Phosphorylated Tau 217 Test (pTau-217)

Ordering the Phosphorylated Tau 217 Test (pTau-217)

The Phosphorylated Tau 217 Test (pTau-217) helps measure a specific protein in the blood that is linked to changes in the brain, especially those seen in memory and thinking problems. This test is often used to support early detection of brain changes related to memory loss, confusion, and cognitive decline. Interestingly, research shows that pTau-217 levels can rise years before symptoms of memory loss appear, making it a useful tool for tracking early changes in the brain.

Ordering this test can help you and your healthcare provider:

• Detect early signs of brain changes linked to memory and thinking problems
• Monitor the progression of cognitive decline over time
• Support decisions about further brain imaging or other tests
• Track the effects of treatment or lifestyle changes on brain health
• Provide a clearer picture of possible causes of memory issues

Who Should Consider Brain Protein Marker Testing

People who notice they are forgetting things more often, struggling to find words, or feeling confused in familiar situations may benefit from this test. For example, someone who has started to misplace important items or repeat questions during conversations might want to check for changes in brain proteins that could explain these symptoms.

Ordering this test may also be helpful in these situations:

• Family history of memory loss or dementia
• Unexplained changes in thinking or focus
• Difficulty with daily tasks that were once easy
• Monitoring brain health after a head injury
• Tracking changes in people with sleep disorders, as disrupted sleep can affect brain proteins

Testing for this protein can help identify changes in the brain that may not be seen with other tests, allowing for earlier and more targeted support. Delaying this test could mean missing the chance to spot early changes that are easier to track and manage when found sooner.

Preparing for Memory and Cognitive Marker Lab Work

Fasting is not required before this blood test, so you can eat and drink as usual unless your doctor gives you other instructions. Always follow any directions from your healthcare provider to make sure your sample is collected and processed correctly.

Labs Included When Ordering Your Phosphorylated Tau 217 Test (pTau-217)

Reference ranges may change slightly as labs update their methods and research advances.

Phosphorylated Tau 217 Test FAQ

Is there Phosphorylated Tau 217 testing near me?

This test is provided as a kit that can be collected at a local draw site—check the draw location link at the top of the page. For people experiencing memory changes or confusion, having a nearby collection site makes it easier to get tested without added stress or travel.

How do I interpret the test results?

While your treating physician should review your results, you can also use our one-on-one test results review service with our clinical team for a detailed explanation and next steps.

What is the cost of the test?

The price listed for this test includes standard shipping to you and return shipping to the lab, though draw fees may apply. Ordering this test can help you find out if changes in brain proteins are linked to your memory or thinking problems, which can help you get answers sooner.

How often should I retest?

Retesting is usually recommended every 6 to 12 months if you are tracking changes in memory or cognitive function, or as advised by your healthcare provider. Regular testing helps monitor changes over time and supports timely decisions about care or treatment.

How accurate is the test?

This test uses a highly sensitive immunoassay method to measure p-tau217 in plasma, with a specificity of 96% and sensitivity of 92%. TrueHealthLabs.com partners with CLIA-certified and CAP-certified laboratories to uphold rigorous testing standards for dependable results.

Important Notes

• This test is not available in New York. Contact us with questions.