Ordering the DNA Oxidative Damage Assay
The DNA Oxidative Damage Assay measures 8-hydroxy-2-deoxyguanosine (8-OHdG) in urine, which helps detect oxidative stress and DNA damage in the body. This test is often used by people who want to track how their body is handling free radicals, which can affect cell health and may be linked to certain chronic conditions. Interestingly, 8-OHdG is one of the most studied markers for DNA damage and is used in research to monitor environmental and lifestyle impacts on genetic material.
Ordering the DNA Oxidative Damage Assay provides several specific benefits:
- Tracks the body’s response to oxidative stress and free radical exposure.
- Helps monitor the effectiveness of antioxidant therapies or lifestyle changes.
- Assists in identifying early signs of DNA damage before symptoms appear.
- Supports evaluation of risk for certain chronic conditions related to oxidative stress.
- Offers a non-invasive way to assess cellular health using a simple urine sample.
Who Might Benefit from Oxidative Stress Marker Testing
People who are exposed to high levels of environmental toxins, such as those living in urban areas with air pollution, may want to check for DNA damage. For example, someone who has recently started a new job in an industrial setting may want to know if their body is being affected by increased exposure to chemicals.
Ordering this test may also be helpful in these situations:
- People with a family history of chronic conditions linked to oxidative stress.
- Those who have recently undergone radiation or chemotherapy treatments.
- People following a new antioxidant-rich diet or supplement plan.
- Individuals experiencing unexplained fatigue or low energy levels.
- People who have recently traveled to areas with high environmental pollution, as this can increase oxidative stress markers.
Testing for oxidative DNA damage can help detect changes in the body’s response to free radicals, allowing for early adjustments in diet, supplements, or lifestyle. Delaying this test may mean missing the chance to catch rising oxidative stress before it leads to more significant cellular changes. To get started, order the test and take the first step toward tracking your body’s response to oxidative stress.
Preparing for Urinary 8-OHdG and Related Biomarker Testing
Fasting is not required for this urine-based test, so you can collect your sample at any time of day. Always follow any instructions your doctor or healthcare provider gives you to make sure your sample is collected and handled correctly.
Labs Included When Ordering Your DNA Oxidative Damage Assay
| Test Name | Reference Range | What This Marker Means | Low and High Levels of DNA Oxidative Damage Assay |
|---|---|---|---|
| 8-hydroxy-2-deoxyguanosine (8-OHdG) | <18.9 | 8-OHdG is a marker found in urine that shows how much oxidative damage has happened to DNA. High levels can indicate increased free radical activity and potential cell damage. | High levels mean your body is experiencing more oxidative stress, which can increase the risk for certain chronic conditions.
Low levels mean there is less oxidative damage to DNA, which is generally a positive sign. |
Reference ranges may change slightly as labs update their methods and guidelines.
DNA Oxidative Damage Assay FAQ
Is there DNA Oxidative Damage Assay testing near me?
This is a test kit you can use at home, so you can collect your urine sample locally and send it to the lab. Since oxidative stress can be affected by daily exposures, having a convenient way to collect your sample helps you get results without delay.
How do I interpret the test results?
While your treating physician should help you interpret your results, we also offer a one-on-one test results review with our clinical team to help you understand your results and next steps.
What is the cost of the test?
The price you see for the DNA Oxidative Damage Assay includes standard shipping to you and return shipping to the lab, but draw fees may apply. Ordering this test can help you spot early signs of oxidative stress, which may help you address issues sooner and recover more quickly.
How often should I retest?
It’s recommended to retest every 3 to 6 months, especially if you are making changes to your diet, supplements, or environment. Regular testing helps you track changes in oxidative stress and see if your efforts are making a difference.
How accurate is the test?
This test uses high-performance liquid chromatography with electrochemical detection, which is highly specific for 8-OHdG. The specificity is 98% and sensitivity is 97%. TrueHealthLabs.com partners with CLIA-certified and CAP-certified laboratories to uphold rigorous testing standards for dependable results.
Medical Review Board
Reviewed by Jeff Donohue M.D. from Body Logic and Brady Hurst DC, CCCN. Written by True Health Lab’s team of editorial health contributors.
Disclaimer: This information is for educational purposes only and not intended as medical advice. Consult your healthcare provider for personalized guidance.
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