Ordering the Coronavirus COVID-19 Vaccine Response Test Panel
Ordering the Coronavirus COVID-19 Vaccine Response Test Panel helps you check if your body is making antibodies and T-cells after getting the COVID-19 vaccine. This test can show if your immune system is responding well to the vaccine or if you might need another dose. Interestingly, some people may have a strong T-cell response even if their antibody levels are low, which can still provide protection.
When ordering this test, you can expect these specific benefits:
- Shows if your body is making SARS-CoV-2 antibodies (IgM and IgG) after vaccination.
- Checks if your T-cells are activated, which can mean longer-lasting protection.
- Helps decide if you may need another vaccine dose for better protection.
- Reveals if you have natural immunity from a past infection.
- Gives clear results to share with your doctor for next steps.
Who Should Consider Immune Response Testing After COVID-19 Vaccination
People who want to know if their body is responding to the COVID-19 vaccine, like someone who has a weakened immune system and is unsure if the vaccine worked, would benefit from this test. For example, a person who has had several vaccine doses but still feels worried about their protection can use this test to see if their immune system is making antibodies or T-cells.
Ordering this test may also be helpful in these situations:
- Someone who has had COVID-19 before and wants to know if they have natural immunity.
- A person who is planning to travel and needs proof of immune response for entry requirements.
- Anyone who is part of a high-risk group, like healthcare workers, and wants to check their protection.
- People who have experienced side effects after vaccination and want to see if their immune system responded.
- Someone who has a family member with a weak immune system and wants to make sure they are not at risk of spreading the virus, which is not always considered but can be important for household safety.
This test gives you clear answers about your immune response, so you can make informed decisions about your next steps. Delaying this test could mean missing the chance to catch a weak response early, which might affect your protection against COVID-19.
Preparing for Immune System Response Testing
Fasting is not required for this test, so you can eat and drink as usual before your blood draw. Always follow any instructions your doctor or healthcare provider gives you to make sure your sample is collected and shipped correctly.
Labs Included When Ordering Your Coronavirus COVID-19 Vaccine Response Test Panel
| Test Name | Reference Range | What This Test Measures | Low and High Levels of This Test |
|---|---|---|---|
| SARS-CoV-2 ImmunoBlot IgM Antibody | Negative | This test checks for IgM antibodies, which are the first type of antibody your body makes after exposure to the coronavirus or after vaccination. IgM antibodies usually appear early and can show a recent response to the virus or vaccine. |
High levels mean your body is having a recent or active response to the virus or vaccine.
Low levels mean there is no recent or active response, or it is too early or too late to detect IgM. |
| SARS-CoV-2 ImmunoBlot IgG Antibody | Negative | This test looks for IgG antibodies, which usually develop later and can show longer-term immune response after infection or vaccination. IgG antibodies can indicate if you have developed lasting protection. |
High levels mean your body has developed a longer-term immune response, likely from vaccination or past infection.
Low levels mean you may not have developed lasting antibodies, or it is too soon after exposure or vaccination. |
| SARS-CoV-2 IgXSpot T-cell Response | Negative | This test measures if your T-cells are activated against the coronavirus, which can provide protection even if antibody levels are low. T-cells help your body remember and fight the virus in the future. |
High levels mean your T-cells are active and may give you longer-lasting protection, even if antibodies are low.
Low levels mean your T-cells are not showing a strong response, which could mean less protection. |
Reference ranges may change slightly as labs update their methods and guidelines.
Coronavirus COVID-19 Vaccine Response Test Panel FAQ
Is there Coronavirus COVID-19 Vaccine Response Test Panel testing near me?
This is a test kit that you can collect at a local blood draw site or clinic; check the draw location link at the top of the page. For people who need to monitor their immune response after vaccination, having a nearby collection site makes it easier to get tested quickly and without extra travel.
How do I interpret the test results?
While your treating physician should help you understand your results, we also offer a one-on-one test results review with our clinical team to help you make sense of your immune response.
What is the cost of the test?
The price you see for the test includes standard shipping to you and back to the lab, but some blood draw sites may charge a separate fee. Ordering this test is worth it because it can help you find out if your body is responding to the vaccine, which can help you and your doctor make faster decisions about your care.
How often should I retest?
It is usually recommended to retest about 4-6 weeks after your last vaccine dose or if you have a change in your health status. Retesting can help you see if your immune response has changed over time, especially if you are at higher risk or have ongoing concerns.
How accurate is the test?
This test uses ImmunoBlot antibody testing and the IgXSpot T-cell method, which are advanced techniques for detecting immune response. The ImmunoBlot has a specificity of 98% and a sensitivity of 97%. TrueHealthLabs.com partners with CLIA-certified and CAP-certified laboratories to uphold rigorous testing standards for dependable results.
Important Notes
- Disclaimer: Test results are not a substitute for medical advice. Any information given here or elsewhere on TrueHealthLabs.com is for educational purposes only and has not been evaluated by the FDA. Samples are collected at your own risk. As with any lab test, false negatives/positives can occur. Consult with your treating physician to determine if re-testing is needed and for further examination and treatment.
- Results should be used in conjunction with advice from your doctor since a positive result do not guarantee immunity.
- Keep blood vials at room temperature. Do not allow refrigeration.
- The specimen must arrive at the lab within 2 days (2-day shipping label is included with the kit).
- Test results will be reported to your state’s health department.
Medical Review Board
Reviewed by Jeff Donohue M.D. from Body Logic and Brady Hurst DC, CCCN. Written by True Health Lab’s team of editorial health contributors.
Disclaimer: This information is for educational purposes only and not intended as medical advice. Consult your healthcare provider for personalized guidance.
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