Tickborne BBB Plus 1 day by Mosaic Diagnostics (formerly Great Plains Labs) is a blood and serum panel for active tick-borne and flea-borne infections. If you want clearer next steps for ongoing fatigue, headaches, joint pain, or stubborn “Lyme-like” symptoms, this panel combines direct DNA detection with a Bartonella antibody check.
Ordering The Tickborne BBB Plus 1 Day
Tickborne BBB Plus 1 day uses one whole-blood draw plus one serum draw. The DNA portion uses digital PCR (dPCR), which splits the sample into many tiny parts to help detect very low levels of Bartonella, Babesia, or Borrelia DNA.
Bartonella can be hard to catch because it may circulate in very small amounts and can live inside cells. Tickborne BBB Plus 1 day adds a culture enrichment step (Culture dPCR) to improve the chance of detection before the DNA readout.
What many people like about ordering Tickborne BBB Plus 1 day:
- DNA plus antibody coverage: looks for DNA signals and a Bartonella IgG immune response.
- One visit collection: designed as a practical starting point without multiple draw days.
- Broad genus coverage: screens across Bartonella, Babesia, and Borrelia groups.
- Decision support: helps your clinician prioritize next steps when symptoms overlap.
Why This Test Is Important To Order
Tickborne BBB Plus 1 day pairs direct DNA detection with Bartonella IgG antibody testing. This matters because antibody-only testing can miss cases where the immune response is weak or delayed.
The Borrelia DNA component can also help when symptoms overlap across conditions like brain fog, nerve sensations, sleep issues, and migrating aches. Thinking in simple terms, antibodies can reflect exposure, while DNA detection can support what is happening now.
Why Someone Should Consider Ordering This Test
Tickborne BBB Plus 1 day is a fit when symptoms feel persistent and hard to explain. Consider ordering if you have ongoing fatigue, headaches, swollen glands, mood or sleep changes, joint or muscle pain, or unusual nerve symptoms with possible tick or flea exposure.
It can also help when you are weighing co-infections that need different treatment plans. Babesia patterns can include sweats and shortness of breath, while Bartonella patterns can include nerve pain and stubborn whole-body symptoms, so results can help focus the conversation with your clinician.
If your clinician suspects symptoms come in waves, a multi-day draw approach for a related profile may be discussed. Many people start with ordering Tickborne BBB Plus 1 day for a fast baseline, then decide next steps based on results and how they feel.
Labs Included When Ordering
| Test | What It Helps With (Plain Language) |
|---|---|
| Babesia spp. | Looks for Babesia DNA in blood, which can support a current infection. This can matter when sweats, shortness of breath, or deep fatigue are hard to explain. |
| Bartonella spp. | Looks for Bartonella DNA in blood using dPCR, designed to detect very small amounts. This can help when symptoms fit but standard testing is negative. |
| Borrelia spp. dPCR | Looks for Borrelia DNA in blood at the genus level. This can support a tick-borne picture when symptoms overlap and co-infections are possible. |
| Bartonella spp. Culture dPCR | Uses a culture enrichment step before DNA detection to increase detectability. This can help when Bartonella is present at very low levels. |
Tickborne BBB Plus 1 Day FAQ
Is there Tickborne BBB Plus 1-day testing near me?
In most areas, you can complete the collection through convenient draw sites. Use these draw centers to find a location that fits your schedule, which helps when symptoms make travel or long waits difficult.
What is the cost of the test?
The price is listed at the top of the page. Shipping is included.
Can you help me interpret my test results?
Results should be reviewed with your treating clinician, and any support here is educational only, not medical advice. If you want help understanding what your report may mean for next steps, you can use the One-On-One Results Review.
How often should I retest?
Many clinicians consider retesting about 6 to 8 weeks after a meaningful treatment change or if symptoms return. This timing helps you compare results more fairly and avoid confusing “too-soon” changes.
How accurate is the test?
Tickborne BBB Plus 1 day uses dPCR to look for DNA and IFA to measure Bartonella IgG antibodies. Like all infectious disease testing, accuracy depends on timing, sample type, and whether the organism is circulating at the time of collection, and the testing is performed in a CLIA-certified lab.
What does 1 day mean for my order?
It means collection is designed to be completed in a single visit for whole blood plus serum. If symptoms seem to come in waves, you may consider a multi-day approach using a related profile.
If my result is negative, does that rule it out?
No, a negative result does not fully rule out these infections. If symptoms and exposure history still fit, talk with your clinician about timing, prior antibiotics, and whether a different strategy makes sense.
Medical Review Board
Reviewed by Jeff Donohue M.D. from Body Logic and Brady Hurst DC, CCCN. Written by True Health Lab’s team of editorial health contributors.
Disclaimer: This information is for educational purposes only and not intended as medical advice. Consult your healthcare provider for personalized guidance.
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