Systemic Autoimmune Reactivity Screen | Cyrex Labs Array #5
Many studies show that the autoimmune antibody can be elevated in the blood many years before symptoms occur. Cyrex Labs have now developed their Cyrex Labs Array #5, a comprehensive autoimmune screen that helps in the early detection of autoimmunity. If detected early, natural and/or medical interventions can begin in order to minimize long-term illness and promote a better quality of life. Multiple autoimmune antibodies are tested in this panel due to the fact that more than 40% of those with auto-antibodies to one area have auto-antibodies to other areas of the body. Cyrex Array #5 tests the gamut of autoimmune antibodies in order to minimize “missing” a potential autoimmune condition. What’s Being Tested:
| ANTIGEN | ANTIBODIES ASSOCIATED WITH*: *This test by itself is not diagnostic for any condition or disease | BODY TISSUE: |
| Parietal Cell + ATPase IgG + IgA Combined | Gastric Autoimmunity Chronic Atrophic Gastritis Pernicious Anemia | Gastrointestinal |
| Intrinsic Factor IgG + IgA Combined | Autoimmune Gastritis Pernicious Anemia | |
| ASCA + ANCA IgG + IgA Combined | Beh̤ets Syndrome with GI Involvement Crohns Disease Long-term use of Anti-Thyroid Medication Ulcerative Colitis Vasculitis | |
| Tropomyosin IgG + IgA Combined | Autoimmune Cardiovascular Diseases Colon Autoimmunity Ulcerative Colitis | |
| Thyroglobulin IgG + IgA Combined | Autoimmune Thyroid Disease Hashimotos Thyroiditis Graves Disease | Thyroid |
| Thyroid Peroxidase(TPO) IgG + IgA Combined | Autoimmune Thyroid Disease Graves Disease Hashimoto’s Thyroiditis Vitiligo | |
| 21 Hydroxylase (Adrenal Cortex) IgG + IgA Combined | Addison’s Disease Adrenal Autoimmunity Adrenal Insufficiency Atrophic Gastritis Autoimmune Endocrine Disorders Diabetes Insipidus Graves’ Disease Hashimoto’s Thyroiditis Vitiligo | Adrenal |
| Myocardial Peptide IgG + IgA Combined | Acute Rheumatic Fever Autoimmune Myocarditis Heart Disease Heart Trauma Rheumatic Heart Disease | Cardiovascular |
| Alpha-Myosin IgG + IgA Combined | Autoimmune Myocarditis Dilated Cardiomyopathy Myasthenia Gravis Rheumatic Heart Disease | |
| Phospholipid IgG + IgA Combined | Antiphospholipid Syndrome Non-Insulin-Dependent Diabetes Mellitus (NIDDM) Systemic Lupus Erythematosus (SLE) | Cardiovascular and Endocrine |
| Platelet Glycoprotein IgG + IgA Combined | Arterial Thrombosis Autoimmune Thrombocytopenia Cardiovascular Disease Coronary Artery Disease Systemic Lupus Erythematosus (SLE) | |
| Ovary/Testis IgG + IgA Combined* Ovary and Testis are tested together to avoid any confusion arising out of potential cross-reactivity. | Autoimmune Endocrine Disorders Autoimmune Polyendocrine Syndrome Type 1 Hypogonadism Premature Menopause Premature Ovarian Failure | Reproductive |
| Fibulin IgG + IgA Combined | Atherosclerotic Lesions Osteoarthritis | Joint |
| Collagen Complex IgG + IgA Combined | Arthritis Goodpasture’s Syndrome* Type 1 Bullous SLE *rat study | |
| Arthritic Peptide IgG + IgA Combined | Mixed Connective Tissue Disease Osteoarthritis Rheumatoid Arthritis | |
| Osteocyte IgG + IgA Combined | Osteoclastogeneis Osteopenia Osteoporosis | Bone |
| Cytochrome P450 (Hepatocyte) IgG + IgA Combined | Autoimmune Hepatitis Type 2 Chronic Hepatitis C Heptocellular Carcinoma Liver/Mycrosomal Autoimmunities | Liver and Endocrine |
| Insulin + Islet Cell Antigen IgG + IgA Combined | Insulin Autoimmune Hypoglycaemia Insulinoma Type 1 Diabetes Unexplained Hypoglycaemia | |
| Glutamic Acid Decarboxylase 65 (GAD 65) IgG + IgA Combined | Battan Disease Celiac Disease Cerebellar Ataxia Non-Celiac Gluten Sensitivity Polyendocrine Autoimmune Syndrome Stiff-Person Syndrome Type 1 Diabetes | |
| Myelin Basic Protein IgG + IgA Combined | Multiple Sclerosis Autism PANDAS / ANDAS / OCD Systemic Lupus Erythematosus (SLE) Toxin Exposure | Neuronal |
| Asialoganglioside IgG + IgA Combined | Chronic Inflammatory Demyelinating Polyneuropathy Cerebrovascular Accidents Cranial Trauma Guillain Barr̩ Syndrome Miller Fisher Syndrome Motor Neuron Disease Multifocal Motor Neuropathy Multiple Sclerosis Myasthenia Gravis PANDAS / ANDAS / OCD Rheumatoid Arthritis Sensorimotor Neuropathy Systemic Lupus Erythematosus (SLE) | |
| Alpha + Beta Tubulin IgG + IgA Combined | Alcoholic Liver Disease Demyelinating Disease Graves Disease Hashimotos Thyroiditis Infectious agent exposure PANDAS / ANDAS / OCD Rheumatoid Arthritis Recent Onset Type 1 Diabetes Toxin Exposure | |
| Cerebellar IgG + IgA Combined | Autism Celiac Disease Gluten Ataxia Paraneoplastic Cerebellar Degeneration Syndrome Opsoclonus-Myoclonus Syndrome | |
| Synapsin IgG + IgA Combined | Demyelinating Diseases Inhibited Neurotransmitter Release Systemic Lupus Erythematosus (SLE) Multiple Sclerosis |
Fasting: No (review kit instructions) Specimen: Blood, Cyrex Test Kit (Draw Location | How It Works | FAQs) Turnaround Time: 14 Business days (once the lab receives your sample) IMPORTANT NOTE:
- It is recommended to be clear of immunosuppressants and/or corticosteroids for at least 60 days prior to taking this test. Please consult with your prescribing healthcare provider.
- NOT AVAILABLE IN NEW YORK. SPECIMEN DRAWS CAN BE COMPLETED IN NEIGHBORING STATES.
- We are now accepting international orders. Sample must be received within 7 days. Additional return shipping fees may apply.
- READ: IMPORTANT Cyrex FAQs
- Due to circumstances beyond our control, pediatric blood draws are not included under Cyrex’s contracted phlebotomy. All patients 15 years of age and younger are included in the pediatric group. Pediatric blood draws must be scheduled by the parents at a laboratory of their choosing, and must be paid for by the parent at the time of service.
