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MTHFR (Methylenetetrahydrofolate Reductase) DNA Analysis


$199.00 $488.84

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MTHFR (Methylenetetrahydrofolate Reductase Gene), DNA Analysis

MTHFR, abbreviated from “methylenetetrahydrofolate reductase”, is an enzyme that helps your body maintain several important processes, including neurotransmitter production, DNA protection, and detoxification.

Mutated copies of the MTHFR genes can lead to chronic illnesses like autism, autoimmune disorders, depression, anxiety, Alzheimer’s disease, arteriosclerosis, and ADHD.


Mutations of these genes (C677T and A1298C) can greatly disturb the way we process and use several critical nutrients like folic acid, B6, B12, SAM-E, and methionine.


A good sign that the methylation pathway isn’t working well is by testing homocysteine in the blood. Homocysteine is a harmful (especially to the cardiovascular system) amino acid that gets overproduced with MTHFR mutation issues and/or nutritional deficiency. Homocysteine is an add-on to this panel.


Knowing which MTHFR genes are mutated can help determine what form and amount of nutrients that are needed to help restore function to the methylation pathway.

What’s Being Tested:


  • Methylenetetrahydrofolate Reductase Variant (MTHFR)
  • The purpose of this test is to determine if you have one, two, are no copies of either of the two known mutations in the MTHFR gene, C677T and A1298C.
  • Sample Report


Fasting: No

Specimen Type: Blood (Draw Location | How It Works | FAQs)

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comments: Your customer service is excellent - responsive and goes the extra mile. Worked with Rachel, who was terrific. The website lagged a lot, but may be new year's eve traffic. Also, a coupon supposed to expire on 1/1/22 did not work when ordered on 12/31/21. Overall however, your service and availability of labs, which is most important, is excellent.

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