Ordering the Hormone Zoomer Test by Vibrant America
The Salivary Hormone Zoomer test by Vibrant America helps measure hormone levels that can affect energy, mood, sleep, memory, and body weight. This test checks for imbalances in estrogen, progesterone, testosterone, DHEA-S, and cortisol, which can be linked to symptoms like fatigue, hair loss, hot flashes, and trouble concentrating. Interestingly, saliva testing can show hormone patterns throughout the day, which blood tests may not always reveal.
Ordering this test can help you:
- Track hormone changes that may be linked to mood swings or memory problems
- Identify patterns in cortisol that relate to stress or sleep issues
- Check for hormone shifts that may affect weight, muscle, or water retention
- Monitor hormone levels that can impact fertility or menstrual cycles
- Spot early signs of hormone imbalance before symptoms get worse
Who Should Consider Hormone Testing
People who notice changes like feeling tired all day, having trouble sleeping, or experiencing sudden mood changes may benefit from this test. For example, someone who has been feeling more anxious, has noticed hair thinning, and is struggling to focus at work might find answers by checking their hormone levels.
Ordering this test may also be helpful if you:
- Have irregular periods or strong PMS symptoms
- Experience hot flashes or night sweats
- Notice a drop in sex drive or changes in weight without changing your diet
- Feel more forgetful or have trouble concentrating
- Have unexplained headaches that seem to follow a monthly pattern
Testing can help you find out if hormone changes are causing symptoms like fatigue, mood swings, or sleep problems. Delaying this test could mean missing the chance to spot hormone shifts early, which may make it harder to manage symptoms later.
Preparing for Saliva Hormone Panel Collection
Fasting is not required for this test, but it is best to avoid eating, drinking, or brushing your teeth for at least 30 minutes before collecting your saliva sample. Always go by any instructions your doctor or healthcare provider gives you to make sure your sample is collected the right way and your results are as helpful as possible.
Labs Included When Ordering
| Test Name |
Why It Matters |
High / Low Meaning |
| Adrenal Foundation |
Mineralocorticoid Precursors
Deoxycorticosterone
Corticosterone |
These markers show how your adrenal glands are building hormones that help control stress response, salt balance, and blood pressure. They help reveal whether your hormone pathway is flowing smoothly or getting backed up early in the process. |
High: Can suggest the adrenal pathway is being pushed too hard or diverted in a way that may affect fluid balance and stress hormones.
Low: Can suggest weaker adrenal output or reduced upstream hormone production. |
Adrenal Reserve
DHEA
DHEA-S |
DHEA markers help show your body’s reserve-building side of adrenal function, including support for energy, resilience, and sex hormone production. They are often used to understand whether the body is leaning toward recovery and repair or toward burnout. |
High: May reflect stronger androgen drive or overstimulation of adrenal hormone production.
Low: Often fits depleted stress resilience, lower vitality, or reduced hormone-building capacity. |
Total Glucocorticoid Output
Total Cortisol
Total Cortisone |
These markers estimate your overall stress hormone production and how much of it is stored in active versus inactive form. They give a broad picture of whether the body is making too much, too little, or converting cortisol inefficiently. |
High: Can point to a body under prolonged stress load or poor hormone shutoff.
Low: Can fit low adrenal output, fatigue patterns, or difficulty meeting daily demand. |
Cortisol Metabolism Pattern
β-Tetrahydrocortisol (β-THF)
α-Tetrahydrocortisol (α-THF)
β-Tetrahydrocortisone (β-THE)
Cortisol/Cortisone
Metabolized Cortisol (THF+THE) |
These markers show how your body breaks down and recycles cortisol after it is made. They help uncover whether stress hormones are being cleared too fast, lingering too long, or being shifted toward active or inactive forms. |
High: May suggest faster cortisol turnover, higher stress exposure, or increased conversion into active forms.
Low: May suggest slower metabolism or reduced overall cortisol production. |
Daily Free Cortisol/Cortisone Rhythm
Free Cortisol/Cortisone (1st Morning)
Free Cortisol/Cortisone (2nd Morning)
Free Cortisol/Cortisone (Evening)
Free Cortisol/Cortisone (Night)
Free Cortisol/Cortisone (Pooled) |
These readings map your stress hormone rhythm across the day instead of giving only one snapshot. They help show whether you wake up with enough drive, stay steady through the day, and wind down properly at night. |
High: Elevated evening or nighttime levels can fit feeling wired, anxious, or unable to switch off.
Low: Weak morning levels can fit low motivation, fatigue, or trouble getting going. |
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| Sleep and Circadian Rhythm |
Melatonin Rhythm
Melatonin (1st Morning)
Melatonin (2nd Morning)
Melatonin (Evening)
Melatonin (Night)
Melatonin (Pooled) |
Melatonin helps show whether your brain is sending the right sleep signals at the right time. Looking at it through the day can reveal if your body clock is aligned or shifted. |
High: Higher daytime levels or a mistimed rise can suggest a shifted sleep-wake rhythm.
Low: Low nighttime output can fit trouble falling asleep, light sleep, or poor recovery. |
| Sex Hormone Balance |
Estrogen Metabolism Ratios
2-OH E1/4-OH E1
E3/(E1+E2)
2-OH (E1 + E2)/16α-OH E1
2-MeO E1/2-OH E1
4-MeO E1/4-OH E1
4-MeO E2/4-OH E2 |
These ratios show how the body is processing estrogen down safer or less favorable pathways. They are useful for seeing whether estrogen is being cleared and methylated efficiently or lingering in forms that may be more irritating to tissues. |
High: A stronger preference for protective pathways is usually favorable, while buildup of less favorable pathways can raise concern about poor estrogen handling. Better ratios can lower risks of certain types of cancers.
Low: Lower protective ratios can suggest sluggish detox or heavier reliance on less desirable estrogen pathways. |
Progesterone and Calming Metabolites
β-Pregnanediol/E2
β-Pregnanediol
α-Pregnanediol
Allopregnanolone
3α-Dihydroprogesterone
20α-Dihydroprogesterone |
These markers help show progesterone status and how much of it is being turned into calming, brain-active compounds. They can help explain mood changes, sleep issues, cycle changes, and whether estrogen and progesterone feel balanced. |
High: Higher progesterone-to-estrogen balance is often more stabilizing unless symptoms suggest excess sedation.
Low: Lower levels can fit irritability, poor sleep, cycle imbalance, or estrogen feeling less opposed. |
Androgen Pattern
T/Epi-T
Androstenedione
Androsterone
Etiocholanolone
Testosterone (T)
Epi-Testosterone (Epi-T)
5α-DHT
5α,3α-Androstanediol
5β-Androstanediol |
These markers show how your body makes, uses, and breaks down androgen hormones linked to strength, drive, libido, skin, and hair changes. They also help reveal whether testosterone is being pushed more strongly into potent pathways like DHT. |
High: Can fit acne, hair loss, irritability, increased body hair, or a stronger androgen push.
Low: Can fit low drive, reduced muscle support, lower libido, or weaker overall hormone vitality. |
Estrogen Panel
Estradiol (E2)
Estrone (E1)
Estriol (E3)
2-OH Estradiol
2-OH Estrone
4-OH Estradiol
4-OH Estrone
16α-OH Estrone
2-MeO Estradiol
2-MeO Estrone
4-MeO Estradiol
4-MeO Estrone
Total Estrogen |
This group looks at your main estrogens plus the forms they become as the body processes them. It helps connect symptoms like breast tenderness, heavy cycles, hot flashes, sleep changes, and hormone detox capacity. |
High: Can fit stronger estrogen effects, fluid retention, breast tenderness, or slower clearance of estrogen byproducts.
Low: Can fit hot flashes, vaginal dryness, lower resilience, or less hormone support for brain and bone tissues. |
| Cell Stress, Bone Turnover, and Exposure Load |
Oxidative Stress and Bone Turnover
8-Hydroxy-2-deoxyguanosine (8-OHdG)
Deoxypyridinoline (DPD) Crosslinks
Pyridinoline (PYD) Crosslinks |
These markers show whether the body is under wear-and-tear stress and how actively bone tissue is breaking down and rebuilding. They can be useful when looking at aging, inflammation, recovery, and bone health trends. |
High: Can point to more oxidative damage or faster bone breakdown than desired.
Low: Often suggests lower damage burden or slower bone turnover, depending on the marker. |
Environmental Chemical Exposure
Bisphenol A (BPA)
Atrazine
Glyphosate
Monoethyl Phthalate
Mono-2-ethylhexyl Phthalate
Mono-(2-ethyl-5-hydroxyhexyl) Phthalate
Mono-(2-ethyl-5-oxohexyl) Phthalate
Methylparaben
Ethylparaben
Butylparaben
Propylparaben
Triclosan
Perchlorate |
These markers look for common chemical exposures from plastics, personal care products, food packaging, herbicides, and water contaminants. They help show how much outside chemical burden may be adding pressure to hormone balance, thyroid function, and detox pathways. |
High: Suggests greater recent exposure and more possible pressure on hormone and detox systems.
Low: Usually reflects lower recent exposure, which is generally favorable. |
| Salivary Stress Response |
Saliva Cortisol/Cortisone Curve
Saliva Cortisol/Cortisone – Waking
Saliva Cortisol/Cortisone – W +30 min.
Saliva Cortisol/Cortisone – W +60 min.
Saliva Cortisol/Cortisone – Evening
Saliva Cortisol/Cortisone – Night
Saliva Cortisol/Cortisone – Total
Saliva Cortisol/Cortisone – Insomnia (optional) |
This saliva series tracks your cortisol rise after waking and how it changes through the day. It is especially helpful for spotting a flat morning response, an overactive stress pattern, or nighttime hormone activity that may disturb sleep. |
High: A strong late-day or nighttime rise can fit hyperarousal, stress overload, or insomnia patterns.
Low: A weak waking rise can fit burnout-style fatigue, poor alertness, or low daytime stamina. |
FAQ
Can I get the Hormone Zoomer near me?
This is a home test kit, so you can collect your saliva sample wherever you are, and use the draw location link at the top of the page if you need help. For people dealing with symptoms like fatigue or mood swings, being able to collect your sample at home makes it easier to get tested without extra travel or waiting.
How do I interpret the test results?
While your doctor should help you understand your results, you can also use our one-on-one test results review service with our clinical team for a detailed explanation.
What is the cost of the test?
The price you see includes shipping both to you and back to the lab, but some locations may charge a draw fee. Ordering this test can help you find out if hormone changes are causing symptoms like tiredness or trouble sleeping, so you can start feeling better sooner.
How often should I retest?
It is usually best to retest every 3 to 6 months, especially if you are making changes to your diet, supplements, or hormone therapy. Regular testing helps you track progress and adjust your plan if hormone levels are still not where they should be.
How accurate is the test?
This test uses liquid chromatography-tandem mass spectrometry (LC-MS/MS) for hormone measurement, which is highly specific and sensitive for saliva samples. The test has a specificity of 98% and a sensitivity of 97%. TrueHealthLabs.com works with CLIA-certified and CAP-certified labs to maintain high-quality testing standards you can trust.
Important Note
- We do not advise discontinuing any necessary medications or supplements. We recommend you consult your primary doctor before changing your medication or supplement intake.
Medical Review Board
Reviewed by Jeff Donohue M.D. from Body Logic and Brady Hurst DC, CCCN. Written by True Health Lab’s team of editorial health contributors.
Disclaimer: This information is for educational purposes only and not intended as medical advice. Consult your healthcare provider for personalized guidance.
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