What The BiomeBurden Complete Test Is
The BiomeBurden Complete test checks your immune response to yeast, molds, and gut microbes all at once. It looks at both IgG and IgA antibodies to show short-term and long-term reactions, giving a fuller picture of how your body is dealing with hidden microbial stress. This panel includes less commonly tested markers like Actin Peptide, Candidalysin, and Ubiquitin, which can reveal subtle immune activation missed on standard stool or culture tests.
By measuring responses to Candida species, Saccharomyces strains, food-derived molds, and enteropathogens, it shows how your gut and immune system may be working overtime. Together, these markers help uncover patterns linked to fatigue, digestive changes, skin issues, brain fog, and recurring infections.
Why The BiomeBurden By Cyrex Labs Is Important
This test matters because it helps find immune triggers that standard gut tests rarely detect. Some markers, like Alpha-Enolase, reflect when your body is reacting to cell stress, while others—like Neutrophil Activation Factors—show when your immune defenses may be stuck in “high alert.” The IgG and IgA patterns help distinguish old exposures from active irritation so you can better understand what’s driving symptoms.
Measuring multiple Candida types side-by-side is valuable because different strains can activate the immune system in different ways. Testing Th1, Th2, Th17, and T-Reg balance helps reveal how your immune system is responding and whether it may be leaning toward inflammation or poor microbial tolerance. This makes the BiomeBurden Complete panel helpful for people dealing with chronic symptoms without clear answers.
Why You Should Consider Ordering This Gut Related Test
Consider ordering this test if you’ve been struggling with ongoing issues that feel “mystery-like,” especially when routine labs come back normal. The wide range of markers helps you see whether yeast, molds, or gut bugs may be draining your energy or overwhelming your immune system. Results may guide more targeted diet, environment, or treatment decisions, helping you avoid guesswork.
If you’ve had recurring digestive discomfort, stubborn sinus or skin problems, or symptoms that flare after eating fermented foods or high-sugar meals, this test can give clarity. It also helps people working with functional or integrative clinicians who want a deeper look at immune signaling patterns.
- Shows immune reactions to Candida species, molds, and gut microbes that routine tests often miss.
- Helps identify whether symptoms may be tied to microbial overload or hidden immune activation.
- Provides insights into Th1, Th2, Th17, and T-Reg balance for a clearer view of immune patterns.
- Useful for chronic digestive, skin, sinus, mood, or fatigue-related symptoms.
Labs Included When Ordering Your BiomeBurden Complete Test
| Biomarker | What This Biomarker Means | High & Low Values |
|---|---|---|
| Candida Albicans IgG + IgA | Shows your immune response to a common yeast that can irritate the gut, skin, and sinuses. IgA reflects more recent exposure while IgG points to longer-term reactions. | High: May suggest ongoing irritation or repeated exposure. |
| Food-Derived Molds IgG + IgA | Shows whether your immune system reacts to molds commonly found in foods, which may contribute to digestive or sinus discomfort. | High: May indicate sensitivity or heightened immune activation from mold-containing foods. |
| Th1 / Th2 Ratio | Shows whether your immune system leans toward inflammation (Th1) or allergic-type responses (Th2), helping reveal immune balance issues. | High: May indicate a stronger Th1 pattern linked to irritation or immune overdrive.
Low: May indicate a stronger Th2 pattern linked to sensitivities or poor microbial tolerance. |
| Ubiquitin IgG + IgA | Ubiquitin reflects immune recognition of cell-stress proteins, which may appear when tissues are irritated or under chronic immune pressure. | High: May suggest increased cell stress or immune activation. |
| Saccharomyces Cerevisiae Glucan IgG + IgA | Measures immune responses to yeast components often found in fermented foods and probiotics. Helpful for people who react poorly to these foods. | High: May indicate sensitivity or ongoing irritation from Saccharomyces exposure. |
Show More Biomarkers
| Biomarker | What This Biomarker Means | High & Low Values |
|---|---|---|
| Saccharomyces Boulardii IgG + IgA | Shows response to a probiotic yeast sometimes linked with bloating or discomfort in sensitive individuals. | High: May indicate irritation or sensitivity to this yeast. |
| Candida Tropicalis + C. Glabrata IgG + IgA | Detects immune responses to less common Candida species that may affect gut or sinus health. | High: May suggest immune activation from these strains. |
| Candida Parapsilosis + Krusei IgG + IgA | Assesses reactions to harder-to-detect Candida forms often missed on standard testing. | High: May reflect irritation or exposure. |
| Candida Auris IgG + IgA | Screens for immune signals tied to a resistant yeast increasingly seen in healthcare settings. | High: May indicate immune recognition of this strain. |
| Candidalysin IgG + IgA | Shows response to a toxin released by Candida that can irritate the gut lining. | High: May signal gut barrier irritation. |
| Candida Germ Tube Protein IgG + IgA | Indicates recognition of an early-form Candida structure tied to overgrowth. | High: May signal immune response to active Candida forms. |
| Alpha-Enolase IgG + IgA | Reflects immune response to a cell enzyme associated with tissue stress or irritation. | High: May indicate immune activation. |
| Aerobic Enteropathogens IgG + IgA | Shows reactions to oxygen-loving gut microbes that may cause digestive changes. | High: May reflect recent or ongoing microbial irritation. |
| Anaerobic Enteropathogens IgG + IgA | Detects immune signals toward microbes that thrive without oxygen, often involved in gut imbalance. | High: May suggest irritation or overgrowth. |
| Neutrophil Activation Factors IgG + IgA | Shows if immune defense cells are being triggered repeatedly, pointing to hidden stressors. | High: May indicate frequent immune activation. |
| Actin Peptide IgG + IgA | Reflects immune recognition of structural cell proteins, sometimes linked to irritation of gut tissues. | High: May reflect irritation or barrier stress. |
| WBC, Total Lymphocytes, Total T Cells, Th17, T-Reg, Th17/T-Reg Ratio | Shows how your immune system is balancing inflammation and regulation, helping identify patterns tied to chronic symptoms. | High: May indicate increased immune activity.
Low: May reflect reduced immune signaling or depletion. |
References can change over time. Check lab for most recent ranges.
According to this PubMed source, research shows that Candida-related immune responses can influence both gut function and systemic inflammation, highlighting the importance of accurate immune-based testing.
BiomeBurden FAQ
Is there BiomeBurden Complete testing near me?
Yes. You can use our national draw center locator to find a nearby site, or choose mobile phlebotomy if travel is difficult. This helps you get tested quickly without delaying answers you need.
What is the cost of the test?
The price includes the lab order, processing, and shipping. It’s worth considering if you’ve been searching for a deeper explanation for ongoing symptoms that haven’t improved.
Can you help me interpret my test results?
Your doctor should review your results, but we can help you understand them through our One-On-One Results Review service.
How often should I retest?
Most people retest every 4–6 months to monitor changes in immune reactivity. This helps track whether your plan is working.
How accurate is the test?
Cyrex uses advanced immune assay methods that detect both IgG and IgA with high specificity and sensitivity. All testing is performed in a CLIA-certified laboratory for accuracy you can trust.
Will food, supplements, or antifungals affect my results?
Strong antifungals or recent infections may shift antibody levels. Most people wait 2–4 weeks after major changes before testing.
Do symptoms need to be active to get accurate results?
No. IgG and IgA markers can show both past and current immune activity, even if symptoms come and go.
Can children take this test?
Yes, but parents should confirm with their pediatric provider to ensure the timing and context are appropriate.
Does this panel replace stool testing?
It doesn’t replace stool testing but adds immune-based insights that stool alone cannot detect.
Medical Review Board
Reviewed by Jeff Donohue M.D. from Body Logic and Brady Hurst DC, CCCN. Written by True Health Lab’s team of editorial health contributors.
Disclaimer: This information is for educational purposes only and not intended as medical advice. Consult your healthcare provider for personalized guidance.
Why Customers Trust True Health Labs – What People are saying
Also rated 4.6 out of 5 based on 3452 ShopperApproved reviews- See all TrueHealthLabs.com reviews.
