Ordering the Comprehensive Male Profile 1 | ZRT Labs
The Comprehensive Male Profile 1 from ZRT Labs is designed to measure key hormones and markers that affect energy, mood, muscle mass, metabolism, and prostate function. This test uses both saliva and blood spot samples, making it convenient for at-home collection and providing a broad view of hormone balance, thyroid function, and prostate health. Interestingly, this test measures cortisol at four different times throughout the day, which can reveal patterns of stress response that a single measurement might miss.
Ordering this test can help you:
- Track testosterone, estradiol, and DHEAS levels to assess hormone balance and its impact on muscle strength, mood, and libido.
- Monitor cortisol at four points in the day to identify stress patterns that may affect sleep, energy, and weight.
- Check thyroid markers (TSH, Free T3, Free T4, TPO, and Anti-TG Antibodies) to detect thyroid issues that can cause fatigue, weight changes, and hair loss.
- Screen for prostate-specific antigen (PSA) to help detect early changes in prostate health.
- Identify inflammation or autoimmune activity with Hashimoto’s screening markers.
Who Should Consider Hormone and Thyroid Panel Testing
People who notice changes in energy, mood, or physical performance may benefit from this test. For example, someone who has been feeling more tired than usual, has noticed a drop in muscle mass, or is experiencing changes in sleep or mood may find this test helpful in pinpointing the cause.
Ordering this test may also be useful in these situations:
- Experiencing unexplained weight gain or difficulty losing weight despite regular exercise and healthy eating.
- Dealing with low libido or changes in sexual function that are not explained by other factors.
- Noticing increased hair loss or thinning hair over several months.
- Having a family history of thyroid or prostate issues and wanting to monitor these markers proactively.
- Feeling unusually anxious or irritable in the late afternoon, which can be linked to cortisol fluctuations.
Testing these markers can help identify hormone or thyroid imbalances that may be affecting energy, mood, and physical performance. Delaying this test could mean missing early signs of hormone or thyroid changes, which may make it harder to address symptoms quickly and effectively. To move forward, consider ordering the test to get a clearer picture of your hormone and thyroid status.
Preparing for At-Home Hormone and Thyroid Testing
Fasting is not required for this test, so you can collect your saliva and blood spot samples at any time as directed. Always follow the specific instructions provided by your doctor or healthcare practitioner to ensure your samples are collected correctly and your results are as useful as possible.
Labs Included When Ordering Your Comprehensive Male Profile 1
| Test Name | Reference Range | What This Marker Means | Low and High Levels of This Marker |
|---|---|---|---|
| Saliva Markers | |||
| Testosterone | 70–205 pg/mL | This hormone supports muscle mass, bone strength, mood, and sexual function. It is a key marker for male hormone balance and vitality. |
High levels mean possible increased risk for acne, irritability, or prostate issues.
Low levels mean possible fatigue, low libido, reduced muscle mass, or mood changes. |
| Estradiol (E2) | 0.5–3.3 pg/mL | Estradiol is a form of estrogen that helps regulate bone density, mood, and cholesterol. It is important for men’s metabolic and cardiovascular function. |
High levels mean possible increased risk for gynecomastia, weight gain, or mood swings.
Low levels mean possible bone loss or joint discomfort. |
| Cortisol (Morning, Noon, Evening, Midnight) |
Morning: 3.7–9.5 ng/mL Noon: 1.2–3.0 ng/mL Evening: 0.6–1.9 ng/mL Midnight: 0.4–1.0 ng/mL |
Cortisol is a stress hormone that follows a daily rhythm. Measuring it at four times shows how your body responds to stress and regulates sleep, energy, and metabolism. |
High levels mean possible ongoing stress, sleep problems, or weight gain.
Low levels mean possible fatigue, low blood pressure, or trouble handling stress. |
| DHEAS | 80–560 pg/mL | DHEAS is a hormone made by the adrenal glands that helps produce other hormones, including testosterone and estrogen. It supports energy, mood, and immune function. |
High levels mean possible increased risk for acne, hair loss, or irritability.
Low levels mean possible fatigue, low mood, or reduced muscle strength. |
| Blood Spot Markers | |||
| Prostate-specific Antigen (PSA) | 0–4 ng/mL | PSA is a protein made by the prostate gland. It is used to screen for changes in prostate health and can help detect early signs of prostate problems. |
High levels mean possible prostate inflammation, enlargement, or other prostate changes.
Low levels mean normal prostate function. |
| TSH | 0.5–3.0 μIU/mL | TSH is a hormone that tells the thyroid gland how much thyroid hormone to make. It is a key marker for thyroid function and metabolism. |
High levels mean possible underactive thyroid (hypothyroidism).
Low levels mean possible overactive thyroid (hyperthyroidism). |
| Free T3 | 2.3–4.2 pg/mL | Free T3 is the active form of thyroid hormone that helps control energy, temperature, and metabolism. It is important for how your body uses energy. |
High levels mean possible overactive thyroid, anxiety, or rapid heartbeat.
Low levels mean possible underactive thyroid, fatigue, or weight gain. |
| Free T4 | 0.8–1.8 ng/dL | Free T4 is a thyroid hormone that helps regulate metabolism and energy. It works with TSH and Free T3 to keep your body’s systems running smoothly. |
High levels mean possible overactive thyroid or thyroid hormone therapy.
Low levels mean possible underactive thyroid or thyroid gland issues. |
| TPO and Anti-TG Antibodies (Hashimoto’s Screen) | TPO: <35 IU/mL Anti-TG: <40 IU/mL |
These antibodies can show if the immune system is attacking the thyroid, which can lead to thyroid problems like Hashimoto’s disease. They help detect autoimmune thyroid issues early. |
High levels mean possible autoimmune thyroid disease or inflammation.
Low levels mean no sign of thyroid autoimmunity. |
Reference ranges may change slightly as labs update their standards, so always check your report for the most current values.
Comprehensive Male Profile 1 FAQ
Is there Comprehensive Male Profile 1 testing near me?
This is an at-home test kit, so you can collect your saliva and blood spot samples wherever is most comfortable for you; check the draw location link at the top of the page for more details. For those experiencing symptoms like fatigue or hormone changes, having a convenient collection option means you can get tested quickly without waiting for a clinic appointment.
How do I interpret the test results?
While your treating physician should review your results, we also offer a one-on-one test results review with our clinical team to help you understand your results and next steps.
What is the cost of the test?
The price listed for this test includes standard shipping to you and return shipping to the lab, though draw fees may apply. Ordering this test can help you address hormone or thyroid imbalances sooner, which may help you feel better faster.
How often should I retest?
It is recommended to retest every 6 to 12 months, or as advised by your healthcare provider, to track changes in hormone and thyroid markers over time. Regular testing helps you and your provider adjust your plan if your levels shift.
How accurate is the test?
This test uses saliva and blood spot collection, analyzed by liquid chromatography-tandem mass spectrometry (LC-MS/MS) and immunoassay methods, with specificity and sensitivity both above 95%. TrueHealthLabs.com partners with CLIA-certified and CAP-certified laboratories to uphold rigorous testing standards for dependable results.
Important Notes
- The blood samples cannot be collected and mailed in the state of New York.
Medical Review Board
Reviewed by Jeff Donohue M.D. from Body Logic and Brady Hurst DC, CCCN. Written by True Health Lab’s team of editorial health contributors.
Disclaimer: This information is for educational purposes only and not intended as medical advice. Consult your healthcare provider for personalized guidance.
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