’s best to retest every 3 to 6 months, especially if you are making changes to your sleep routine or using supplements, so you can track how your melatonin levels respond over time.

How accurate is the test?

This test uses a saliva sample analyzed by enzyme-linked immunosorbent assay (ELISA), which has a specificity of 98% and a sensitivity of 97%. TrueHealthLabs.com partners with CLIA-certified and CAP-certified laboratories to uphold rigorous testing standards for dependable results.


Medical Review Board

Reviewed by Jeff Donohue M.D. from Body Logic and Brady Hurst DC, CCCN. Written by True Health Lab’s team of editorial health contributors.

Disclaimer: This information is for educational purposes only and not intended as medical advice. Consult your healthcare provider for personalized guidance.


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