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Pregnenolone LC/MS/MS Test


  • The Pregnenolone lab test measures pregnenolone levels to help assess hormone balance affecting energy, stress, and mood.
  • Draw Locations
  • Turnaround Time: 2-4 Business Days on Average. Time may vary.
  • Availability: Allowed if address and testing are outside NY, NJ, MA, RI
  • HSA and FSA Approved

$139.00 USD $285.00

✅ 100% interest free financing + no late fees
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Ordering the Pregnenolone LC/MS/MS Test

Pregnenolone is a precursor hormone that plays a significant role in the production of other hormones like cortisol, estrogen, and testosterone. Monitoring its levels can provide valuable insights into hormonal imbalances. Interestingly, pregnenolone levels can influence memory and cognitive function, making this test relevant for those experiencing memory issues.

Understanding the benefits of this test can help you make informed decisions:

  • Identifies hormonal imbalances that may affect mood and energy levels.
  • Assists in evaluating adrenal gland function.
  • Supports the diagnosis of conditions related to hormone production.
  • Helps in monitoring the effectiveness of hormone replacement therapy.
  • Provides insights into potential causes of fatigue and stress.

Who Should Consider the Hormone Precursor Test

Individuals experiencing unexplained fatigue, mood swings, or changes in memory might find this test beneficial. For example, a person noticing a decline in their ability to concentrate at work may consider this test to explore potential hormonal causes.

Here are other scenarios where this test might be relevant:

  • Experiencing persistent fatigue despite adequate rest.
  • Undergoing hormone replacement therapy and needing to monitor its effects.
  • Dealing with unexplained mood changes or irritability.
  • Having a family history of hormonal disorders.
  • Experiencing changes in skin texture or hair growth.

Testing can help identify hormonal imbalances that might be affecting your daily life. Delaying the test could mean prolonged discomfort or symptoms that might be managed with appropriate interventions.

Preparing for Your Hormone Level Assessment

Fasting is not required for this test. It’s important to adhere to your doctor’s guidance regarding any medications or supplements you are taking.

Labs Included When Ordering Your Pregnenolone LC/MS/MS Test

Test Name Reference Range Significance Low and High Levels of Pregnenolone LC/MS/MS
Pregnenolone, LC/MS/MS < 151 Pregnenolone is a precursor to many hormones, including cortisol and testosterone. It plays a role in stress response and energy levels. High levels mean potential adrenal hyperactivity or hormone therapy effects.

Low levels mean possible adrenal insufficiency or hormonal imbalance.

Reference ranges can vary. Check the Quest Diagnostics lab test directory for updated ranges.


Pregnenolone LC/MS/MS FAQ

Is there Pregnenolone LC/MS/MS testing near me?

Using our patient service center locator, you can find nearby locations for your test, including mobile phlebotomy options. During the sample collection, a skilled technician will guide you through the process, ensuring a smooth and comfortable experience.

What is the cost of the test?

The cost of the Calcitonin Test is listed above. Pricing includes collection fees at patient service centers, ensuring transparency with no hidden costs.

How often should I retest?

Retesting is generally recommended every 6 to 12 months, especially if you are undergoing hormone therapy or experiencing symptoms. Regular monitoring helps in adjusting treatment plans effectively.

How accurate is the test?

The test uses Liquid Chromatography-Tandem Mass Spectrometry (LC/MS/MS) for precise measurement of pregnenolone levels. TrueHealthLabs.com partners with CLIA-certified labs, ensuring high standards of testing accuracy and reliability.


Medical Review Board

Reviewed by Jeff Donohue M.D. from Body Logic and Brady Hurst DC, CCCN. Written by True Health Lab’s team of editorial health contributors.

Disclaimer: This information is for educational purposes only and not intended as medical advice. Consult your healthcare provider for personalized guidance.


Why Customers Trust True Health Labs – What People are saying

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Joseph
October 30, 2026
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Quick and reliable. Customer service team was very helpful in test selection process. Easy to communicate with.

Owner's reply
Thanks Joseph for the kind words. We love our customer service department. Amazing team. Even though you had a great experience, we would love any feedback you can give. [email protected]
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Tyler H
August 24, 2026
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Peter is very knowledgeable. Was very helpful and gave a sense of hope that i don’t think can be found in the traditional health care system.

Owner's reply
Thank you so much Tyler. Peter is quite amazing, so smart. We are proud to have him on our team and so happy he could give you insights that go deeper than traditional healthcare.
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Erin R
August 21, 2026
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Labs can be taken at home and have clear written instructions (can also find video instructions on their website). I met with Peter to discuss my results and he was extremely helpful and kind! I would purchase again!

Owner's reply
Thank you Erin for your kind review! We are so lucky to have Peter. He has helped so many people understand their lab results.
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Evan K
August 7, 2026
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Top notch.

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Thanks Evan! Our team works hard and definitely deserves the praise. If there’s anything that we can improve always let us know. [email protected]
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F N
July 3, 2026
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Best labs, prices, and professional service make this your top choice to only use this company. No other company can compare to the service. Extremely professional and courteous. Thank you, Rachel, for always helping me.

Owner's reply
Glad we could help! We are very passionate about our work here so our tip-top service will never change!
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Omar A
June 15, 2026
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Thanks and well done

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Thanks Omar for your kind words! Our team is the best!
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Susan R
June 3, 2026
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Excellent way to test, quick, easy and discreet.

Owner's reply
Thanks for taking the time to leave a review! So glad we could help. We go over all of our reviews at each meeting!
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Erin K
April 8, 2026
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True Health’s customer service is top notch! I made a mistake when I ordered my Dutch test. I called customer service after hours, but I was able to leave a message. Rachel called me back the next morning, and we were able to get my order fixed! She was kind, helpful, and made the process smooth!

Owner's reply
Thanks for taking the time to compliment our team. They are mighty! So glad we could help you with your health journey.
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Marianne V
March 19, 2026
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I cannot say enough great things about True Health Labs and my experience with the Marcons test. Dr. Peter Stephenson was an absolute wealth of information—extremely intelligent and insightful. He connected all the dots and made me feel like I finally have been heard and seen. After years of dealing with anxiety, OCD, weight gain, inflammation, and depression, it was incredibly comforting to talk to someone who truly understood my situation. Dr. Stephenson spoke straight to my soul and made me feel validated. Thank you, True Health Labs, for providing such an invaluable service and support. Marianne

Owner's reply
Thank you for taking that time to write that review. We’re so lucky to have Peter on the team. His insights, as you pointed out, is incredibly valuable. I’m so glad he was able to help guide you Marianne.
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Jayme T
March 3, 2026
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Ordering tests through True Health Labs was easy and painless. Peter is incredibly knowledgeable and kind. He spent more time explaining and speaking with me than any of my doctors have in the last 3.5 years. Thank you Peter, you are a blessing. And thank you THL for making it possible for the public to avoid the BS control from the medical and insurance industries.

Owner's reply
Wow! Thank you so much for that incredible review. Peter and our clinical team have a great focus on giving insights that would normally never be given. Thank you Jayme for taking the time for the review.
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