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Lp-PLA2 Activity Test


  • The Lp PLA2 Activity lab test measures an inflammation-related enzyme in blood to help estimate heart disease risk.
  • Draw Locations
  • Turnaround Time: 2-4 Business Days on Average. Time may vary.
  • Availability: Allowed if address and testing are outside NY, NJ, MA, RI
  • HSA and FSA Approved

$99.00 USD $105.00

✅ 100% interest free financing + no late fees
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Ordering the Lp-PLA2 Activity Test

Ordering the Lp-PLA2 Activity Test (PLAC) can help assess the risk of cardiovascular conditions by measuring the activity of the Lp-PLA2 enzyme. Interestingly, this enzyme is linked to inflammation in the arteries, which can be a precursor to heart disease.

When you order this test, you can expect the following benefits:

  • Helps evaluate the risk of heart disease by measuring enzyme activity.
  • Provides insights into arterial inflammation levels.
  • Assists in monitoring the effectiveness of lifestyle changes or treatments.
  • Offers a clearer picture of cardiovascular health.
  • Supports informed decision-making with your healthcare provider.

Who Should Consider the PLAC Test

People with a family history of heart disease might find this test beneficial. For example, someone with a parent who had a heart attack at a young age may want to understand their own risk factors better.

Consider ordering this test if you:

  • Have a family history of cardiovascular issues.
  • Are experiencing unexplained fatigue or shortness of breath.
  • Have been diagnosed with high cholesterol or hypertension.
  • Are undergoing treatment for heart disease and need to monitor progress.
  • Have a history of inflammatory conditions, which can affect heart health.

Ordering this test can provide specific insights into your cardiovascular risk by measuring enzyme activity linked to arterial inflammation. Delaying this test might mean missing early signs of potential heart issues, which could be addressed with timely interventions.

High Lp-PLA2 can present a serious situation, so bring your test results to your treating physician.

lp-pla2 activity blood test chart showing inflammation in the arteries

How to Prepare for the Test

Fasting for 10-12 hours is preferred but not required for the Lp-PLA2 Test. It’s important to follow any instructions from your doctor or healthcare professional to ensure the test results are as informative as possible.

Labs Included When Ordering Your Lp-PLA2 Activity Test

Test Name Reference Range Significance Low and High Levels of Lp-PLA2 Activity
Lp-PLA2 Activity <123 Lp-PLA2 is an enzyme linked to inflammation in the arteries. High levels can indicate increased cardiovascular risk. High levels mean increased risk of heart disease due to arterial inflammation.

Low levels mean lower risk of cardiovascular issues.

Reference ranges may differ. Visit the Quest Diagnostics lab test directory for the latest values.


Lp-PLA2 Activity FAQ

Is there Lp-PLA2 Activity testing near me?

To find nearby locations for Lp-PLA2 Activity testing, use the patient service center locator, which includes mobile phlebotomy options. This is especially useful for those monitoring cardiovascular health who need convenient access to testing.

What is the cost of the test?

The cost of the test includes all fees, such as sample collection at patient service center locations. It’s worth ordering to assess cardiovascular risk factors, which can guide preventive measures.

How often should I retest?

Retesting every 6-12 months is recommended to monitor changes in enzyme activity, which can help track the effectiveness of any interventions or lifestyle changes.

How accurate is the test?

The Lp-PLA2 Activity Test uses enzyme-linked immunosorbent assay (ELISA) for precise measurement. TrueHealthLabs.com partners with CLIA-certified laboratories to uphold rigorous testing standards for dependable results.


Medical Review Board

Reviewed by Jeff Donohue M.D. from Body Logic and Brady Hurst DC, CCCN. Written by True Health Lab’s team of editorial health contributors.

Disclaimer: This information is for educational purposes only and not intended as medical advice. Consult your healthcare provider for personalized guidance.


Why Customers Trust True Health Labs – What People are saying

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August 24, 2026
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Peter is very knowledgeable. Was very helpful and gave a sense of hope that i don’t think can be found in the traditional health care system.

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Thank you so much Tyler. Peter is quite amazing, so smart. We are proud to have him on our team and so happy he could give you insights that go deeper than traditional healthcare.
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August 21, 2026
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Labs can be taken at home and have clear written instructions (can also find video instructions on their website). I met with Peter to discuss my results and he was extremely helpful and kind! I would purchase again!

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Thank you Erin for your kind review! We are so lucky to have Peter. He has helped so many people understand their lab results.
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August 7, 2026
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Top notch.

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July 3, 2026
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Best labs, prices, and professional service make this your top choice to only use this company. No other company can compare to the service. Extremely professional and courteous. Thank you, Rachel, for always helping me.

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Glad we could help! We are very passionate about our work here so our tip-top service will never change!
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June 15, 2026
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Susan R
June 3, 2026
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Excellent way to test, quick, easy and discreet.

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Erin K
April 8, 2026
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True Health’s customer service is top notch! I made a mistake when I ordered my Dutch test. I called customer service after hours, but I was able to leave a message. Rachel called me back the next morning, and we were able to get my order fixed! She was kind, helpful, and made the process smooth!

Owner's reply
Thanks for taking the time to compliment our team. They are mighty! So glad we could help you with your health journey.
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Marianne V
March 19, 2026
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I cannot say enough great things about True Health Labs and my experience with the Marcons test. Dr. Peter Stephenson was an absolute wealth of information—extremely intelligent and insightful. He connected all the dots and made me feel like I finally have been heard and seen. After years of dealing with anxiety, OCD, weight gain, inflammation, and depression, it was incredibly comforting to talk to someone who truly understood my situation. Dr. Stephenson spoke straight to my soul and made me feel validated. Thank you, True Health Labs, for providing such an invaluable service and support. Marianne

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Thank you for taking that time to write that review. We’re so lucky to have Peter on the team. His insights, as you pointed out, is incredibly valuable. I’m so glad he was able to help guide you Marianne.
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Jayme T
March 3, 2026
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Ordering tests through True Health Labs was easy and painless. Peter is incredibly knowledgeable and kind. He spent more time explaining and speaking with me than any of my doctors have in the last 3.5 years. Thank you Peter, you are a blessing. And thank you THL for making it possible for the public to avoid the BS control from the medical and insurance industries.

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Wow! Thank you so much for that incredible review. Peter and our clinical team have a great focus on giving insights that would normally never be given. Thank you Jayme for taking the time for the review.
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John B
February 17, 2026
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Rachael answered all my questions about product delivery. I now know exactly how to turn the sample around to the Lab. Thank you

Owner's reply
Thanks John! Our customer support is our shining star. Rachael, Jade, and the entire team is really something special! Thank you so much for taking that time to leave a review.
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